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Select item 111481841.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 110149172.

CKAP5 stabilizes CENP-E at kinetochores by regulating microtubule-chromosome attachments

R Bhagya Lakshmi, Pinaki Nayak, Linoy Raz, Apurba Sarkar, Akshay Saroha, Pratibha Kumari, Vishnu M Nair, Delvin P Kombarakkaran, S Sajana, Sanusha M G, Sarit S Agasti, Raja Paul, Uri Ben-David, Tapas K Manna

EMBO Rep. 2024 Apr; 25(4): 1909–1935. Published online 2024 Feb 29. doi: 10.1038/s44319-024-00106-9

PMCID:: PMC11014917

Abstract Article PDF–11M

Select item 106300893.

A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona

Jingchao Wu, Maximilian W.D. Raas, Paula Sobrevals Alcaraz, Harmjan R. Vos, Eelco C. Tromer, Berend Snel, Geert J.P.L. Kops

J Cell Biol. 2024 Jan 1; 223(1): e202303007. Published online 2023 Nov 7. doi: 10.1083/jcb.202303007

PMCID:: PMC10630089

Abstract Article PDF–7.9M

Select item 105658764.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104742975.

CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly

Susana Eibes, Girish Rajendraprasad, Claudia Guasch-Boldu, Mirela Kubat, Yulia Steblyanko, Marin Barisic

Nat Commun. 2023; 14: 5317. Published online 2023 Sep 1. doi: 10.1038/s41467-023-41091-2

PMCID:: PMC10474297

Abstract Article PDF–6.3M

Select item 99224686.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 93434557.

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis

Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi

Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y

PMCID:: PMC9343455

Abstract Article PDF–3.7M

Select item 91197368.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 88064319.

Centromere protein E as a novel biomarker and potential therapeutic target for retinoblastoma

Ke Shi, Xinyue Zhu, Jiali Wu, Yuhong Chen, Jingfa Zhang, Xiaodong Sun

Bioengineered. 2021; 12(1): 5950–5970. Published online 2021 Sep 5. doi: 10.1080/21655979.2021.1972080

PMCID:: PMC8806431

Abstract Article PDF–8.4M

Select item 852757810.

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity

Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang

Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008

PMCID:: PMC8527578

Abstract Article PDF–4.5M

Select item 836418111.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 816859812.

Poly-SUMO-2/3 chain modification of Nuf2 facilitates CENP-E kinetochore localization and chromosome congression during mitosis

Divya Subramonian, Te-An Chen, Nicholas Paolini, Xiang-Dong “David” Zhang

Cell Cycle. 2021; 20(9): 855–873. Published online 2021 Apr 28. doi: 10.1080/15384101.2021.1907509

PMCID:: PMC8168598

Abstract Article PDF–2.5M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 797975114.

A non-canonical function for Centromere-associated protein-E controls centrosome integrity and orientation of cell division

Mikito Owa, Brian Dynlacht

Commun Biol. 2021; 4: 358. Published online 2021 Mar 19. doi: 10.1038/s42003-021-01861-4

PMCID:: PMC7979751

Abstract Article PDF–5.0M

Select item 791940515.

Structure and comparison of the motor domain of centromere-associated protein E

Asuka Shibuya, Naohisa Ogo, Jun-ichi Sawada, Akira Asai, Hideshi Yokoyama

Acta Crystallogr D Struct Biol. 2021 Mar 1; 77(Pt 3): 280–287. Published online 2021 Feb 17. doi: 10.1107/S2059798321000176

PMCID:: PMC7919405

Abstract Article PDF–1.6M

Select item 778089216.

Kinesin Family Member C1 (KIFC1) Regulated by Centrosome Protein E (CENPE) Promotes Proliferation, Migration, and Epithelial-Mesenchymal Transition of Ovarian Cancer

Jiangning Li, Haidan Diao, Xin Guan, Xiaofang Tian

Med Sci Monit. 2020; 26: e927869-1–e927869-10. Prepublished online 2020 Oct 23. Published online 2020 Dec 28. doi: 10.12659/MSM.927869

PMCID:: PMC7780892

Abstract Article PDF–3.7M

Select item 768301517.

Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly

Xu Liu, Leilei Xu, Junying Li, Phil Y Yao, Wanjuan Wang, Hazrat Ismail, Haowei Wang, Bryce Liao, Zhihong Yang, Tarsha Ward, Ke Ruan, Jianchun Zhang, Quan Wu, Ping He, Xia Ding, Dongmei Wang, Chuanhai Fu, Zhen Dou, Feng Yan, Wenwen Wang, Xing Liu, Xuebiao Yao

J Mol Cell Biol. 2020 Aug; 12(8): 654–665. Published online 2019 Sep 10. doi: 10.1093/jmcb/mjz051

PMCID:: PMC7683015

Abstract Article PDF–2.1M

Select item 767585018.

CENPE, PRC1, TTK, and PLK4 May Play Crucial Roles in the Osteosarcoma Progression

Fei Wang, Qiheng Zhao, Wenping Liu, Daliang Kong

Technol Cancer Res Treat. 2020; 19: 1533033820973278. Published online 2020 Nov 11. doi: 10.1177/1533033820973278

PMCID:: PMC7675850

Abstract Article PDF–461K

Select item 761053519.

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase

Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Heinzlmeir, Christoph Sotriffer, Stefan Knapp, Elmar Wolf

Nat Chem Biol. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Nat Chem Biol. 2020 Nov 1; 16(11): 1179–1188. Published online 2020 Sep 28. doi: 10.1038/s41589-020-00652-y

PMCID:: PMC7610535

Abstract Article PDF–5.1M

Select item 677813720.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

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