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Items: 1 to 20 of 39

1.
WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination
Jie Zhang, Yuanyuan Yu, Xiuqun Zou, Yaning Du, Qiankun Liang, Mengyao Gong, Yurong He, Junqi Luo, Dandan Wu, Xiaoli Jiang, Matt Sinclair, Emad Tajkhorshid, Hong-Zhuan Chen, Zhaoyuan Hou, Yuejuan Zheng, Lin-Feng Chen, Xiao-Dong Yang
Nucleic Acids Res. 2024 May 22; 52(9): 4969–4984. Published online 2024 Mar 7. doi: 10.1093/nar/gkae161
PMCID:
PMC11109945
AbstractArticlePDF–1.6M
2.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
3.
WSB1 Involvement in Prostate Cancer Progression
Laura Boldrini, Massimo Bardi
Genes (Basel) 2023 Aug; 14(8): 1558. Published online 2023 Jul 29. doi: 10.3390/genes14081558
PMCID:
PMC10454498
AbstractArticlePDF–785K
4.
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions
Jiayi Chen, Mei Li, Yeqing Liu, Tangming Guan, Xiao Yang, Yalei Wen, Yingjie Zhu, Zeyu Xiao, Xiangchun Shen, Haoxing Zhang, Hui Tang, Tongzheng Liu
Cell Death Differ. 2023 Apr; 30(4): 1082–1095. Published online 2023 Feb 23. doi: 10.1038/s41418-023-01128-x
PMCID:
PMC10070344
AbstractArticlePDF–5.0M
5.
WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit
Xiaomeng Gao, Jieqiong You, Yanling Gong, Meng Yuan, Haiying Zhu, Liang Fang, Hong Zhu, Meidan Ying, Qiaojun He, Bo Yang, Ji Cao
Acta Pharm Sin B. 2022 Mar; 12(3): 1225–1239. Published online 2021 Oct 26. doi: 10.1016/j.apsb.2021.10.021
PMCID:
PMC9072231
AbstractArticlePDF–2.9M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
WSB1 and IL21R Genetic Variants Are Involved in Th2 Immune Responses to Ascaris lumbricoides
Valdirene Leão Carneiro, Hugo Bernardino Ferreira da Silva, Gerson de Almeida Queiroz, Rafael Valente Veiga, Pablo Rafael Silveira Oliveira, Norma Vilany Queiroz Carneiro, Anaque de Oliveira Pires, Raimon Rios da Silva, Flavia Sena, Emilia Belitardo, Regina Nascimento, Milca Silva, Cintia Rodrigues Marques, Ryan dos Santos Costa, Neuza Maria Alcantra-Neves, Mauricio L. Barreto, Philip J. Cooper, Camila Alexandrina Figueiredo
Front Immunol. 2021; 12: 622051. Published online 2021 Feb 22. doi: 10.3389/fimmu.2021.622051
PMCID:
PMC7937724
AbstractArticlePDF–1009K
8.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
9.
Deubiquitylase OTUD6B Governs pVHL Stability in an Enzyme‐Independent Manner and Suppresses Hepatocellular Carcinoma Metastasis
Xinxin Liu, Xiaoli Zhang, Zhiqiang Peng, Chunnan Li, Ze Wang, Chanjuan Wang, Zhikang Deng, Bo Wu, Yu Cui, Zhanxin Wang, Chun‐Ping Cui, Min Zheng, Lingqiang Zhang
Adv Sci (Weinh) 2020 Apr; 7(8): 1902040. Published online 2020 Mar 8. doi: 10.1002/advs.201902040
PMCID:
PMC7175249
AbstractArticlePDF–4.0M
10.
ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection
Ruth Hüttenhain, Jiewei Xu, Lily A. Burton, David E. Gordon, Judd F. Hultquist, Jeffrey R. Johnson, Laura Satkamp, Joseph Hiatt, David Y. Rhee, Kheewoong Baek, David C. Crosby, Alan D. Frankel, Alexander Marson, J. Wade Harper, Arno F. Alpi, Brenda A. Schulman, John D. Gross, Nevan J. Krogan
Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 10.
