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Select item 103747581.

Long non-coding RNA HOTTIP exerts an oncogenic function by regulating HOXA13 in nasopharyngeal carcinoma

Huajun Feng, Feipeng Zhao, Jian Luo, Shengen Xu, Zhuoping Liang, Wei Xu, Yilin Bao, Gang Qin

Mol Biol Rep. 2023; 50(8): 6807–6818. Published online 2023 Jul 1. doi: 10.1007/s11033-023-08598-9

PMCID:: PMC10374758

Abstract Article PDF–712K

Select item 96913182.

A Computationally Constructed lncRNA-Associated Competing Triplet Network in Clear Cell Renal Cell Carcinoma

Hui Zhang, Qing Ye, Zixiang Chen, Chunyi Zhao, Qian Wu, Yuting Ding, Qixiang Shao, Yangjing Zhao

Dis Markers. 2022; 2022: 8928282. Published online 2022 Nov 17. doi: 10.1155/2022/8928282

PMCID:: PMC9691318

Abstract Article PDF–2.2M

Select item 89854303.

HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia

Huacheng Luo, Ganqian Zhu, Melanie A. Eshelman, Tsz Kan Fung, Qian Lai, Fei Wang, Bernd B. Zeisig, Julia Lesperance, Xiaoyan Ma, Shi Chen, Nicholas Cesari, Christopher Cogle, Baoan Chen, Bing Xu, Feng-Chun Yang, Chi Wai Eric So, Yi Qiu, Mingjiang Xu, Suming Huang

Mol Cell. Author manuscript; available in PMC 2022 Apr 6.

Published in final edited form as: Mol Cell. 2022 Feb 17; 82(4): 833–851.e11. doi: 10.1016/j.molcel.2022.01.014

PMCID:: PMC8985430

Abstract Article PDF–3.8M

Select item 88735654.

M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway

Huaili Jiang, Lei Zhou, Na Shen, Xianhui Ning, Daquan Wu, Kanglun Jiang, Xinsheng Huang

Cell Death Dis. 2022 Feb; 13(2): 183. Published online 2022 Feb 24. doi: 10.1038/s41419-022-04640-z

PMCID:: PMC8873565

Abstract Article PDF–8.1M

Select item 88107565.

Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1α/VEGF signaling

Huamei Wei, Zuoming Xu, Liucui Chen, Qing Wei, Zihua Huang, Guoman Liu, Wenchuan Li, Jianchu Wang, Qianli Tang, Jian Pu

Cell Death Dis. 2022 Feb; 13(2): 102. Published online 2022 Feb 2. doi: 10.1038/s41419-022-04505-5

PMCID:: PMC8810756

Abstract Article PDF–4.3M

Select item 88107346.

A coordinated function of lncRNA HOTTIP and miRNA-196b underpinning leukemogenesis by targeting FAS signaling

Ajeet P. Singh, Huacheng Luo, Meghana Matur, Melanie A. Eshelman, Karina Hamamoto, Arati Sharma, Julia Lesperance, Suming Huang

Oncogene. Author manuscript; available in PMC 2022 May 29.

Published in final edited form as: Oncogene. 2022 Jan; 41(5): 718–731. Published online 2021 Nov 29. doi: 10.1038/s41388-021-02127-3

PMCID:: PMC8810734

Abstract Article PDF–3.5M

Select item 82616237.

Long non-coding RNA HOTTIP enhances the fibrosis of lung tissues by regulating the miR-744-5p/PTBP1 signaling axis

Jing Li, Wenshu Chai, Zhuo Zhao, Yan Zhou, Qi Wu

Mol Med Rep. 2021 Sep; 24(3): 619. Published online 2021 Jun 30. doi: 10.3892/mmr.2021.12258

PMCID:: PMC8261623

Abstract Article PDF–7.0M

Select item 81568588.

The Influence of rs1859168 Polymorphism on Serum Expression of HOTTIP and Its Target miR-615-3p in Egyptian Patients with Breast Cancer

Omayma O. Abdelaleem, Olfat G. Shaker, Marwa N. AbdelHafez, Noha K. Abdelghaffar, Hanaa M. Eid, Mohamed Zaidan, Abeer A. Khalefa, Naglaa A. Ahmed, Nada F. Hemeda, Othman M. Zaki, Aeshah Ali A. Awaji, Shereen R. Mohammed

Biomolecules. 2021 May; 11(5): 733. Published online 2021 May 14. doi: 10.3390/biom11050733

PMCID:: PMC8156858

Abstract Article PDF–1.5M

Select item 80200849.

