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Items: 1 to 20 of 32

1.
The adhesion GPCRs CELSR1–3 and LPHN3 engage G proteins via distinct activation mechanisms
Duy Lan Huong Bui, Andrew Roach, Jingxian Li, Sumit J. Bandekar, Elizabeth Orput, Ritika Raghavan, Demet Araç, Richard C. Sando
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112552. Published online 2023 May 23. doi: 10.1016/j.celrep.2023.112552
PMCID:
PMC10592476
AbstractArticlePDF–4.9M
2.
ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to the incretin polypeptide GIP
Oscar M. Vidal, Jorge I. Vélez, Mauricio Arcos-Burgos
Sci Rep. 2022; 12: 15922. Published online 2022 Sep 23. doi: 10.1038/s41598-022-20343-z
PMCID:
PMC9508192
AbstractArticlePDF–4.7M
3.
Thwarting of Lphn3 Functions in Cell Motility and Signaling by Cancer-Related GAIN Domain Somatic Mutations
Monserrat Avila-Zozaya, Brenda Rodríguez-Hernández, Feliciano Monterrubio-Ledezma, Bulmaro Cisneros, Antony A. Boucard
Cells. 2022 Jun; 11(12): 1913. Published online 2022 Jun 13. doi: 10.3390/cells11121913
PMCID:
PMC9221416
AbstractArticlePDF–12M
4.
Convergent selective signaling impairment exposes the pathogenicity of latrophilin-3 missense variants linked to inheritable ADHD susceptibility
Ana L. Moreno-Salinas, Brian J. Holleran, Estefania Y. Ojeda-Muñiz, Kerlys G. Correoso-Braña, Sheila Ribalta-Mena, José-Carlos Ovando-Zambrano, Richard Leduc, Antony A. Boucard
Mol Psychiatry. 2022; 27(5): 2425–2438. Published online 2022 Apr 7. doi: 10.1038/s41380-022-01537-3
PMCID:
PMC9135631
AbstractArticlePDF–5.0M
5.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
6.
N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation
Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas
Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.
Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017
PMCID:
PMC8282764
AbstractArticlePDF–3.4M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
Tissue Expression Of LPHN3 in Breast Cancer: An Immunohistochemistry Method
Kwuntida Uthaisar Kotepui, Manas Kotepui, Duangjai Piwkham, Apiram Songsri, Lek Charoenkijkajorn, Tidamas Kongnok, Yupaporn Chanil
Asian Pac J Cancer Prev. 2020 Nov; 21(11): 3339–3343. doi: 10.31557/APJCP.2020.21.11.3339
PMCID:
PMC8033104
AbstractArticlePDF–383K
9.
G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3
Signe Mathiasen, Tiago Palmisano, Nicole A. Perry, Hannah M. Stoveken, Alex Vizurraga, Dyke P. McEwen, Najeah Okashah, Tobias Langenhan, Asuka Inoue, Nevin A. Lambert, Gregory G. Tall, Jonathan A. Javitch
Nat Chem Biol. Author manuscript; available in PMC 2021 Mar 24.
Published in final edited form as: Nat Chem Biol. 2020 Dec; 16(12): 1343–1350. Published online 2020 Aug 10. doi: 10.1038/s41589-020-0617-7
Correction in:
Nat Chem Biol. 2020 Aug 17
PMCID:
PMC7990041
AbstractArticlePDF–2.5M
10.
Brain structural and functional substrates of ADGRL3 (latrophilin 3) haplotype in attention-deficit/hyperactivity disorder
Ana Moreno-Alcázar, Josep A. Ramos-Quiroga, Marta Ribases, Cristina Sánchez-Mora, Gloria Palomar, Rosa Bosch, Josep Salavert, Lydia Fortea, Gemma C. Monté-Rubio, Erick J. Canales-Rodríguez, Michael P. Milham, F. Xavier Castellanos, Miquel Casas, Edith Pomarol-Clotet, Joaquim Radua
Sci Rep. 2021; 11: 2373. Published online 2021 Jan 27. doi: 10.1038/s41598-021-81915-z
PMCID:
PMC7840726
AbstractArticlePDF–1.6M
11.
