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Select item 106935361.

P2rx1 deficiency alleviates acetaminophen-induced acute liver failure by regulating the STING signaling pathway

Yeping Yu, Ling Chang, Qingluan Hu, Jianjun Zhu, Jianjun Zhang, Qiang Xia, Jie Zhao

Cell Biol Toxicol. 2023; 39(6): 2761–2774. Published online 2023 Apr 13. doi: 10.1007/s10565-023-09800-1

PMCID:: PMC10693536

Abstract Article PDF–11M

Select item 98980312.

P2X1 enhances leukemogenesis through PBX3-BCAT1 pathways

Xiaoxiao He, Yilu Xu, Dan Huang, Zhuo Yu, Jing Yu, Li Xie, Ligen Liu, Ye Yu, Chiqi Chen, Jiangbo Wan, Yaping Zhang, Junke Zheng

Leukemia. 2023; 37(2): 265–275. Published online 2022 Nov 23. doi: 10.1038/s41375-022-01759-y

PMCID:: PMC9898031

Abstract Article PDF–3.9M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699834.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67799165.

Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism

Karl E. Johansson, Anne-Lie Ståhl, Ida Arvidsson, Sebastian Loos, Ashmita Tontanahal, Johan Rebetz, Milan Chromek, Ann-Charlotte Kristoffersson, Ludger Johannes, Diana Karpman

Sci Rep. 2019; 9: 14362. Published online 2019 Oct 7. doi: 10.1038/s41598-019-50692-1

PMCID:: PMC6779916

Abstract Article PDF–1.7M

Select item 67300366.

Contribution of Calcium Ions to P2X Channel Responses

Terrance M. Egan, Baljit S. Khakh

J Neurosci. 2004 Mar 31; 24(13): 3413–3420. doi: 10.1523/JNEUROSCI.5429-03.2004

PMCID:: PMC6730036

Abstract Article PDF–420K

Select item 65476117.

Toxoplasma gondii ROP18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell P2X1

Li-Juan Zhou, Min Chen, Santhosh Puthiyakunnon, Cheng He, Jing Xia, Cynthia Y. He, Sheng-Qun Deng, Hong-Juan Peng

Parasit Vectors. 2019; 12: 284. Published online 2019 Jun 4. doi: 10.1186/s13071-019-3529-1

PMCID:: PMC6547611

Abstract Article PDF–9.0M

Select item 62601148.

P2X1 Receptors Amplify FcγRIIa-Induced Ca ²⁺ Increases and Functional Responses in Human Platelets

Zeki Ilkan, Stephanie Watson, Steve P. Watson, Martyn P. Mahaut-Smith

Thromb Haemost. 2018 Feb; 118(2): 369–380. Published online 2018 Jan 29. doi: 10.1160/TH17-07-0530

PMCID:: PMC6260114

Abstract Article PDF–563K

Select item 61666829.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 610213010.

Mapping the binding site of the P2X receptor antagonist PPADS reveals the importance of orthosteric site charge and the cysteine-rich head region

Hong Huo, Alistair G. Fryatt, Louise K. Farmer, Ralf Schmid, Richard J. Evans

J Biol Chem. 2018 Aug 17; 293(33): 12820–12831. Published online 2018 Jul 11. doi: 10.1074/jbc.RA118.003737

PMCID:: PMC6102130

Abstract Article PDF–2.6M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 464794112.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 427237113.

Vascular smooth muscle cells from small human omental arteries express P2X1 and P2X4 receptor subunits

Claire M. Nichols, Oleksandr V. Povstyan, Anthony P. Albert, Dmitry V. Gordienko, Omar Khan, Georgios Vasilikostas, Teck K. Khong, Andrew Wan, Marcus Reddy, Maksym I. Harhun

Purinergic Signal. 2014 Dec; 10(4): 565–572. Published online 2014 May 22. doi: 10.1007/s11302-014-9415-6