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Select item 109168661.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 98188393.

PTPRK, an EGFR Phosphatase, Is Decreased in CeD Biopsies and Intestinal Organoids

Merlin Nanayakkara, Claudia Bellomo, Francesca Furone, Mariantonia Maglio, Antonella Marano, Giuliana Lania, Monia Porpora, Martina Nicoletti, Salvatore Auricchio, Maria Vittoria Barone

Cells. 2023 Jan; 12(1): 115. Published online 2022 Dec 28. doi: 10.3390/cells12010115

PMCID:: PMC9818839

Abstract Article PDF–2.7M

Select item 98003334.

Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains

Iain M. Hay, Maria Shamin, Eve R. Caroe, Ahmed S.A. Mohammed, Dmitri I. Svergun, Cy M. Jeffries, Stephen C. Graham, Hayley J. Sharpe, Janet E. Deane

J Biol Chem. 2023 Jan; 299(1): 102750. Published online 2022 Nov 25. doi: 10.1016/j.jbc.2022.102750

PMCID:: PMC9800333

Abstract Article PDF–2.9M

Select item 94915715.

Investigation of cell signalings and therapeutic targets in PTPRK-RSPO3 fusion-positive colorectal cancer

Jae Heon Jeong, Jae Won Yun, Ha Young Kim, Chan Yeong Heo, Sejoon Lee

PLoS One. 2022; 17(9): e0274555. Published online 2022 Sep 21. doi: 10.1371/journal.pone.0274555

PMCID:: PMC9491571

Abstract Article PDF–2.2M

Select item 93485766.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92316237.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 85164138.

A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling

Minseong Kim, Carmen Reinhard, Christof Niehrs

eLife. 2021; 10: e70885. Published online 2021 Sep 30. doi: 10.7554/eLife.70885

PMCID:: PMC8516413

Abstract Article PDF–10M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 796055010.

USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease

Megan Perry, Meghan Biegert, Sai Sundeep Kollala, Halle Mallard, Grace Su, Manohar Kodavati, Natasha Kreiling, Alexander Holbrook, Gargi Ghosal

J Biol Chem. 2021 Jan-Jun; 296: 100396. Published online 2021 Feb 7. doi: 10.1016/j.jbc.2021.100396

PMCID:: PMC7960550

Abstract Article PDF–1.5M

Select item 765186211.

TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT–GSK-3β–β-Catenin Signaling Pathway

Shiyu Chen, Zhiwei He, Changhao Zhu, Yanqing Liu, Lin Li, Lu Deng, Jun Wang, Chao Yu, Chengyi Sun

Front Oncol. 2020; 10: 554787. Published online 2020 Oct 16. doi: 10.3389/fonc.2020.554787

PMCID:: PMC7651862

Abstract Article PDF–5.4M

Select item 720679312.

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler

Science. Author manuscript; available in PMC 2020 May 8.

Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812

PMCID:: PMC7206793

Abstract Article PDF–2.2M

Select item 699693213.

The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer

Ling-Shih Chang, Minseong Kim, Andrey Glinka, Carmen Reinhard, Christof Niehrs

eLife. 2020; 9: e51248. Published online 2020 Jan 14. doi: 10.7554/eLife.51248

PMCID:: PMC6996932

Abstract Article PDF–4.2M

Select item 651525314.

PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations

Monika Świerczewska, Karolina Sterzyńska, Karolina Wojtowicz, Dominika Kaźmierczak, Dariusz Iżycki, Michał Nowicki, Maciej Zabel, Radosław Januchowski

Int J Mol Sci. 2019 Apr; 20(8): 2053. Published online 2019 Apr 25. doi: 10.3390/ijms20082053

PMCID:: PMC6515253

Abstract Article PDF–13M

Select item 648771215.

PTPRK suppresses progression and chemo‐resistance of colon cancer cells via direct inhibition of pro‐oncogenic CD133

Masashi Matsushita, Yusuke Mori, Kyosuke Uchiumi, Takehiro Ogata, Mizuyo Nakamura, Hiroyuki Yoda, Hiroaki Soda, Nobuhiro Takiguchi, Yoshihiro Nabeya, Osamu Shimozato, Toshinori Ozaki

FEBS Open Bio. 2019 May; 9(5): 935–946. Published online 2019 Apr 18. doi: 10.1002/2211-5463.12636

PMCID:: PMC6487712

Abstract Article PDF–724K

Select item 644074416.

The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell–cell adhesion

Gareth W Fearnley, Katherine A Young, James R Edgar, Robin Antrobus, Iain M Hay, Wei-Ching Liang, Nadia Martinez-Martin, WeiYu Lin, Janet E Deane, Hayley J Sharpe

eLife. 2019; 8: e44597. Published online 2019 Mar 29. doi: 10.7554/eLife.44597

PMCID:: PMC6440744

Abstract Article PDF–4.5M

Select item 637480417.

Downregulation of PTPRK Promotes Cell Proliferation and Metastasis of NSCLC by Enhancing STAT3 Activation

Xuting Xu, Dong Li, Jin Liu, Zhihong Ma, Huilian Huang, Lishan Min, Licheng Dai, Shunli Dong

Anal Cell Pathol (Amst) 2019; 2019: 4265040. Published online 2019 Jan 29. doi: 10.1155/2019/4265040

PMCID:: PMC6374804

Abstract Article PDF–2.3M

Select item 619567818.

Analysis of PTPRK polymorphisms in association with risk and age at onset of Alzheimer’s disease, cancer risk, and cholesterol

Yang Chen, Chun Xu, Sam Harirforoosh, Xingguang Luo, Ke-Sheng Wang

J Psychiatr Res. Author manuscript; available in PMC 2018 Oct 20.

Published in final edited form as: J Psychiatr Res. 2018 Jan; 96: 65–72. Published online 2017 Sep 27. doi: 10.1016/j.jpsychires.2017.09.021

PMCID:: PMC6195678

Abstract Article PDF–512K

Select item 612538719.

RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation

Berta Casar, Andrew P. Badrock, Iñaki Jiménez, Imanol Arozarena, Paula Colón-Bolea, L. Francisco Lorenzo-Martín, Irene Barinaga-Rementería, Jorge Barriuso, Vincenzo Cappitelli, Daniel J. Donoghue, Xosé R. Bustelo, Adam Hurlstone, Piero Crespo

Nat Commun. 2018; 9: 3595. Published online 2018 Sep 5. doi: 10.1038/s41467-018-05941-8

PMCID:: PMC6125387

Abstract Article PDF–3.5M

Select item 583915820.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

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