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Items: 1 to 20 of 26

1.
The ubiquitin ligase TRIM21 regulates mutant p53 accumulation and gain of function in cancer
Juan Liu, Cen Zhang, Dandan Xu, Tianliang Zhang, Chun-Yuan Chang, Jianming Wang, Jie Liu, Lanjing Zhang, Bruce G. Haffty, Wei-Xing Zong, Wenwei Hu, Zhaohui Feng
J Clin Invest. 2023 Mar 15; 133(6): e164354. Published online 2023 Mar 15. doi: 10.1172/JCI164354
PMCID:
PMC10014102
AbstractArticlePDF–18M
2.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
E3 Ubiquitin Ligase UBR5 Promotes the Metastasis of Pancreatic Cancer via Destabilizing F-Actin Capping Protein CAPZA1
Jin Li, Wei Zhang, Jian Gao, Min Du, Huimin Li, Mengge Li, Hui Cong, Yuan Fang, Yiyi Liang, Dan Zhao, Gang Xiang, Xiaojing Ma, Ming Yao, Hong Tu, Yu Gan
Front Oncol. 2021; 11: 634167. Published online 2021 Mar 12. doi: 10.3389/fonc.2021.634167
Correction in:
Front Oncol. 2021; 11: 693855.
PMCID:
PMC7994773
AbstractArticlePDF–9.9M
5.
LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy
Yanke Chen, Ting Jiang, Hongyi Zhang, Xingchun Gou, Cong Han, Jianhui Wang, Ann T. Chen, Jun Ma, Jun Liu, Zeming Chen, Xintao Jing, Hong Lei, Zhenzhen Wang, Youmei Bao, Mehdi Baqri, Yong Zhu, Ranjit S. Bindra, James E. Hansen, Jun Dou, Chen Huang, Jiangbing Zhou
Nat Cell Biol. Author manuscript; available in PMC 2021 Apr 1.
Published in final edited form as: Nat Cell Biol. 2020 Oct; 22(10): 1276–1285. Published online 2020 Oct 1. doi: 10.1038/s41556-020-00586-6
PMCID:
PMC7962994
AbstractArticlePDF–5.5M
6.
TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT–GSK-3β–β-Catenin Signaling Pathway
Shiyu Chen, Zhiwei He, Changhao Zhu, Yanqing Liu, Lin Li, Lu Deng, Jun Wang, Chao Yu, Chengyi Sun
Front Oncol. 2020; 10: 554787. Published online 2020 Oct 16. doi: 10.3389/fonc.2020.554787
PMCID:
PMC7651862
AbstractArticlePDF–5.4M
7.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
8.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
9.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
10.
?F508 CFTR interactome remodeling promotes rescue of Cystic Fibrosis
Sandra Pankow, Casimir Bamberger, Diego Calzolari, Salvador Martínez-Bartolomé, Mathieu Lavallée-Adam, William E. Balch, John R. Yates, III
Nature. Author manuscript; available in PMC 2016 May 30.
Published in final edited form as: Nature. 2015 Dec 24; 528(7583): 510–516. Published online 2015 Nov 30. doi: 10.1038/nature15729
PMCID:
PMC4826614
AbstractArticlePDF–5.7M
11.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
12.
Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage
Romain Drissi, Marie-Line Dubois, Mélanie Douziech, François-Michel Boisvert
Mol Cell Proteomics. 2015 Jul; 14(7): 2002–2013. Published online 2015 May 11. doi: 10.1074/mcp.M115.048991
PMCID:
PMC4587322
AbstractArticlePDF–3.0M
13.
Characterizing WW Domain Interactions of Tumor Suppressor WWOX Reveals Its Association with Multiprotein Networks
Mohammad Abu-Odeh, Tomer Bar-Mag, Haiming Huang, TaeHyung Kim, Zaidoun Salah, Suhaib K. Abdeen, Marius Sudol, Dana Reichmann, Sachdev Sidhu, Philip M. Kim, Rami I. Aqeilan
J Biol Chem. 2014 Mar 28; 289(13): 8865–8880. Published online 2014 Feb 18. doi: 10.1074/jbc.M113.506790
PMCID:
PMC3979411
AbstractArticlePDF–3.0M
14.
Abundant expression of myosin heavy-chain IIB RNA in a subset of human masseter muscle fibres
Michael J. Horton, Carla A. Brandon, Terence J. Morris, Thomas W. Braun, Kenneth M. Yaw, James J. Sciote
Arch Oral Biol. Author manuscript; available in PMC 2013 Dec 3.
Published in final edited form as: Arch Oral Biol. 2001 Nov; 46(11): 1039–1050. doi: 10.1016/s0003-9969(01)00066-8
PMCID:
PMC3848045
AbstractArticlePDF–6.4M
15.
Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling
Jennifer E Bond, Trung Q Ho, Maria Angelica Selim, Cedric L Hunter, Edith V Bowers, Howard Levinson
Lab Invest. Author manuscript; available in PMC 2012 Jul 28.
Published in final edited form as: Lab Invest. 2011 Apr; 91(4): 499–508. Published online 2010 Nov 22. doi: 10.1038/labinvest.2010.181
PMCID:
PMC3407540
AbstractArticlePDF–1.7M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins
Tanja Scherrer, Christian Femmer, Ralph Schiess, Ruedi Aebersold, André P Gerber
Genome Biol. 2011; 12(1): R3. Published online 2011 Jan 13. doi: 10.1186/gb-2011-12-1-r3
PMCID:
PMC3091301
AbstractArticlePDF–1.3M
18.
Raftlin Is Involved in the Nucleocapture Complex to Induce Poly(I:C)-mediated TLR3 Activation
Ayako Watanabe, Megumi Tatematsu, Kazuko Saeki, Sachiko Shibata, Hiroaki Shime, Akihiko Yoshimura, Chikashi Obuse, Tsukasa Seya, Misako Matsumoto
J Biol Chem. 2011 Mar 25; 286(12): 10702–10711. Published online 2011 Jan 25. doi: 10.1074/jbc.M110.185793
PMCID:
PMC3060521
AbstractArticlePDF–4.2M
19.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
20.
Network organization of the human autophagy system
Christian Behrends, Mathew E. Sowa, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2011 Jan 1.
Published in final edited form as: Nature. 2010 Jul 1; 466(7302): 68–76. Published online 2010 Jun 20. doi: 10.1038/nature09204
PMCID:
PMC2901998
AbstractArticlePDF–1.4M

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