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Select item 111617461.

Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4⁺ regulatory T cells by regulating IL2RA

Syed Bilal Ahmad Andrabi, Ubaid Ullah Kalim, Senthil Palani, Mohd Moin Khan, Meraj Hasan Khan, Jimmy Fagersund, Julius Orpana, Niklas Paulin, Kedar Batkulwar, Sini Junttila, Tanja Buchacher, Toni Grönroos, Lea Toikka, Tea Ammunet, Partho Sen, Matej Orešič, Venla Kumpulainen, Johanna E. E. Tuomisto, Rahul Sinha, Alexander Marson, Omid Rasool, Laura L. Elo, Riitta Lahesmaa

Proc Natl Acad Sci U S A. 2024 Jun 4; 121(23): e2315363121. Published online 2024 May 28. doi: 10.1073/pnas.2315363121

PMCID:: PMC11161746

Abstract Article PDF–1.1M

Select item 110389252.

The augmentation of lymphokine-activated killer activity following pulsing of human peripheral blood mononuclear cells with recombinant human interleukin-2

C. R. D. Carter, B. W. Hancock, R. C. Rees

Cancer Immunol Immunother. 1992 Jul; 35(4): 264–270. doi: 10.1007/BF01789333

PMCID:: PMC11038925

Abstract Article PDF–925K

Select item 110276833.

Aberrant peripheral blood CD4⁺ CD25⁺ FOXP3⁺ regulatory T cells/T helper-17 number is associated with the outcome of patients with lymphoma

Mehdi Dehghani, Mehdi Kalani, Hossein Golmoghaddam, Mani Ramzi, Nargess Arandi

Cancer Immunol Immunother. 2020 Sep; 69(9): 1917–1928. Published online 2020 May 8. doi: 10.1007/s00262-020-02591-y

PMCID:: PMC11027683

Abstract Article PDF–1.7M

Select item 109925904.

Prognostic value of preoperative soluble interleukin 2 receptor α as a novel immune biomarker in epithelial ovarian cancer

Hui Li, Miaofang Wu, Zhuna Wu, Jinxiao Liang, Lijuan Wang, Xi Yang, Zhongqiu Lin, Jing Li

Cancer Immunol Immunother. 2022 Jun; 71(6): 1519–1530. Published online 2021 Nov 1. doi: 10.1007/s00262-021-03092-2

PMCID:: PMC10992590

Abstract Article PDF–2.7M

Select item 108836255.

Interleukin gene polymorphisms and alopecia areata: A systematic review and meta-analysis

Zasia Hossain Tishe, Sanjana Shawkat, Meherun Nessa Popy, Ashfaq Ahmed, Sadia Biswas Mumu, Mohd Nazmul Hasan Apu, Md Shaki Mostaid

Medicine (Baltimore) 2024 Feb 23; 103(8): e37300. Published online 2024 Feb 23. doi: 10.1097/MD.0000000000037300

PMCID:: PMC10883625

Abstract Article PDF–2.2M

Select item 108270186.

Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population

Kursat Ozdilli, Hasan Mervan Aytac, Fatima Ceren Tuncel, Yasemin Oyaci, Mustafa Pehlivan, Sacide Pehlivan

Neurosciences (Riyadh) 2024 Jan; 29(1): 51–56. doi: 10.17712/nsj.2024.1.20230075

PMCID:: PMC10827018

Abstract Article PDF–527K

Select item 96335427.

A great disturbance in the force: IL-2 receptor defects disrupt immune homeostasis

Joseph D. Hernandez, Elena W.Y. Hsieh

Curr Opin Pediatr. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Curr Opin Pediatr. 2022 Dec 1; 34(6): 580–588. Published online 2022 Sep 27. doi: 10.1097/MOP.0000000000001181

PMCID:: PMC9633542

Abstract Article PDF–723K

Select item 95313498.

