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Items: 1 to 20 of 372

1.
Validation of a novel NGS based BCR::ABL1 kinase domain mutation detection assay in Indian cohort
Pooja Chaudhary, Spandan Chaudhary, Falguni Patel, Shiv Patel, Toral Vaishnani, Nikha Trivedi, Dhiren Patel, Tushar Sonagara, Ashish Hirapara, Kavisha Vyas, Lokesh Patel, Raja Kumar, Nikkan Chakraborty, Divya Sharma, Jigar Suthar, Payal Kamdar, Ekta Jajodia, Firoz Ahmad, Neeraj Arora
Sci Rep. 2024; 14: 15745. Published online 2024 Jul 8. doi: 10.1038/s41598-024-66310-8
PMCID:
PMC11231265
AbstractArticlePDF–1.6M
2.
Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer
Yuria Mano, Koji Takahashi, Nobuhisa Ishikawa, Atsushi Takano, Wataru Yasui, Kouki Inai, Hitoshi Nishimura, Eiju Tsuchiya, Yusuke Nakamura, Yataro Daigo
Cancer Sci. 2007 Dec; 98(12): 1902–1913. Published online 2007 Sep 20. doi: 10.1111/j.1349-7006.2007.00610.x
PMCID:
PMC11159412
AbstractArticlePDF–688K
3.
Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway
Eman Hefni, Deepak Menon, Tao Ma, Emmanuel B. Asiedu, Ahmed Sultan, Timothy Meiller, Abraham Schneider, Akrit Sodhi, Silvia Montaner
Cell Signal. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Cell Signal. 2023 Aug; 108: 110697. Published online 2023 May 9. doi: 10.1016/j.cellsig.2023.110697
PMCID:
PMC11129037
AbstractArticlePDF–1.6M
4.
Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL
Lorenz Bastian, Thomas Beder, Malwine J. Barz, Sonja Bendig, Lorenz Bartsch, Wencke Walter, Nadine Wolgast, Björn Brändl, Christian Rohrandt, Björn-Thore Hansen, Alina M. Hartmann, Katharina Iben, Dennis Das Gupta, Miriam Denker, Johannes Zimmermann, Michael Wittig, Guranda Chitadze, Martin Neumann, Folker Schneller, Walter Fiedler, Björn Steffen, Matthias Stelljes, Christoph Faul, Stefan Schwartz, Franz-Josef Müller, Gunnar Cario, Lana Harder, Claudia Haferlach, Heike Pfeifer, Nicola Gökbuget, Monika Brüggemann, Claudia D. Baldus
Blood. 2024 Apr 4; 143(14): 1391–1398. Published online 2023 Dec 30. doi: 10.1182/blood.2023021752
PMCID:
PMC11033585
AbstractArticle
5.
Spectrum of BCR-ABL mutations in Azerbaijanian imatinib-resistant patients with chronic myeloid leukemia
Aypara Hasanova, Chingiz Asadov, Nigar Karimova, Aytan Shirinova, Gunay Aliyeva, Zohra Alimirzoyeva
Pathol Oncol Res. 2023; 29: 1611518. Published online 2023 Dec 22. doi: 10.3389/pore.2023.1611518
PMCID:
PMC10766836
AbstractArticlePDF–1.1M
6.
Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS
Helena Motaln, Urša Čerček, Alfred Yamoah, Priyanka Tripathi, Eleonora Aronica, Anand Goswami, Boris Rogelj
Brain. 2023 Oct; 146(10): 4088–4104. Published online 2023 Apr 18. doi: 10.1093/brain/awad130
PMCID:
PMC10545532
AbstractArticlePDF–2.0M
7.
Emergence of BCR-ABL Kinase Domain Mutations Associated with Newly Diagnosed Chronic Myeloid Leukemia: A Meta-Analysis of Clinical Trials of Tyrosine Kinase Inhibitors
Iulia D. Ursan, Ruixuan Jiang, Evan M. Pickard, Todd A. Lee, Daniel Ng, A. Simon Pickard
J Manag Care Spec Pharm. 2015 Feb; 21(2): 10.18553/jmcp.2015.21.2.114. Published online 2015 Oct 16. doi: 10.18553/jmcp.2015.21.2.114
PMCID:
PMC10397741
AbstractArticlePDF–284K
8.