Published in final edited form as: Cell Host Microbe. 2019 Jul 10; 26(1): 86–99.e7. Published online 2019 Jun 25. doi: 10.1016/j.chom.2019.05.008
PMCID:
PMC7153695
AbstractArticlePDF–2.6M
11.
Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance
Matthew F Pech, Linda E Fong, Jacqueline E Villalta, Leanne JG Chan, Samir Kharbanda, Jonathon J O'Brien, Fiona E McAllister, Ari J Firestone, Calvin H Jan, Jeffrey Settleman
eLife. 2019; 8: e47362. Published online 2019 Aug 27. doi: 10.7554/eLife.47362
PMCID:
PMC6713475
AbstractArticlePDF–4.6M
12.
CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia
Qing-Yun Wu, Yuan-Yuan Zhu, Yang Liu, Fang Wei, Yu-Xue Tong, Jiang Cao, Ping Zhou, Ming-Shan Niu, Zhen-Yu Li, Ling-Yu Zeng, Feng Li, Kai-Lin Xu
Cell Death Dis. 2018 Jul; 9(7): 774. Published online 2018 Jul 10. doi: 10.1038/s41419-018-0812-6
PMCID:
PMC6039501
AbstractArticlePDF–2.7M
13.
WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer
Flore-Anne Poujade, Aarren Mannion, Nicholas Brittain, Andrew Theodosi, Ellie Beeby, Katarzyna B. Leszczynska, Ester M. Hammond, John Greenman, Christopher Cawthorne, Isabel M. Pires
Br J Cancer. 2018 May 1; 118(9): 1229–1237. Published online 2018 Mar 15. doi: 10.1038/s41416-018-0056-3
PMCID:
PMC5943535
AbstractArticlePDF–1.4M
14.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation
Jung Jin Kim, Seung Baek Lee, Sang-Yeop Yi, Sang-Ah Han, Sun-Hyun Kim, Jong-Min Lee, Seo-Yun Tong, Ping Yin, Bowen Gao, Jun Zhang, Zhenkun Lou
Cell Res. 2017 Feb; 27(2): 274–293. Published online 2016 Dec 13. doi: 10.1038/cr.2016.148
PMCID:
PMC5339850
AbstractArticlePDF–7.2M
17.
miR-592/WSB1/HIF-1α axis inhibits glycolytic metabolism to decrease hepatocellular carcinoma growth
Yan-Yan Jia, Jin-Yi Zhao, Bing-Ling Li, Kai Gao, Ying Song, Mei-You Liu, Xiao-Juan Yang, Yan Xue, Ai-Dong Wen, Lei Shi
Oncotarget. 2016 Jun 7; 7(23): 35257–35269. Published online 2016 May 2. doi: 10.18632/oncotarget.9135
PMCID:
PMC5085226
AbstractArticlePDF–7.9M
18.
WSB1: from homeostasis to hypoxia
Moinul Haque, Joseph Keith Kendal, Ryan Matthew MacIsaac, Douglas James Demetrick
J Biomed Sci. 2016; 23: 61. Published online 2016 Aug 19. doi: 10.1186/s12929-016-0270-3
PMCID:
PMC4992216
AbstractArticlePDF–1.5M
19.
Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1
Frederick C. Nucifora, Jr, Leslie G. Nucifora, Chee-Hoe Ng, Nicolas Arbez, Yajuan Guo, Elaine Roby, Vered Shani, Simone Engelender, Dong Wei, Xiao-Fang Wang, Tianxia Li, Darren J. Moore, Olga Pletnikova, Juan C. Troncoso, Akira Sawa, Ted M. Dawson, Wanli Smith, Kah-Leong Lim, Christopher A. Ross
Nat Commun. 2016; 7: 11792. Published online 2016 Jun 7. doi: 10.1038/ncomms11792
PMCID:
PMC4899630
AbstractArticlePDF–1.3M
20.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle

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