ADGRL3 (LPHN3) variants predict substance use disorder
Mauricio Arcos-Burgos, Jorge I. Vélez, Ariel F. Martinez, Marta Ribasés, Josep A. Ramos-Quiroga, Cristina Sánchez-Mora, Vanesa Richarte, Carlos Roncero, Bru Cormand, Noelia Fernández-Castillo, Miguel Casas, Francisco Lopera, David A. Pineda, Juan D. Palacio, Johan E. Acosta-López, Martha L. Cervantes-Henriquez, Manuel G. Sánchez-Rojas, Pedro J. Puentes-Rozo, Brooke S. G. Molina, MTA Cooperative Group, Margaret T. Boden, Deeann Wallis, Brett Lidbury, Saul Newman, Simon Easteal, James Swanson, Hardip Patel, Nora Volkow, Maria T. Acosta, Francisco X. Castellanos, Jose de Leon, Claudio A. Mastronardi, Maximilian Muenke
Transl Psychiatry. 2019; 9: 42. Published online 2019 Jan 29. doi: 10.1038/s41398-019-0396-7
PMCID:
PMC6351584
AbstractArticlePDF–2.3M
12.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
Latrophilin receptors: novel bronchodilator targets in asthma
A Faiz, C Donovan, M AE Nieuwenhuis, M van den Berge, D S Postma, S Yao, C Y Park, R Hirsch, J J Fredberg, G Tjin, A J Halayko, K L Rempel, J P T Ward, T Lee, Y Bossé, D C Nickle, M Obeidat, Judith M Vonk, J L Black, B G Oliver, R Krishnan, B McParland, J E Bourke, J K Burgess
Thorax. 2017 Jan; 72(1): 74–82. Published online 2016 Jun 20. doi: 10.1136/thoraxjnl-2015-207236
PMCID:
PMC5329048
AbstractArticlePDF–1.5M
15.
An Ultraconserved Brain-specific Enhancer within ADGRL3 (LPHN3) Underpins ADHD Susceptibility
Ariel F. Martinez, Yu Abe, Sungkook Hong, Kevin Molyneux, David Yarnell, Heiko Löhr, Wolfgang Driever, Maria T. Acosta, Mauricio Arcos-Burgos, Maximilian Muenke
Biol Psychiatry. Author manuscript; available in PMC 2017 Dec 15.
Published in final edited form as: Biol Psychiatry. 2016 Dec 15; 80(12): 943–954. Published online 2016 Jul 14. doi: 10.1016/j.biopsych.2016.06.026
PMCID:
PMC5108697
AbstractArticlePDF–1.5M
16.
Structural Basis of Latrophilin - FLRT - UNC5 Interaction in Cell Adhesion
Yue C. Lu, Olha V. Nazarko, Richard Sando, III, Gabriel S. Salzman, Nan-Sheng Li, Thomas C. Südhof, Demet Araç
Structure. Author manuscript; available in PMC 2016 Apr 29.
Published in final edited form as: Structure. 2015 Sep 1; 23(9): 1678–1691. Published online 2015 Jul 30. doi: 10.1016/j.str.2015.06.024
PMCID:
PMC4851429
AbstractArticlePDF–2.1M
17.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
18.
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein–Coupled Receptors
Jörg Hamann, Gabriela Aust, Demet Araç, Felix B. Engel, Caroline Formstone, Robert Fredriksson, Randy A. Hall, Breanne L. Harty, Christiane Kirchhoff, Barbara Knapp, Arunkumar Krishnan, Ines Liebscher, Hsi-Hsien Lin, David C. Martinelli, Kelly R. Monk, Miriam C. Peeters, Xianhua Piao, Simone Prömel, Torsten Schöneberg, Thue W. Schwartz, Kathleen Singer, Martin Stacey, Yuri A. Ushkaryov, Mario Vallon, Uwe Wolfrum, Mathew W. Wright, Lei Xu, Tobias Langenhan, Helgi B. Schiöth
Pharmacol Rev. 2015 Apr; 67(2): 338–367. Published online 2015 Apr. doi: 10.1124/pr.114.009647
PMCID:
PMC4394687
AbstractArticlePDF–3.0M
19.
Influence of a Latrophilin 3 (LPHN3) risk haplotype on event-related potential measures of cognitive response control in attention-deficit hyperactivity disorder (ADHD)
Andreas J. Fallgatter, Ann-Christine Ehlis, Thomas Dresler, Andreas Reif, Christian P. Jacob, Mauricio Arcos-Burgos, Maximilian Muenke, Klaus-Peter Lesch
Eur Neuropsychopharmacol. Author manuscript; available in PMC 2014 Aug 13.
Published in final edited form as: Eur Neuropsychopharmacol. 2013 Jun; 23(6): 458–468. Published online 2012 Dec 12. doi: 10.1016/j.euroneuro.2012.11.001
PMCID:
PMC4131948
AbstractArticlePDF–182K
20.
The genetics of attention deficit/hyperactivity disorder in adults, a review
B Franke, S V Faraone, P Asherson, J Buitelaar, C H D Bau, J A Ramos-Quiroga, E Mick, E H Grevet, S Johansson, J Haavik, K-P Lesch, B Cormand, A Reif
Mol Psychiatry. 2012 Oct; 17(10): 960–987. Published online 2011 Nov 22. doi: 10.1038/mp.2011.138
PMCID:
PMC3449233
AbstractArticlePDF–962K

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