Knockdown of lncRNA HOTTIP Inhibits Retinoblastoma Progression by Modulating the miR-101-3p/STC1 Axis

XiangWen Yuan, Zhaoyan Sun, Congxian Cui

Technol Cancer Res Treat. 2021; 20: 1533033821997831. Published online 2021 Mar 31. doi: 10.1177/1533033821997831

PMCID:: PMC8020084

Abstract Article PDF–1.2M

Select item 788910310.

LncRNA HOTTIP facilitates cell proliferation, invasion, and migration in osteosarcoma by interaction with PTBP1 to promote KHSRP level

Xin-Yu Yao, Jian-Fan Liu, Yi Luo, Xue-Zheng Xu, Jie Bu

Cell Cycle. 2021; 20(3): 283–297. Published online 2021 Jan 21. doi: 10.1080/15384101.2020.1870820

PMCID:: PMC7889103

Abstract Article PDF–16M

Select item 780215711.

LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis

Xianwei He, Kun Gao, Shuaihua Lu, Rongbo Wu

BMC Musculoskelet Disord. 2021; 22: 67. Published online 2021 Jan 12. doi: 10.1186/s12891-020-03861-7

PMCID:: PMC7802157

Abstract Article PDF–3.7M

Select item 754145812.

SNP-SNP interactions of oncogenic long non-coding RNAs HOTAIR and HOTTIP on gastric cancer susceptibility

Esmat Abdi, Saeid Latifi-Navid, Saber Zahri, Vahid Kholghi-Oskooei, Behdad Mostafaiy, Abbas Yazdanbod, Farhad Pourfarzi

Sci Rep. 2020; 10: 16763. Published online 2020 Oct 7. doi: 10.1038/s41598-020-73682-0

PMCID:: PMC7541458

Abstract Article PDF–929K

Select item 753352213.

LncRNA HOTTIP promotes the proliferation and invasion of ovarian cancer cells by activating the MEK/ERK pathway

Jian Liu, Hong-Bo Hu, Yan-Ming Liu, Fan-Xiang Li, Liu-Ping Zhang, Zong-Min Liao

Mol Med Rep. 2020 Nov; 22(5): 3667–3676. Published online 2020 Aug 21. doi: 10.3892/mmr.2020.11452

PMCID:: PMC7533522

Abstract Article PDF–1.7M

Select item 741974614.

HOTTIP polymorphism may affect gastric cancer susceptibility by altering HOTTIP expression

Ben-gang Wang, Yi-zhi Li, Han-xi Ding, Zhi Lv, Qian Xu, Yuan Yuan

Biosci Rep. 2020 Aug 28; 40(8): BSR20191687. Published online 2020 Aug 11. doi: 10.1042/BSR20191687

PMCID:: PMC7419746

Abstract Article PDF–465K

Select item 729412315.

LncRNA HOTTIP facilitates the stemness of breast cancer via regulation of miR‐148a‐3p/WNT1 pathway

Li Han, Yuanyuan Yan, Lin Zhao, Yinuo Liu, Xuemei Lv, Liwen Zhang, Yanyun Zhao, Haishan Zhao, Miao He, Minjie Wei

J Cell Mol Med. 2020 Jun; 24(11): 6242–6252. Published online 2020 Apr 19. doi: 10.1111/jcmm.15261

PMCID:: PMC7294123

Abstract Article PDF–1.8M

Select item 691703516.

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Huacheng Luo, Ganqian Zhu, Jianfeng Xu, Qian Lai, Bowen Yan, Ying Guo, Tsz Kan Fung, Bernd B. Zeisig, Ya Cui, Jie Zha, Christopher Cogle, Fei Wang, Bing Xu, Feng-Chun Yang, Wei Li, Chi Wai Eric So, Yi Qiu, Mingjiang Xu, Suming Huang

Cancer Cell. Author manuscript; available in PMC 2020 Dec 9.

Published in final edited form as: Cancer Cell. 2019 Dec 9; 36(6): 645–659.e8. Published online 2019 Nov 27. doi: 10.1016/j.ccell.2019.10.011

PMCID:: PMC6917035

Abstract Article PDF–3.2M

Select item 677938117.

Low level of exosomal long non-coding RNA HOTTIP is a prognostic biomarker in colorectal cancer

Florian Oehme, Stefan Krahl, Balazs Gyorffy, Benjamin Muessle, Venkatesh Rao, Helena Greif, Nicole Ziegler, Kuailu Lin, May-Linn Thepkaysone, Heike Polster, Torsten Tonn, Martin Schneider, Juergen Weitz, Franziska Baenke, Christoph Kahlert

RNA Biol. 2019; 16(10): 1339–1345. Published online 2019 Jul 7. doi: 10.1080/15476286.2019.1637697