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Select item 112181171.

Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity

Norihiro Tsuneyoshi, Tomonori Hosoya, Yuriko Takeno, Kodai Saitoh, Hidetaka Murai, Naoki Amimoto, Rie Tatsumi, Sono Watanabe, Yudai Hasegawa, Eri Kikkawa, Kumiko Goto, Fusako Nishigaki, Kouichi Tamura, Hironobu Kimura

Stem Cell Res Ther. 2024; 15: 193. Published online 2024 Jul 2. doi: 10.1186/s13287-024-03810-4

PMCID:: PMC11218117

Abstract Article PDF–1.9M

Select item 109911092.

An alternatively spliced PD-L1 isoform PD-L1∆3, and PD-L2 expression in breast cancers: implications for eligibility scoring and immunotherapy response

Didem Naz Dioken, Ibrahim Ozgul, Irem Yilmazbilek, Mustafa Cengiz Yakicier, Ezgi Karaca, Ayse Elif Erson-Bensan

Cancer Immunol Immunother. 2023 Dec; 72(12): 4065–4075. Published online 2023 Sep 28. doi: 10.1007/s00262-023-03543-y

PMCID:: PMC10991109

Abstract Article PDF–2.2M

Select item 105688793.

Cholinergic signaling influences the expression of immune checkpoint inhibitors, PD-L1 and PD-L2, and tumor hallmarks in human colorectal cancer tissues and cell lines

Nyanbol Kuol, Janusz Godlewski, Zbigniew Kmiec, Sara Vogrin, Sarah Fraser, Vasso Apostolopoulos, Kulmira Nurgali

BMC Cancer. 2023; 23: 971. Published online 2023 Oct 12. doi: 10.1186/s12885-023-11410-3

PMCID:: PMC10568879

Abstract Article PDF–10M

Select item 100606384.

Pan-cancer analysis identifies PD-L2 as a tumor promotor in the tumor microenvironment

Jingfang Lv, Zheng Jiang, Junhu Yuan, Meng Zhuang, Xu Guan, Hengchang Liu, Yefeng Yin, Yiming Ma, Zheng Liu, Hongying Wang, Xishan Wang

Front Immunol. 2023; 14: 1093716. Published online 2023 Mar 16. doi: 10.3389/fimmu.2023.1093716

PMCID:: PMC10060638

Abstract Article PDF–15M

Select item 100504155.

Evolving landscape of PD-L2: bring new light to checkpoint immunotherapy

Yuqing Wang, Jiang Du, Zhenyue Gao, Haoyang Sun, Mei Mei, Yu Wang, Yu Ren, Xuan Zhou

Br J Cancer. 2023 Mar 30; 128(7): 1196–1207. Published online 2022 Dec 15. doi: 10.1038/s41416-022-02084-y

PMCID:: PMC10050415

Abstract Article PDF–1.2M

Select item 99529486.

Expression of IDO1 and PD-L2 in Patients with Benign Lymphadenopathies and Association with Autoimmune Diseases

Maysaa Abdulla, Christer Sundström, Cecilia Lindskog, Peter Hollander

Biomolecules. 2023 Feb; 13(2): 240. Published online 2023 Jan 27. doi: 10.3390/biom13020240

PMCID:: PMC9952948

Abstract Article PDF–1.7M

Select item 96433737.

FAK promotes stromal PD-L2 expression associated with poor survival in pancreatic cancer

Catherine Davidson, David Taggart, Andrew H. Sims, David W. Lonergan, Marta Canel, Alan Serrels

Br J Cancer. 2022 Nov 9; 127(10): 1893–1905. Published online 2022 Sep 22. doi: 10.1038/s41416-022-01966-5

PMCID:: PMC9643373

Abstract Article PDF–2.5M

Select item 96327578.

Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations

Marthe Minderman, Avital Amir, Willem Kraan, Esther J. M. Schilder-Tol, Monique E. C. M. Oud, Cornelis G. Scheepstra, Arnold L. Noorduyn, Philip M. Kluin, Marie José Kersten, Marcel Spaargaren, Steven T. Pals

Blood. 2021 Sep 30; 138(13): 1194–1197. doi: 10.1182/blood.2021011366

PMCID:: PMC9632757

Article

Select item 95463579.

Exome sequencing identifies PD‐L2 as a potential predisposition gene for lymphoma

Jianming Shao, Lei Gao, Marco L. Leung, Bailey Gallinger, Cara Inglese, M. Stephen Meyn, Daniela Del Gaudio, Soma Das, Zejuan Li

Hematol Oncol. 2022 Aug; 40(3): 475–478. Published online 2022 May 29. doi: 10.1002/hon.3033

PMCID:: PMC9546357

Abstract Article PDF–625K

Select item 936118910.

High Expression of Programmed Death Ligand 1 and Programmed Death Ligand 2 in Ophthalmic Sebaceous Carcinoma: The Case for a Clinical Trial of Checkpoint Inhibitors

NATALIE WOLKOW, FREDERICK A. JAKOBIEC, AMIR H. AFROGHEH, SARA I. PAI, WILLIAM C. FAQUIN

Am J Ophthalmol. Author manuscript; available in PMC 2022 Aug 9.

