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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 110708492.

AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation

Xiaoming Dai, Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo, Peiqiang Yan, Fangtao Chi, Tao Zhang, Hiroyuki Inuzuka, John M. Asara, Ping Wang, Jianping Guo, Wenyi Wei

Nat Metab. Author manuscript; available in PMC 2024 May 6.

Published in final edited form as: Nat Metab. 2023 Feb; 5(2): 265–276. Published online 2023 Feb 2. doi: 10.1038/s42255-022-00732-4

PMCID:: PMC11070849

Abstract Article PDF–5.4M

Select item 109059443.

AMPKα2 promotes tumor immune escape by inducing CD8+ T-cell exhaustion and CD4+ Treg cell formation in liver hepatocellular carcinoma

Yan Ouyang, Yan Gu, Xinhai Zhang, Ya Huang, Xianpeng Wei, Fuzhou Tang, Shichao Zhang

BMC Cancer. 2024; 24: 276. Published online 2024 Mar 1. doi: 10.1186/s12885-024-12025-y

PMCID:: PMC10905944

Abstract Article PDF–11M

Select item 109042774.

The BHLHE40‒PPM1F‒AMPK pathway regulates energy metabolism and is associated with the aggressiveness of endometrial cancer

Kazuo Asanoma, Hiroshi Yagi, Ichiro Onoyama, Lin Cui, Emiko Hori, Minoru Kawakami, Shoji Maenohara, Kazuhisa Hachisuga, Hiroshi Tomonobe, Keisuke Kodama, Masafumi Yasunaga, Tatsuhiro Ohgami, Kaoru Okugawa, Hideaki Yahata, Hiroyuki Kitao, Kiyoko Kato

J Biol Chem. 2024 Mar; 300(3): 105695. Published online 2024 Jan 30. doi: 10.1016/j.jbc.2024.105695

PMCID:: PMC10904277

Abstract Article PDF–6.0M

Select item 107941125.

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1

Nazma Malik, Bibiana I. Ferreira, Pablo E. Hollstein, Stephanie D. Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca Gilson, Kristina Hellberg, Lingjing Fang, Arlo Sheridan, Nasun Hah, Gerald S. Shadel, Uri Manor, Reuben J. Shaw

Science. Author manuscript; available in PMC 2024 Jan 18.

Published in final edited form as: Science. 2023 Apr 21; 380(6642): eabj5559. Published online 2023 Apr 21. doi: 10.1126/science.abj5559

PMCID:: PMC10794112

Abstract Article PDF–3.3M

Select item 107542876.

Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers

Fiona A. Ross, Simon A. Hawley, Fiona M. Russell, Nicola Goodman, D. Grahame Hardie

Biochem J. 2023 Dec 13; 480(23): 1951–1968. Published online 2023 Dec 1. doi: 10.1042/BCJ20230380

PMCID:: PMC10754287

Abstract Article PDF–2.2M

Select item 102374227.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100729068.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 98522799.

Impact of AMPK on cervical carcinoma progression and metastasis

Paweł Konieczny, Tomasz Adamus, Maciej Sułkowski, Klaudia Skrzypek, Marcin Majka

Cell Death Dis. 2023 Jan; 14(1): 43. Published online 2023 Jan 19. doi: 10.1038/s41419-023-05583-9

PMCID:: PMC9852279

Abstract Article PDF–3.6M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 929844911.

ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation

Dongsheng Bai, Jiaying Du, Xiumin Bu, Wangjia Cao, Tifan Sun, Jiawei Zhao, Yue Zhao, Na Lu

Autophagy. 2022; 18(7): 1673–1693. Published online 2021 Nov 25. doi: 10.1080/15548627.2021.1997051

PMCID:: PMC9298449

Abstract Article PDF–7.7M

Select item 911781812.

Targeting USP9X–AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma

Feng-Kun Zhang, Qian-Zhi Ni, Kang Wang, Hui-Jun Cao, Dong-Xian Guan, Er-Bin Zhang, Ning Ma, Yi-Kang Wang, Qian-Wen Zheng, Sheng Xu, Bing Zhu, Tian-Wei Chen, Ji Xia, Xiao-Song Qiu, Xu-Fen Ding, Hao Jiang, Lin Qiu, Xiang Wang, Wei Chen, Shu-Qun Cheng, Dong Xie, Jing-Jing Li

Cell Mol Gastroenterol Hepatol. 2022; 14(1): 101–127. Published online 2022 Apr 4. doi: 10.1016/j.jcmgh.2022.03.009

PMCID:: PMC9117818

Abstract Article PDF–12M

Select item 903755413.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 889702214.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 849654115.

TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation

Hee-Seon Park, Ji-Won Song, Jin-Ho Park, Byung-Kwan Lim, Og-Sung Moon, Hwa-Young Son, Jae-Hyuk Lee, Bin Gao, Young-Suk Won, Hyo-Jung Kwon

Autophagy. 2021; 17(9): 2549–2564. Published online 2020 Nov 16. doi: 10.1080/15548627.2020.1834711

PMCID:: PMC8496541

Abstract Article PDF–19M

Select item 838659616.

DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy

Pietri Puustinen, Anne Keldsbo, Elisabeth Corcelle-Termeau, Kevin Ngoei, Stine L. Sønder, Thomas Farkas, Klaus Kaae Andersen, Jon S. Oakhill, Marja Jäättelä

Autophagy. 2020; 16(10): 1871–1888. Published online 2020 Jan 26. doi: 10.1080/15548627.2019.1710430

PMCID:: PMC8386596

Abstract Article PDF–5.7M

Select item 836418117.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 814454919.

Aerobic exercise intensity does not affect the anabolic signaling following resistance exercise in endurance athletes

T. W. Jones, L. Eddens, J. Kupusarevic, D. C. M. Simoes, M. J. W. Furber, K. A. van Someren, G. Howatson

Sci Rep. 2021; 11: 10785. Published online 2021 May 24. doi: 10.1038/s41598-021-90274-8

PMCID:: PMC8144549

Abstract Article PDF–1.4M

Select item 801210620.

An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis

Peng Zhao, Xiaoli Sun, Cynthia Chaggan, Zhongji Liao, Kai in Wong, Feng He, Seema Singh, Rohit Loomba, Michael Karin, Joseph L. Witztum, Alan R. Saltiel

Science. Author manuscript; available in PMC 2021 Mar 31.

Published in final edited form as: Science. 2020 Feb 7; 367(6478): 652–660. doi: 10.1126/science.aay0542

PMCID:: PMC8012106

Abstract Article PDF–2.5M

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