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Select item 112280491.

Role of the V2R–βarrestin–Gβγ complex in promoting G protein translocation to endosomes

Badr Sokrat, Anthony H. Nguyen, Alex R. B. Thomsen, Li-Yin Huang, Hiroyuki Kobayashi, Alem W. Kahsai, Jihee Kim, Bing X. Ho, Symon Ma, John Little, IV, Catherine Ehrhart, Ian Pyne, Emmery Hammond, Michel Bouvier

Commun Biol. 2024; 7: 826. Published online 2024 Jul 7. doi: 10.1038/s42003-024-06512-y

PMCID:: PMC11228049

Abstract Article PDF–9.2M

Select item 93571662.

Exploiting dependence of castration-resistant prostate cancer on the arginine vasopressin signaling axis by repurposing vaptans

Laine M. Heidman, Nahuel Peinetti, Valeria A. Copello, Kerry L. Burnstein

Mol Cancer Res. Author manuscript; available in PMC 2023 Feb 5.

Published in final edited form as: Mol Cancer Res. 2022 Aug 5; 20(8): 1295–1304. doi: 10.1158/1541-7786.MCR-21-0927

PMCID:: PMC9357166

Abstract Article PDF–704K

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80750694.

ARGININE VASOPRESSIN RECEPTOR 2 ACTIVATION PROMOTES MICROVASCULAR PERMEABILITY IN SEPSIS

Ernesto Lopez, Satoshi Fukuda, Katalin Modis, Osamu Fujiwara, Baigal Enkhtaivan, Raul Trujillo-Abarca, Koji Ihara, Francisco Lima-Lopez, Dannelys Perez-Bello, Csaba Szabo, Donald S. Prough, Perenlei Enkhbaatar

Pharmacol Res. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Pharmacol Res. 2021 Jan; 163: 105272. Published online 2020 Nov 4. doi: 10.1016/j.phrs.2020.105272

PMCID:: PMC8075069

Abstract Article PDF–1.3M

Select item 80626325.

Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2

Qing-Tao He, Peng Xiao, Shen-Ming Huang, Ying-Li Jia, Zhong-Liang Zhu, Jing-Yu Lin, Fan Yang, Xiao-Na Tao, Ru-Jia Zhao, Feng-Yuan Gao, Xiao-Gang Niu, Kun-Hong Xiao, Jiangyun Wang, Changwen Jin, Jin-Peng Sun, Xiao Yu

Nat Commun. 2021; 12: 2396. Published online 2021 Apr 22. doi: 10.1038/s41467-021-22731-x

PMCID:: PMC8062632

Abstract Article PDF–3.5M

Select item 75996096.

AQP2: Mutations Associated with Congenital Nephrogenic Diabetes Insipidus and Regulation by Post-Translational Modifications and Protein-Protein Interactions

Chao Gao, Paul J. Higgins, Wenzheng Zhang

Cells. 2020 Oct; 9(10): 2172. Published online 2020 Sep 26. doi: 10.3390/cells9102172

PMCID:: PMC7599609

Abstract Article PDF–837K

Select item 75324667.

Characterization of five novel vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus reveals a role of tolvaptan for M272R-V2R mutation

Federica Prosperi, Yoko Suzumoto, Pierluigi Marzuillo, Vincenzo Costanzo, Sabina Jelen, Anna Iervolino, Stefano Guarino, Angela La Manna, Emanuele Miraglia Del Giudice, Alessandra F. Perna, Miriam Zacchia, Emmanuelle Cordat, Giovambattista Capasso, Francesco Trepiccione

Sci Rep. 2020; 10: 16383. Published online 2020 Oct 2. doi: 10.1038/s41598-020-73089-x

PMCID:: PMC7532466

Abstract Article PDF–4.8M

Select item 74608948.

Epithelial Vasopressin Type-2 Receptors Regulate Myofibroblasts by a YAP-CCN2–Dependent Mechanism in Polycystic Kidney Disease

Nidhi Dwivedi, Shixin Tao, Abeda Jamadar, Sonali Sinha, Christianna Howard, Darren P. Wallace, Timothy A. Fields, Andrew Leask, James P. Calvet, Reena Rao

J Am Soc Nephrol. 2020 Aug; 31(8): 1697–1710. Published online 2020 Jun 17. doi: 10.1681/ASN.2020020190

PMCID:: PMC7460894

Abstract Article

Select item 73493599.

The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation

Marianna Ranieri, Maria Venneri, Tommaso Pellegrino, Mariangela Centrone, Annarita Di Mise, Susanna Cotecchia, Grazia Tamma, Giovanna Valenti

Cells. 2020 Jun; 9(6): 1354. Published online 2020 May 29. doi: 10.3390/cells9061354

PMCID:: PMC7349359

Abstract Article PDF–3.4M

Select item 727262310.

Vasopressin receptor 2 mutations in the nephrogenic syndrome of inappropriate antidiuresis show different mechanisms of constitutive activation for G protein coupled receptors

Vanessa Vezzi, Caterina Ambrosio, Maria Cristina Grò, Paola Molinari, Gökçe Süral, Tommaso Costa, H. Ongun Onaran, Susanna Cotecchia

Sci Rep. 2020; 10: 9111. Published online 2020 Jun 4. doi: 10.1038/s41598-020-65996-w

PMCID:: PMC7272623

Abstract Article PDF–4.0M

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 678317112.