An association study of IL2RA polymorphisms with cerebral palsy in a Chinese population

Yimeng Qiao, Yangong Wang, Yiran Xu, Jin Zhang, Yu Su, Ye Cheng, Dan Bi, Juan Song, Lei Xia, Ming Li, Xiaoli Zhang, Dengna Zhu, Ting Wang, Jian Ding, Xiaoyang Wang, Changlian Zhu, Qinghe Xing

BMC Med Genomics. 2022; 15: 208. Published online 2022 Oct 4. doi: 10.1186/s12920-022-01350-5

PMCID:: PMC9531349

Abstract Article PDF–818K

Select item 95092779.

KIAA0101 and IL2RA Were Identified as Core Genes in Hormone-Resistant Nephropathy

Ying Chen, Shuyi Qian, Yinyin Chen, Kanghan Liu, Wei Yin, Xun Luo

Dis Markers. 2022; 2022: 6545266. Published online 2022 Sep 17. doi: 10.1155/2022/6545266

PMCID:: PMC9509277

Abstract Article PDF–2.9M

Select item 942411410.

Spatial analysis and CD25-expression identify regulatory T cells as predictors of a poor prognosis in colorectal cancer

Christian H. Bergsland, Marine Jeanmougin, Seyed H. Moosavi, Aud Svindland, Jarle Bruun, Arild Nesbakken, Anita Sveen, Ragnhild A. Lothe

Mod Pathol. 2022; 35(9): 1236–1246. Published online 2022 Apr 28. doi: 10.1038/s41379-022-01086-8

PMCID:: PMC9424114

Abstract Article PDF–3.4M

Select item 914448011.

Methylene Blue Is a Nonspecific Protein–Protein Interaction Inhibitor with Potential for Repurposing as an Antiviral for COVID-19

Sung-Ting Chuang, Henrietta Papp, Anett Kuczmog, Rebecca Eells, Jose M. Condor Capcha, Lina A. Shehadeh, Ferenc Jakab, Peter Buchwald

Pharmaceuticals (Basel) 2022 May; 15(5): 621. Published online 2022 May 18. doi: 10.3390/ph15050621

PMCID:: PMC9144480

Abstract Article PDF–2.5M

Select item 902575012.

Soluble IL-2R Levels at Baseline Predict the Development of Severe Respiratory Failure and Mortality in COVID-19 Patients

Nikolaos K. Gatselis, Vasiliki Lygoura, Aggeliki Lyberopoulou, George Giannoulis, Anna Samakidou, Antonia Vaiou, George Vatidis, Katerina Antoniou, Aggelos Stefos, Sarah Georgiadou, Dimitrios Sagris, Dafni Sveroni, Despoina Stergioula, Stella Gabeta, George Ntaios, George N. Dalekos

Viruses. 2022 Apr; 14(4): 787. Published online 2022 Apr 10. doi: 10.3390/v14040787

PMCID:: PMC9025750

Abstract Article PDF–589K

Select item 888827013.

Up-regulated serum levels of soluble CD25 and soluble CD163 in pediatric patients with SARS-CoV-2

Gehan Ahmed Mostafa, Hanan Mohamed Ibrahim, Abeer Al Sayed Shehab, Yasmin Gamal El Gendy, Dina Medhat Mohamed Aly, Ghada Abdel Haleem Shousha

Eur J Pediatr. 2022; 181(6): 2299–2309. Published online 2022 Mar 2. doi: 10.1007/s00431-022-04398-8

PMCID:: PMC8888270

Abstract Article PDF–987K

Select item 888060714.

Human IL-2Rɑ subunit binding modulation of IL-2 through a decline in electrostatic interactions: A computational and experimental approach

Arezoo Beig Parikhani, Kowsar Bagherzadeh, Rada Dehghan, Alireza Biglari, Mohammad Ali Shokrgozar, Farhad Riazi Rad, Sirous Zeinali, Yeganeh Talebkhan, Soheila Ajdary, Reza Ahangari Cohan, Mahdi Behdani

PLoS One. 2022; 17(2): e0264353. Published online 2022 Feb 25. doi: 10.1371/journal.pone.0264353

PMCID:: PMC8880607

Abstract Article PDF–3.5M

Select item 871369815.

