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Select item 109332671.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 109050872.

Aberrant MNX1 expression associated with t(7;12)(q36;p13) pediatric acute myeloid leukemia induces the disease through altering histone methylation

Ahmed Waraky, Anders Östlund, Tina Nilsson, Dieter Weichenhan, Pavlo Lutsik, Marion Bähr, Joschka Hey, Gürcan Tunali, Jenni Adamsson, Susanna Jacobsson, Mohammad Hamdy Abdelrazak Morsy, Susann Li, Linda Fogelstrand, Christoph Plass, Lars Palmqvist

Haematologica. 2024 Mar 1; 109(3): 725–739. Published online 2023 Jun 15. doi: 10.3324/haematol.2022.282255

PMCID:: PMC10905087

Abstract Article PDF–2.8M

Select item 96887233.

Pan-Cancer Analysis Identifies MNX1 and Associated Antisense Transcripts as Biomarkers for Cancer

Denise Ragusa, Sabrina Tosi, Cristina Sisu

Cells. 2022 Nov; 11(22): 3577. Published online 2022 Nov 11. doi: 10.3390/cells11223577

PMCID:: PMC9688723

Abstract Article PDF–6.7M

Select item 95453344.

An induced pluripotent stem cell t(7;12)(q36;p13) acute myeloid leukemia model shows high expression of MNX1 and a block in differentiation of the erythroid and megakaryocytic lineages

Tina Nilsson, Ahmed Waraky, Anders Östlund, Susann Li, Anna Staffas, Julia Asp, Linda Fogelstrand, Jonas Abrahamsson, Lars Palmqvist

Int J Cancer. 2022 Sep 1; 151(5): 770–782. Published online 2022 Jun 3. doi: 10.1002/ijc.34122

PMCID:: PMC9545334

Abstract Article PDF–5.9M

Select item 88288955.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 80090486.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 78938917.

Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation

Emilia Solomon, Katie Davis-Anderson, Blake Hovde, Sofiya Micheva-Viteva, Jennifer Foster Harris, Scott Twary, Rashi Iyer

BMC Mol Cell Biol. 2021; 22: 13. Published online 2021 Feb 18. doi: 10.1186/s12860-021-00343-z

PMCID:: PMC7893891

Abstract Article PDF–1.5M

Select item 78482648.

lncRNA MNX1-AS1 Promotes Glioblastoma Progression Through Inhibition of miR-4443

Yan Gao, Yongchuan Xu, Jue Wang, Xue Yang, Lulu Wen, Juan Feng

Oncol Res. 2019; 27(3): 341–347. Published online 2019 Feb 21. doi: 10.3727/096504018X15228909735079

PMCID:: PMC7848264

Abstract Article PDF–3.0M

Select item 73100259.

Novel MNX1 mutations and genotype–phenotype analysis of patients with Currarino syndrome

Lu Han, Zhen Zhang, Hui Wang, Hui Song, Qing Gao, Yuchun Yan, Ran Tao, Ping Xiao, Long Li, Qian Jiang, Qi Li

Orphanet J Rare Dis. 2020; 15: 155. Published online 2020 Jun 22. doi: 10.1186/s13023-020-01442-4

PMCID:: PMC7310025

Abstract Article PDF–1.5M

Select item 671629610.

Motor Neuron and Pancreas Homeobox 1 (MNX1) Is Involved in Promoting Squamous Cervical Cancer Proliferation via Regulating Cyclin E

Li Xiao, Li Hong, Wenfei Zheng

Med Sci Monit. 2019; 25: 6304–6312. Published online 2019 Aug 22. doi: 10.12659/MSM.914233

PMCID:: PMC6716296

Abstract Article PDF–2.1M

Select item 653538711.

Upregulated expression of MNX1-AS1 long noncoding RNA predicts poor prognosis in gastric cancer

Wei Zhang, Lunhua Huang, Xinyang Lu, Kecheng Wang, Xiaofei Ning, Zhiqiang Liu

Bosn J Basic Med Sci. 2019 May; 19(2): 164–171. doi: 10.17305/bjbms.2019.3713

PMCID:: PMC6535387

Abstract Article PDF–1.0M

Select item 631203412.

The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells

Deborah Ingenhag, Sven Reister, Franziska Auer, Sanil Bhatia, Sarah Wildenhain, Daniel Picard, Marc Remke, Jessica I. Hoell, Andreas Kloetgen, Dennis Sohn, Reiner U. Jänicke, Gesine Koegler, Arndt Borkhardt, Julia Hauer

Haematologica. 2019 Jan; 104(1): 35–46. Prepublished online 2018 Aug 9. doi: 10.3324/haematol.2018.189407

PMCID:: PMC6312034

Abstract Article PDF–2.1M

Select item 616668213.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 610270714.

MNX1 reduces sensitivity to anoikis by activating TrkB in human glioma cells

Lai Jiang, Shaojun Chen, Donggang Zhao, Jun Yan, Jiemin Chen, Chunlin Yang, Gang Zheng

Mol Med Rep. 2018 Sep; 18(3): 3271–3279. Published online 2018 Jul 27. doi: 10.3892/mmr.2018.9329

PMCID:: PMC6102707

Abstract Article PDF–1.7M

Select item 582006915.

Spectrum of MNX1 Pathogenic Variants and Associated Clinical Features in Korean Patients with Currarino Syndrome

Seungjun Lee, Eun Jin Kim, Sung Im Cho, Hyunwoong Park, Soo Hyun Seo, Moon-Woo Seong, Sung Sup Park, Sung-Eun Jung, Seong-Cheol Lee, Kwi-Won Park, Hyun-Young Kim

Ann Lab Med. 2018 May; 38(3): 242–248. Published online 2018 Feb 2. doi: 10.3343/alm.2018.38.3.242

PMCID:: PMC5820069

Abstract Article PDF–384K

Select item 567858116.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 555931717.

RGS12 is a novel tumor suppressor gene in African American prostate cancer that represses AKT and MNX1 expression

Yongquan Wang, Jianghua Wang, Li Zhang, Omer Faruk Karatas, Longjiang Shao, Yiqun Zhang, Patricia Castro, Chad J. Creighton, Michael Ittmann

Cancer Res. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4247–4257. Published online 2017 Jun 13. doi: 10.1158/0008-5472.CAN-17-0669

PMCID:: PMC5559317

Abstract Article PDF–1.1M

Select item 509804118.

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions

Charles A. S. Banks, Gina Boanca, Zachary T. Lee, Cassandra G. Eubanks, Gaye L. Hattem, Allison Peak, Lauren E. Weems, Juliana J. Conkright, Laurence Florens, Michael P. Washburn

Mol Cell Proteomics. 2016 Nov; 15(11): 3435–3449. Published online 2016 Sep 8. doi: 10.1074/mcp.M116.060509

PMCID:: PMC5098041

Abstract Article PDF–2.1M

Select item 509306419.

MNX1 is oncogenically upregulated in African-American prostate cancer

Li Zhang, Jianghua Wang, Yongquan Wang, Yiqun Zhang, Patricia Castro, Longjiang Shao, Arun Sreekumar, Nagireddy Putluri, Nilanjan Guha, Saligrama Deepak, Arunkumar Padmanaban, Chad J. Creighton, Michael Ittmann

Cancer Res. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Cancer Res. 2016 Nov 1; 76(21): 6290–6298. Published online 2016 Aug 30. doi: 10.1158/0008-5472.CAN-16-0087