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Select item 109217391.

PLA2G4A and ACHE modulate lipid profiles via glycerophospholipid metabolism in platinum-resistant gastric cancer

Menglin Chen, Cancan Zhang, Huaizhi Li, Shanshan Zheng, Yaqi Li, Mengyun Yuan, Yuxuan Chen, Jian Wu, Qingmin Sun

J Transl Med. 2024; 22: 249. Published online 2024 Mar 7. doi: 10.1186/s12967-024-05055-4

PMCID:: PMC10921739

Abstract Article PDF–5.6M

Select item 106415242.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 94754533.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 93000634.

Genetic polymorphism data support a relationship between schizophrenia and microsatellite variability in PLA2G4A in Northern Europeans not Han Chinese

Craig J. Hudson, Adam M. R. Groh, Fabio Macciardi, Rhys C. Hudson

Am J Med Genet B Neuropsychiatr Genet. 2022 Jan-Feb; 189(1-2): 3–5. Published online 2021 Dec 9. doi: 10.1002/ajmg.b.32881

PMCID:: PMC9300063

Article PDF–456K

Select item 92792855.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 92021856.

Calcium-dependent cytosolic phospholipase A₂ activation is implicated in neuroinflammation and oxidative stress associated with ApoE4

Shaowei Wang, Boyang Li, Victoria Solomon, Alfred Fonteh, Stanley I. Rapoport, David A. Bennett, Zoe Arvanitakis, Helena C. Chui, Patrick M. Sullivan, Hussein N. Yassine

Mol Neurodegener. 2022; 17: 42. Published online 2022 Jun 15. doi: 10.1186/s13024-022-00549-5

PMCID:: PMC9202185

Abstract Article PDF–7.2M

Select item 91197367.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 88970228.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 87407449.

A synergy between mechanosensitive calcium- and membrane-binding mediates tension-sensing by C2-like domains

Zhouyang Shen, Kalina T. Belcheva, Mark Jelcic, King Lam Hui, Anushka Katikaneni, Philipp Niethammer

Proc Natl Acad Sci U S A. 2022 Jan 4; 119(1): e2112390119. Published online 2021 Dec 28. doi: 10.1073/pnas.2112390119

PMCID:: PMC8740744

Abstract Article PDF–1.3M

Select item 870599110.

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells

Nur Mahammad, Felicity J. Ashcroft, Astrid J. Feuerherm, Samah Elsaadi, Esten N. Vandsemb, Magne Børset, Berit Johansen

Molecules. 2021 Dec; 26(24): 7447. Published online 2021 Dec 9. doi: 10.3390/molecules26247447

PMCID:: PMC8705991

Abstract Article PDF–5.3M

Select item 855154211.

Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A₂s

Daiki Hayashi, Varnavas D. Mouchlis, Edward A. Dennis

J Lipid Res. 2021; 62: 100113. Published online 2021 Aug 30. doi: 10.1016/j.jlr.2021.100113

PMCID:: PMC8551542

Abstract Article PDF–2.0M

Select item 843101212.

A Multiplex CRISPR-Screen Identifies PLA2G4A as Prognostic Marker and Druggable Target for HOXA9 and MEIS1 Dependent AML

Jacob Jalil Hassan, Anna Lieske, Nicole Dörpmund, Denise Klatt, Dirk Hoffmann, Marc-Jens Kleppa, Olga S. Kustikova, Maike Stahlhut, Adrian Schwarzer, Axel Schambach, Tobias Maetzig

Int J Mol Sci. 2021 Sep; 22(17): 9411. Published online 2021 Aug 30. doi: 10.3390/ijms22179411

PMCID:: PMC8431012

Abstract Article PDF–2.8M

Select item 840999113.

PLA2G4A promotes right-sided colorectal cancer progression by inducing CD39+γδ Treg polarization

Yang Zhan, Lei Zheng, Jia Liu, Dongzhi Hu, Junfeng Wang, Kai Liu, Jiansheng Guo, Ti Zhang, Dalu Kong

JCI Insight. 2021 Aug 23; 6(16): e148028. Published online 2021 Aug 23. doi: 10.1172/jci.insight.148028

PMCID:: PMC8409991

Abstract Article PDF–13M

Select item 820610314.

Quantitative proteomics analysis of glioblastoma cell lines after lncRNA HULC silencing

Shan Ye, Jing Wu, Yiran Wang, Yuchen Hu, Tiantian Yin, Jie He

Sci Rep. 2021; 11: 12587. Published online 2021 Jun 15. doi: 10.1038/s41598-021-92089-z

PMCID:: PMC8206103

Abstract Article PDF–3.2M

Select item 811573815.

Re-analysis of genetic polymorphism data supports a relationship between schizophrenia and microsatellite variability in PLA2G4A

Craig J. Hudson, Justin X.G. Zhu, Alexandra M. Durocher

Psychiatr Genet. 2021 Jun; 31(3): 102–105. Published online 2021 Apr 12. doi: 10.1097/YPG.0000000000000280

PMCID:: PMC8115738

Article PDF–856K

Select item 808827416.

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch

Agnieszka T. Kawashima, Cassandra Wong, Gema Lordén, Charles C. King, Pablo Lara-Gonzalez, Arshad Desai, Anne-Claude Gingras, Alexandra C. Newton

Mol Cell Biol. 2021 Mar; 41(3): e00333-20. Prepublished online 2021 Jan 4. Published online 2021 Feb 23. doi: 10.1128/MCB.00333-20

PMCID:: PMC8088274

Abstract Article PDF–3.1M

Select item 760338617.

Updating Phospholipase A₂ Biology

Makoto Murakami, Hiroyasu Sato, Yoshitaka Taketomi

Biomolecules. 2020 Oct; 10(10): 1457. Published online 2020 Oct 19. doi: 10.3390/biom10101457

PMCID:: PMC7603386

Abstract Article PDF–2.3M

Select item 760004018.

cPLA₂α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation

Felicity J. Ashcroft, Nur Mahammad, Helene Midtun Flatekvål, Astrid J. Feuerherm, Berit Johansen

Biomolecules. 2020 Oct; 10(10): 1402. Published online 2020 Oct 2. doi: 10.3390/biom10101402

PMCID:: PMC7600040

Abstract Article PDF–2.1M

Select item 682384619.

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion

Calvin J. Chan, Roberta Le, Kaylan Burns, Khadra Ahmed, Etienne Coyaud, Estelle M. N. Laurent, Brian Raught, Paul Melançon

Mol Cell Proteomics. 2019 Nov; 18(11): 2285–2297. Published online 2019 Sep 13. doi: 10.1074/mcp.RA119.001645

PMCID:: PMC6823846

Abstract Article PDF–2.2M

Select item 666388020.

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4

Kyojiro N. Ikeda, Matthew Freeman

J Biol Chem. 2019 Jul 26; 294(30): 11486–11497. Published online 2019 Jun 7. doi: 10.1074/jbc.RA118.007074

PMCID:: PMC6663880

Abstract Article PDF–2.0M

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