Liver Injury and Elevated Levels of Interleukins, Interleukin-2 Receptor, and Interleukin-6 Predict the Severity in Patients With COVID-19

Kuan Luo, Yongfeng Chen, Junjie Yang, Quan Tao, Min Luo

Front Public Health. 2021; 9: 778340. Published online 2021 Dec 14. doi: 10.3389/fpubh.2021.778340

PMCID:: PMC8713698

Abstract Article PDF–367K

Select item 869514716.

系统性红斑狼疮患者血清白细胞介素-2受体α水平及其临床意义

田佳宜, 张霞, 程功, 刘庆红, 王世阳, 何菁

Beijing Da Xue Xue Bao Yi Xue Ban. 2021 Dec 18; 53(6): 1083–1087. Chinese. Published online 2021 Nov 15. doi: 10.19723/j.issn.1671-167X.2021.06.013

PMCID:: PMC8695147

Abstract Article PDF–1.0M

Select item 868445217.

A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling

Rimma Goldberg, Jennie N Clough, Luke B Roberts, Jenifer Sanchez, Shahram Kordasti, Nedyalko Petrov, Arnulf Hertweck, Anna Lorenc, Ian Jackson, Scott Tasker, Anna Appios, Omer Omer, Miles Parkes, Natalie Prescott, Richard G Jenner, Peter M Irving, Graham M Lord

J Crohns Colitis. 2021 Dec; 15(12): 2054–2065. Published online 2021 Jun 12. doi: 10.1093/ecco-jcc/jjab103

PMCID:: PMC8684452

Abstract Article PDF–1.3M

Select item 856915418.

Restoration of HBV-specific CD8⁺ T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-α therapy

Dongyao Wang, Binqing Fu, Xiaokun Shen, Chuang Guo, Yanyan Liu, Junfei Zhang, Rui Sun, Ying Ye, Jiabin Li, Zhigang Tian, Haiming Wei

Signal Transduct Target Ther. 2021; 6: 376. Published online 2021 Nov 5. doi: 10.1038/s41392-021-00776-0

PMCID:: PMC8569154

Abstract Article PDF–5.5M

Select item 845758319.

Blood transfusion practices affect CD4⁺ CD25⁺ FOXP3⁺ regulatory T cells/T helper-17 cells and the clinical outcome of geriatric patients with hip fracture

Ling Wang, Wei Chen, Fu-Biao Kang, Ya-Hui Zhang, Li-Li Qi, Ying-Ze Zhang

Aging (Albany NY) 2021 Sep 15; 13(17): 21408–21420. Published online 2021 Sep 1. doi: 10.18632/aging.203479

PMCID:: PMC8457583

Abstract Article PDF–1.8M

Select item 837907420.

Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis

Maria E. Joosse, Fabienne Charbit-Henrion, Remy Boisgard, Rolien (H.) C. Raatgeep, Dicky J. Lindenbergh-Kortleve, Léa M. M. Costes, Sandrine Nugteren, Nicolas Guegan, Marianna Parlato, Sharon Veenbergen, Valérie Malan, Jan K. Nowak, Iris H. I. M. Hollink, M. Luisa Mearin, Johanna C. Escher, Nadine Cerf-Bensussan, Janneke N. Samsom

Mucosal Immunol. 2021; 14(5): 1172–1182. Published online 2021 Jul 5. doi: 10.1038/s41385-021-00423-5

PMCID:: PMC8379074

Abstract Article PDF–6.2M

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PMC Links for GEO Profiles (Select 42548622) (233)
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Homo sapiens OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:124082573-124083571 (L...
Homo sapiens OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:124082573-124083571 (LOC127403698) on chromosome 5
gi|2325267861|ref|NG_105647.1|

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1000 Plant (1KP) Transcriptomes: The Remaining Data

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