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Items: 1 to 20 of 121

1.
GRK2–YAP signaling is implicated in pulmonary arterial hypertension development
Peng Ye, Yunfei Deng, Yue Gu, Pengfei Liu, Jie Luo, Jiangqin Pu, Jingyu Chen, Yu Huang, Nanping Wang, Yong Ji, Shaoliang Chen
Chin Med J (Engl) 2024 Apr 5; 137(7): 846–858. Published online 2024 Jan 19. doi: 10.1097/CM9.0000000000002946
PMCID:
PMC10997289
AbstractArticlePDF–13M
2.
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation
Marta Sánchez-Soto, Noelia M. Boldizsar, Kayla A. Schardien, Nora S. Madaras, Blair K. A. Willette, Laura R. Inbody, Christopher Dasaro, Amy E. Moritz, Julia Drube, Raphael S. Haider, R. Benjamin Free, Carsten Hoffman, David R. Sibley
Biomolecules. 2023 Oct; 13(10): 1552. Published online 2023 Oct 20. doi: 10.3390/biom13101552
PMCID:
PMC10605370
AbstractArticlePDF–6.3M
3.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
4.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
5.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
6.
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold
Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo
Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134
PMCID:
PMC9475462
AbstractArticlePDF–4.6M
7.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
8.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
9.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
10.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
11.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
12.
Mdm2-Mediated Downmodulation of GRK2 Restricts Centrosome Separation for Proper Chromosome Congression
Clara Reglero, Belén Ortiz del Castillo, Verónica Rivas, Federico Mayor, Jr., Petronila Penela
Cells. 2021 Apr; 10(4): 729. Published online 2021 Mar 25. doi: 10.3390/cells10040729
PMCID:
PMC8064503
AbstractArticlePDF–4.4M
13.
The Open Question of How GPCRs Interact with GPCR Kinases (GRKs)
M. Claire Cato, Yu-Chen Yen, Charnelle J. Francis, Kaely E. Elkins, Afzaal Shareef, Rachel Sterne-Marr, John J. G. Tesmer
Biomolecules. 2021 Mar; 11(3): 447. Published online 2021 Mar 17. doi: 10.3390/biom11030447
PMCID:
PMC8002388
AbstractArticlePDF–3.8M
14.
The short third intracellular loop and cytoplasmic tail of bitter taste receptors provide functionally relevant GRK phosphorylation sites in TAS2R14
Donghwa Kim, Maria Castaño, Lauren K. Lujan, Jung A. Woo, Stephen B. Liggett
J Biol Chem. 2021 Jan-Jun; 296: 100216. Published online 2021 Jan 16. doi: 10.1074/jbc.RA120.016056
PMCID:
PMC7949105
AbstractArticlePDF–1.8M
15.
GRKs and Epac1 Interaction in Cardiac Remodeling and Heart Failure
Marion Laudette, Karina Formoso, Frank Lezoualc’h
Cells. 2021 Jan; 10(1): 154. Published online 2021 Jan 14. doi: 10.3390/cells10010154
PMCID:
PMC7830799
AbstractArticlePDF–2.1M
16.
The Metabolic Role of GRK2 in Insulin Resistance and Associated Conditions
Daniela Sorriento, Maria Rosaria Rusciano, Valeria Visco, Antonella Fiordelisi, Federica Andrea Cerasuolo, Paolo Poggio, Michele Ciccarelli, Guido Iaccarino
Cells. 2021 Jan; 10(1): 167. Published online 2021 Jan 15. doi: 10.3390/cells10010167
PMCID:
PMC7830135
AbstractArticlePDF–1.6M
17.
Nitric Oxide and S-Nitrosylation in Cardiac Regulation: G Protein-Coupled Receptor Kinase-2 and β-Arrestins as Targets
Gizem Kayki-Mutlu, Walter J. Koch
Int J Mol Sci. 2021 Jan; 22(2): 521. Published online 2021 Jan 7. doi: 10.3390/ijms22020521
PMCID:
PMC7825736
AbstractArticlePDF–1.4M
18.
The PDZ Domain Protein SYNJ2BP Regulates GRK-Dependent Sst2A Phosphorylation and Downstream MAPK Signaling
Heather S Carr, Jeffrey T Chang, Jeffrey A Frost
Endocrinology. 2021 Feb; 162(2): bqaa229. Published online 2020 Dec 12. doi: 10.1210/endocr/bqaa229
PMCID:
PMC7799432
AbstractArticle
19.
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling
Michaela Bosakova, Sara P Abraham, Alexandru Nita, Eva Hruba, Marcela Buchtova, S Paige Taylor, Ivan Duran, Jorge Martin, Katerina Svozilova, Tomas Barta, Miroslav Varecha, Lukas Balek, Jiri Kohoutek, Tomasz Radaszkiewicz, Ganesh V Pusapati, Vitezslav Bryja, Eric T Rush, Isabelle Thiffault, Deborah A Nickerson, Michael J Bamshad, University of Washington Center for Mendelian Genomics, Rajat Rohatgi, Daniel H Cohn, Deborah Krakow, Pavel Krejci
EMBO Mol Med. 2020 Nov 6; 12(11): e11739. Published online 2020 Oct 14. doi: 10.15252/emmm.201911739
PMCID:
PMC7645380
AbstractArticlePDF–7.1M
20.
Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells
Thor C. Møller, Mie F. Pedersen, Jeffrey R. van Senten, Sofie D. Seiersen, Jesper M. Mathiesen, Michel Bouvier, Hans Bräuner-Osborne
Sci Rep. 2020; 10: 17395. Published online 2020 Oct 15. doi: 10.1038/s41598-020-73674-0
PMCID:
PMC7567791
AbstractArticlePDF–1.7M

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