Published in final edited form as: Am J Ophthalmol. 2020 Dec; 220: 128–139. Published online 2020 Jul 28. doi: 10.1016/j.ajo.2020.07.031

PMCID:: PMC9361189

Abstract Article PDF–1.1M

Select item 935720311.

Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance

Zhentao Yang, Yan Wang, Sixue Liu, Weixian Deng, Shirley H. Lomeli, Gatien Moriceau, James Wohlschlegel, Marco Piva, Roger S. Lo

Cancer Discov. 2022 Aug 5; 12(8): 1942–1959. Published online 2022 May 31. doi: 10.1158/2159-8290.CD-21-1463

PMCID:: PMC9357203

Abstract Article PDF–6.8M

Select item 897727412.

PD‐L1 and PD‐L2 expression in pancreatic ductal adenocarcinoma and their correlation with immune infiltrates and DNA damage response molecules

Yue Zhang, Xianlong Chen, Shengwei Mo, Heng Ma, Zhaohui Lu, Shuangni Yu, Jie Chen

J Pathol Clin Res. 2022 May; 8(3): 257–267. Published online 2022 Jan 17. doi: 10.1002/cjp2.259

PMCID:: PMC8977274

Abstract Article PDF–1.2M

Select item 892902913.

Regulation of Immunity in Clear Cell Renal Carcinoma: Role of PD-1, PD-L1, and PD-L2

Liudmila Spirina, Zahar Yurmazov, Evgeny Usynin, Irina Kondakova, Ekaterine Ladutko, Evgeny Choynzonov

Curr Issues Mol Biol. 2021 Sep; 43(2): 1072–1080. Published online 2021 Sep 6. doi: 10.3390/cimb43020076

PMCID:: PMC8929029

Abstract Article PDF–665K

Select item 886725814.

Differential expression of PD-L1 and PD-L2 is associated with the tumor microenvironment of TILs and M2 TAMs and tumor differentiation in non-small cell lung cancer

Ryota Sumitomo, Cheng-Long Huang, Masaaki Fujita, Hiroyuki Cho, Hiroshi Date

Oncol Rep. 2022 Apr; 47(4): 73. Published online 2022 Feb 15. doi: 10.3892/or.2022.8284

PMCID:: PMC8867258

Abstract Article PDF–2.6M

Select item 865641915.

Inhibition of PI3Kδ Differentially Regulates Poly I:C– and Human Metapneumovirus–Induced PD–L1 and PD–L2 Expression in Human Bronchial Epithelial Cells

Tomohiro Ogawa, Keiko Kan-o, Ayaka Shiota, Akitaka Fujita, Yumiko Ishii, Satoru Fukuyama, Koichiro Matsumoto

Front Immunol. 2021; 12: 767666. Published online 2021 Nov 25. doi: 10.3389/fimmu.2021.767666

PMCID:: PMC8656419

Abstract Article PDF–11M

Select item 864533816.

Phospho-β-catenin expression in primary and metastatic melanomas and in tumor-free visceral tissues, and associations with expression of PD-L1 and PD-L2.

Joel Pinczewski, Rebecca C. Obeng, Craig L. Slingluff, Jr., Victor H. Engelhard

Pathol Res Pract. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Pathol Res Pract. 2021 Aug; 224: 153527. Published online 2021 Jun 17. doi: 10.1016/j.prp.2021.153527

PMCID:: PMC8645338

Abstract Article PDF–2.0M

Select item 858391317.

Clinical and Prognostic Value of Antigen-Presenting Cells with PD-L1/PD-L2 Expression in Ovarian Cancer Patients

Anna Pawłowska, Agnieszka Kwiatkowska, Dorota Suszczyk, Agata Chudzik, Rafał Tarkowski, Bartłomiej Barczyński, Jan Kotarski, Iwona Wertel

Int J Mol Sci. 2021 Nov; 22(21): 11563. Published online 2021 Oct 26. doi: 10.3390/ijms222111563

PMCID:: PMC8583913

Abstract Article PDF–3.8M

Select item 854751318.

PD-L2 glycosylation promotes immune evasion and predicts anti-EGFR efficacy

Yiqi Xu, Zhenyue Gao, Ruxin Hu, Yuqing Wang, Yuhong Wang, Zheng Su, Xiaoyue Zhang, Jingxuan Yang, Mei Mei, Yu Ren, Min Li, Xuan Zhou

J Immunother Cancer. 2021; 9(10): e002699. Published online 2021 Oct 25. doi: 10.1136/jitc-2021-002699

PMCID:: PMC8547513

Abstract Article PDF–4.4M

Select item 820611319.

Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival

Masanori Oshi, Yoshihisa Tokumaru, Fernando A. Angarita, Lan Lee, Li Yan, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe

Sci Rep. 2021; 11: 12541. Published online 2021 Jun 15. doi: 10.1038/s41598-021-91897-7

PMCID:: PMC8206113

Abstract Article PDF–3.6M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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