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Items: 1 to 20 of 38

1.
RFX4 is an intrinsic factor for neuronal differentiation through induction of proneural genes POU3F2 and NEUROD1
Wonyoung Choi, Mu Seog Choe, Su Min Kim, So Jin Kim, Jiyeon Lee, Yeongun Lee, Sun-Min Lee, So Hee Dho, Min-Young Lee, Lark Kyun Kim
Cell Mol Life Sci. 2024 Dec; 81(1): 99. Published online 2024 Feb 22. doi: 10.1007/s00018-024-05129-y
PMCID:
PMC10884155
AbstractArticlePDF–6.0M
2.
CREB1 Facilitates GABAergic Neural Differentiation of Human Mesenchymal Stem Cells through BRN2 for Pain Alleviation and Locomotion Recovery after Spinal Cord Injury
Yanbing Kao, Hanming Zhu, Yu Yang, Wenyuan Shen, Wei Song, Renjie Zhang, Yanchun Liu, Haoyun Liu, Xiaohong Kong
Cells. 2024 Jan; 13(1): 67. Published online 2023 Dec 28. doi: 10.3390/cells13010067
PMCID:
PMC10778540
AbstractArticlePDF–9.8M
3.
Monoallelic intragenic POU3F2 variants lead to neurodevelopmental delay and hyperphagic obesity, confirming the gene’s candidacy in 6q16.1 deletions
Ria Schönauer, Wenjun Jin, Christin Findeisen, Irene Valenzuela, Laura Alice Devlin, Jill Murrell, Emma C. Bedoukian, Linda Pöschla, Elena Hantmann, Korbinian M. Riedhammer, Julia Hoefele, Konrad Platzer, Ronald Biemann, Philipp M. Campeau, Johannes Münch, Henrike Heyne, Anne Hoffmann, Adhideb Ghosh, Wenfei Sun, Hua Dong, Falko Noé, Christian Wolfrum, Emily Woods, Michael J. Parker, Ruxandra Neatu, Gwenael Le Guyader, Ange-Line Bruel, Laurence Perrin, Helena Spiewak, Genomics England Research Consortium, Isabelle Missotte, Melanie Fourgeaud, Vincent Michaud, Didier Lacombe, Sarah A. Paolucci, Jillian G. Buchan, Margaret Glissmeyer, Bernt Popp, Matthias Blüher, John A. Sayer, Jan Halbritter
Am J Hum Genet. 2023 Jun 1; 110(6): 998–1007. Published online 2023 May 18. doi: 10.1016/j.ajhg.2023.04.010
PMCID:
PMC10257002
AbstractArticlePDF–3.4M
4.
ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells
Zijie Gao, Jianye Xu, Yang Fan, Zongpu Zhang, Huizhi Wang, Mingyu Qian, Ping Zhang, Lin Deng, Jie Shen, Hao Xue, Rongrong Zhao, Teng Zhou, Xing Guo, Gang Li
J Exp Clin Cancer Res. 2022; 41: 323. Published online 2022 Nov 16. doi: 10.1186/s13046-022-02526-8
PMCID:
PMC9667586
AbstractArticlePDF–11M
5.
BRN2 is a non-canonical melanoma tumor-suppressor
Michael Hamm, Pierre Sohier, Valérie Petit, Jérémy H. Raymond, Véronique Delmas, Madeleine Le Coz, Franck Gesbert, Colin Kenny, Zackie Aktary, Marie Pouteaux, Florian Rambow, Alain Sarasin, Nisamanee Charoenchon, Alfonso Bellacosa, Luis Sanchez-del-Campo, Laura Mosteo, Martin Lauss, Dies Meijer, Eirikur Steingrimsson, Göran B. Jönsson, Robert A. Cornell, Irwin Davidson, Colin R. Goding, Lionel Larue
Nat Commun. 2021; 12: 3707. Published online 2021 Jun 17. doi: 10.1038/s41467-021-23973-5
PMCID:
PMC8211827
AbstractArticlePDF–1.9M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
8.
Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia
Chaodong Ding, Chunling Zhang, Richard Kopp, Liz Kuney, Qingtuan Meng, Le Wang, Yan Xia, Yi Jiang, Rujia Dai, Shishi Min, Wei-Dong Yao, Ma-Li Wong, Hongyu Ruan, Chunyu Liu, Chao Chen
Mol Psychiatry. Author manuscript; available in PMC 2021 Oct 13.