Identification of a novel X-linked arginine-vasopressin receptor 2 mutation in nephrogenic diabetes insipidus: Case report and pedigree analysis

Danxia Peng, Ying Dai, Xuan Xu

Medicine (Baltimore) 2019 Oct; 98(40): e17359. Published online 2019 Oct 4. doi: 10.1097/MD.0000000000017359

PMCID:: PMC6783171

Abstract Article PDF–1.0M

Select item 656146713.

A novel AVPR2 splice site mutation leads to partial X-linked nephrogenic diabetes insipidus in two brothers

Marie Helene Schernthaner-Reiter, David Adams, Giampaolo Trivellin, Mary Scott Ramnitz, Margarita Raygada, Gretchen Golas, Fabio Rueda Faucz, Lars Ola Nilsson, Aikaterini A. Nella, Kavitha Dileepan, Maya Lodish, Paul Lee, Cynthia Tifft, Thomas Markello, William Gahl, Constantine A. Stratakis

Eur J Pediatr. Author manuscript; available in PMC 2019 Jun 12.

Published in final edited form as: Eur J Pediatr. 2016 May; 175(5): 727–733. Published online 2016 Jan 21. doi: 10.1007/s00431-015-2684-4

PMCID:: PMC6561467

Abstract Article PDF–306K

Select item 628033214.

A Novel Mutation in the AVPR2 Gene Causing Congenital Nephrogenic Diabetes Insipidus

Aslı Çelebi Tayfur, Tuğçe Karaduman, Merve Özcan Türkmen, Dilara Şahin, Aysun Çaltık Yılmaz, Bahar Büyükkaragöz, Ayşe Derya Buluş, Hatice Mergen

J Clin Res Pediatr Endocrinol. 2018 Dec; 10(4): 350–356. Published online 2018 Nov 29. doi: 10.4274/jcrpe.0097

PMCID:: PMC6280332

Abstract Article PDF–932K

Select item 588156915.

Identification, Characterization and Rescue of a Novel Vasopressin-2 Receptor Mutation Causing Nephrogenic Diabetes Insipidus

Sayali A. Ranadive, Baran Ersoy, Helene Favre, Clement C. Cheung, Stephen M. Rosenthal, Walter L. Miller, Christian Vaisse

Clin Endocrinol (Oxf) Author manuscript; available in PMC 2018 Apr 3.

Published in final edited form as: Clin Endocrinol (Oxf). 2009 Sep; 71(3): 388–393. Published online 2008 Dec 18. doi: 10.1111/j.1365-2265.2008.03513.x

PMCID:: PMC5881569

Abstract Article PDF–683K

Select item 579739316.

Contiguous 22.1-kb deletion embracing AVPR2 and ARHGAP4 genes at novel breakpoints leads to nephrogenic diabetes insipidus in a Chinese pedigree

Ying Bai, Yibing Chen, Xiangdong Kong

BMC Nephrol. 2018; 19: 26. Published online 2018 Feb 2. doi: 10.1186/s12882-018-0825-5

PMCID:: PMC5797393

Abstract Article PDF–816K

Select item 571335417.

Hereditary Nephrogenic Diabetes Insipidus: Pathophysiology and Possible Treatment. An Update

Serena Milano, Monica Carmosino, Andrea Gerbino, Maria Svelto, Giuseppe Procino

Int J Mol Sci. 2017 Nov; 18(11): 2385. Published online 2017 Nov 10. doi: 10.3390/ijms18112385

PMCID:: PMC5713354

Abstract Article PDF–2.1M

Select item 553655918.

A novel AVPR2 gene mutation of X-linked congenital nephrogenic diabetes insipidus in an Asian pedigree

Wei-Hong Guo, Qiang Li, Hong-Yan Wei, Hong-Yan Lu, Hui-Qi Qu, Mei Zhu

J Int Med Res. 2016 Oct; 44(5): 1131–1137. Published online 2016 Aug 25. doi: 10.1177/0300060516655642

PMCID:: PMC5536559

Abstract Article PDF–331K

Select item 541485119.

Altered Agonist Sensitivity of a Mutant V2 Receptor Suggests a Novel Therapeutic Strategy for Nephrogenic Diabetes Insipidus

László Sándor Erdélyi, András Balla, Attila Patócs, Miklós Tóth, Péter Várnai, László Hunyady

Mol Endocrinol. 2014 May; 28(5): 634–643. Published online 2014 Mar 14. doi: 10.1210/me.2013-1424

PMCID:: PMC5414851

Abstract Article

Select item 534018420.

Nephrogenic Syndrome of Inappropriate Antidiuresis

Brian J. Feldman, Stephen M. Rosenthal, Gabriel A. Vargas, Raymond G. Fenwick, Eric A. Huang, Mina Matsuda-Abedini, Robert H. Lustig, Robert S. Mathias, Anthony A. Portale, Walter L. Miller, Stephen E. Gitelman

N Engl J Med. Author manuscript; available in PMC 2017 Mar 7.

Published in final edited form as: N Engl J Med. 2005 May 5; 352(18): 1884–1890. doi: 10.1056/NEJMoa042743

PMCID:: PMC5340184

Abstract Article PDF–499K

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