The interplay between telomeric complex members and BCR::ABL1 oncogenic tyrosine kinase in the maintenance of telomere length in chronic myeloid leukemia
Anna Deręgowska, Monika Pępek, Iwona Solarska, Marcin M. Machnicki, Katarzyna Pruszczyk, Marek Dudziński, Joanna Niesiobędzka-Krężel, Ilona Seferyńska, Waldemar Sawicki, Maciej Wnuk, Tomasz Stokłosa
J Cancer Res Clin Oncol. 2023; 149(10): 7103–7112. Published online 2023 Mar 5. doi: 10.1007/s00432-023-04662-w
PMCID:
PMC10374722
AbstractArticlePDF–3.1M
9.
Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions
Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164
PMCID:
PMC10333884
AbstractArticlePDF–5.0M
10.
ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1
Benjamin Mayro, Jacob P. Hoj, Christian G. Cerda-Smith, Haley M. Hutchinson, Michael W. Caminear, Hannah L. Thrash, Peter S. Winter, Suzanne E. Wardell, Donald P. McDonnell, Colleen Wu, Kris C. Wood, Ann Marie Pendergast
Proc Natl Acad Sci U S A. 2023 Apr 18; 120(16): e2210418120. Published online 2023 Apr 11. doi: 10.1073/pnas.2210418120
PMCID:
PMC10120083
AbstractArticlePDF–4.2M
11.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
12.
Targeting the PTP1B‐Bcr‐Abl1 interaction for the degradation of T315I mutant Bcr‐Abl1 in chronic myeloid leukemia
Ahmed Elgehama, Yixuan Wang, Ying Yu, Lin Zhou, Zhixiu Chen, Liwei Wang, Lijun Sun, Jian Gao, Biao Yu, Yan Shen, Qiang Xu
Cancer Sci. 2023 Jan; 114(1): 247–258. Published online 2022 Sep 26. doi: 10.1111/cas.15580
PMCID:
PMC9807508
AbstractArticlePDF–4.3M
13.
c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation
Saebom Lee, Hye Guk Ryu, Sin Ho Kweon, Hyerynn Kim, Hyeonwoo Park, Kyung-Ha Lee, Sang-Min Jang, Chan Hyun Na, Sangjune Kim, Han Seok Ko
Cells. 2022 Dec; 11(24): 3972. Published online 2022 Dec 8. doi: 10.3390/cells11243972
PMCID:
PMC9776721
AbstractArticlePDF–2.9M
14.
Roles for c-Abl in postoperative neurodegeneration
Long Feng, Shihui Fu, Yao Yao, Yulong Li, Longhe Xu, Yali Zhao, Leiming Luo
Int J Med Sci. 2022; 19(12): 1753–1761. Published online 2022 Sep 28. doi: 10.7150/ijms.73740
PMCID:
PMC9608039
AbstractArticlePDF–440K
15.
Molecular profile reveals immune-associated markers of medulloblastoma for different subtypes
Jinyi Chen, Zhuang Kang, Shenglan Li, Can Wang, Xiaohong Zheng, Zehao Cai, Lexin Pan, Feng Chen, Wenbin Li
Front Immunol. 2022; 13: 911260. Published online 2022 Jul 28. doi: 10.3389/fimmu.2022.911260
PMCID:
PMC9367478
AbstractArticlePDF–20M
16.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
17.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
18.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
19.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
20.
Molecular classification improves risk assessment in adult BCR-ABL1–negative B-ALL
Elisabeth Paietta, Kathryn G. Roberts, Victoria Wang, Zhaohui Gu, Georgina A. N. Buck, Deqing Pei, Cheng Cheng, Ross L. Levine, Omar Abdel-Wahab, Zhongshan Cheng, Gang Wu, Chunxu Qu, Lei Shi, Stanley Pounds, Cheryl L. Willman, Richard Harvey, Janis Racevskis, Jan Barinka, Yanming Zhang, Gordon W. Dewald, Rhett P. Ketterling, David Alejos, Hillard M. Lazarus, Selina M. Luger, Letizia Foroni, Bela Patel, Adele K. Fielding, Ari Melnick, David I. Marks, Anthony V. Moorman, Peter H. Wiernik, Jacob M. Rowe, Martin S. Tallman, Anthony H. Goldstone, Charles G. Mullighan, Mark R. Litzow
Blood. 2021 Sep 16; 138(11): 948–958. Prepublished online 2021 Apr 25. doi: 10.1182/blood.2020010144
PMCID:
PMC9069478
AbstractArticle

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