Published in final edited form as: Mol Psychiatry. 2021 Jul; 26(7): 3444–3460. Published online 2020 Sep 14. doi: 10.1038/s41380-020-00877-2
PMCID:
PMC7956165
AbstractArticlePDF–1.5M
9.
Transcriptome-wide transmission disequilibrium analysis identifies novel risk genes for autism spectrum disorder
Kunling Huang, Yuchang Wu, Junha Shin, Ye Zheng, Alireza Fotuhi Siahpirani, Yupei Lin, Zheng Ni, Jiawen Chen, Jing You, Sunduz Keles, Daifeng Wang, Sushmita Roy, Qiongshi Lu
PLoS Genet. 2021 Feb; 17(2): e1009309. Published online 2021 Feb 4. doi: 10.1371/journal.pgen.1009309
PMCID:
PMC7888619
AbstractArticlePDF–2.7M
10.
Epigenomic profiling discovers trans-lineage SOX2 partnerships driving tumor heterogeneity in lung squamous cell carcinoma
Takashi Sato, Seungyeul Yoo, Ranran Kong, Abhilasha Sinha, Prashanth Chandramani-Shivalingappa, Ayushi Patel, Maya Fridrikh, Osamu Nagano, Takashi Masuko, Mary Beth Beasley, Charles A. Powell, Jun Zhu, Hideo Watanabe
Cancer Res. Author manuscript; available in PMC 2020 Jun 15.
Published in final edited form as: Cancer Res. 2019 Dec 15; 79(24): 6084–6100. Published online 2019 Sep 24. doi: 10.1158/0008-5472.CAN-19-2132
PMCID:
PMC6911633
AbstractArticlePDF–4.0M
11.
BRN4 is a novel driver of neuroendocrine differentiation in castration-resistant prostate cancer and is selectively released in extracellular vesicles with BRN2
Divya Bhagirath, Thao Ly Yang, Z Laura Tabatabai, Shahana Majid, Rajvir Dahiya, Yuichiro Tanaka, Sharanjot Saini
Clin Cancer Res. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Clin Cancer Res. 2019 Nov 1; 25(21): 6532–6545. Published online 2019 Aug 1. doi: 10.1158/1078-0432.CCR-19-0498
PMCID:
PMC6825556
AbstractArticlePDF–924K
12.
POU3F2 is a regulator of a gene coexpression network in brain tissue from patients with neuropsychiatric disorders
Chao Chen, Qingtuan Meng, Yan Xia, Chaodong Ding, Le Wang, Rujia Dai, Lijun Cheng, Preethi Gunaratne, Richard A. Gibbs, Shishi Min, Cristian Coarfa, Jeffrey G. Reid, Chunling Zhang, Chuan Jiao, Yi Jiang, Gina Giase, Amber Thomas, Dominic Fitzgerald, Tonya Brunetti, Annie Shieh, Cuihua Xia, Yongjun Wang, Yunpeng Wang, Judith A. Badner, Elliot S. Gershon, Kevin P White, Chunyu Liu
Sci Transl Med. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: Sci Transl Med. 2018 Dec 19; 10(472): eaat8178. Published online 2018 Dec 13. doi: 10.1126/scitranslmed.aat8178
PMCID:
PMC6494100
AbstractArticlePDF–1.4M
13.
BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma
Katharine Herbert, Romuald Binet, Jean-Philippe Lambert, Pakavarin Louphrasitthiphol, Halime Kalkavan, Laura Sesma-Sanz, Carla Daniela Robles-Espinoza, Sovan Sarkar, Eda Suer, Sarah Andrews, Jagat Chauhan, Nicola D. Roberts, Mark R. Middleton, Anne-Claude Gingras, Jean-Yves Masson, Lionel Larue, Paola Falletta, Colin R. Goding
Genes Dev. 2019 Mar 1; 33(5-6): 310–332. doi: 10.1101/gad.314633.118
PMCID:
PMC6411009
AbstractArticlePDF–8.5M
14.
Capsaicin Inhibited Aggressive Phenotypes through Downregulation of Tumor-Associated NADH Oxidase (tNOX) by POU Domain Transcription Factor POU3F2
Hung Yen Chen, Yi Hui Lee, Huei Yu Chen, Chia An Yeh, Pin Ju Chueh, Yi-Mei J. Lin
Molecules. 2016 Jun; 21(6): 733. Published online 2016 Jun 4. doi: 10.3390/molecules21060733
PMCID:
PMC6273514
AbstractArticlePDF–4.9M
15.
NTF3 Is a Novel Target Gene of the Transcription Factor POU3F2 and Is Required for Neuronal Differentiation
Yi-Mei J. Lin, I-Lun Hsin, H. Sunny Sun, Shankung Lin, Yen-Ling Lai, Hsuan-Ying Chen, Ting-Yu Chen, Ya-Ping Chen, Yi-Ting Shen, Hung-Ming Wu
Mol Neurobiol. 2018; 55(11): 8403–8413. Published online 2018 Mar 16. doi: 10.1007/s12035-018-0995-y
PMCID:
PMC6153716
AbstractArticlePDF–4.7M
16.
Bi-allelic loss of CDKN2A initiates melanoma invasion via BRN2 activation
Hanlin Zeng, Aparna Jorapur, A. Hunter Shain, Ursula E. Lang, Rodrigo Torres, Yuntian Zhang, Andrew S. McNeal, Thomas Botton, Jue Lin, Matthew Donne, Ingmar N. Bastian, Richard Yu, Jeffrey P. North, Laura Pincus, Beth S. Ruben, Nancy M Joseph, Iwei Yeh, Boris C. Bastian, Robert L. Judson
Cancer Cell. Author manuscript; available in PMC 2019 Jul 9.
Published in final edited form as: Cancer Cell. 2018 Jul 9; 34(1): 56–68.e9. doi: 10.1016/j.ccell.2018.05.014
PMCID:
PMC6084788
AbstractArticlePDF–3.1M
17.
MITF and BRN2 contribute to metastatic growth after dissemination of melanoma
Jacinta L. Simmons, Carly J. Pierce, Fares Al-Ejeh, Glen M. Boyle
Sci Rep. 2017; 7: 10909. Published online 2017 Sep 7. doi: 10.1038/s41598-017-11366-y
PMCID:
PMC5589904
AbstractArticlePDF–7.4M
18.
NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF
Mitchell E. Fane, Yash Chhabra, David E.J. Hollingsworth, Jacinta L. Simmons, Loredana Spoerri, Tae Gyu Oh, Jagat Chauhan, Toby Chin, Lachlan Harris, Tracey J. Harvey, George E.O. Muscat, Colin R. Goding, Richard A Sturm, Nikolas K. Haass, Glen M. Boyle, Michael Piper, Aaron G. Smith
EBioMedicine. 2017 Feb; 16: 63–75. Published online 2017 Jan 16. doi: 10.1016/j.ebiom.2017.01.013
PMCID:
PMC5474438
AbstractArticlePDF–2.6M
19.
Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability
Paul R. Kasher, Katherine E. Schertz, Megan Thomas, Adam Jackson, Silvia Annunziata, María J. Ballesta-Martinez, Philippe M. Campeau, Peter E. Clayton, Jennifer L. Eaton, Tiziana Granata, Encarna Guillén-Navarro, Cristina Hernando, Caroline E. Laverriere, Agne Liedén, Olaya Villa-Marcos, Meriel McEntagart, Ann Nordgren, Chiara Pantaleoni, Céline Pebrel-Richard, Catherine Sarret, Francesca L. Sciacca, Ronnie Wright, Bronwyn Kerr, Eric Glasgow, Siddharth Banka
Am J Hum Genet. 2016 Feb 4; 98(2): 363–372. Published online 2016 Jan 28. doi: 10.1016/j.ajhg.2015.12.014
PMCID:
PMC4746363
AbstractArticlePDF–1.1M
20.
Systematic VCP-UBXD Adaptor Network Proteomics Identifies a Role for UBXN10 in Regulating Ciliogenesis
Malavika Raman, Mikhail Sergeev, Maija Garnaas, John R. Lydeard, Edward L. Huttlin, Wolfram Goessling, Jagesh V. Shah, J. Wade Harper
Nat Cell Biol. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: Nat Cell Biol. 2015 Oct; 17(10): 1356–1369. Published online 2015 Sep 21. doi: 10.1038/ncb3238
Correction in:
Nat Cell Biol. 2016 Mar; 18(3): 347.
PMCID:
PMC4610257
AbstractArticlePDF–4.5M

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