PMC Links for GEO Profiles (Select 4684926) - PMC

Links from GEO Profiles

Items: 1 to 20 of 84

<< First< Prev

Page of 5

Select item 106684451.

Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome

Xiao-Yue Chen, Ching Kao, Syue-Wei Peng, Jer-Hwa Chang, Yueh-Lun Lee, Vincent Laiman, Kian Fan Chung, Pankaj K. Bhavsar, Didik Setyo Heriyanto, Kai-Jen Chuang, Hsiao-Chi Chuang

Mol Med. 2023; 29: 159. Published online 2023 Nov 23. doi: 10.1186/s10020-023-00760-0

PMCID:: PMC10668445

Abstract Article PDF–4.6M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101085333.

Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling

Heshu Liu, Rui Yan, Zeru Xiao, Xuying Huang, Jiannan Yao, Jian Liu, Guangyu An, Yang Ge

Breast Cancer Res. 2023; 25: 43. Published online 2023 Apr 17. doi: 10.1186/s13058-023-01642-3

PMCID:: PMC10108533

Abstract Article PDF–14M

Select item 98520634.

Doublecortin-like kinase 1 is a therapeutic target in squamous cell carcinoma

David Standing, Levi Arnold, Prasad Dandawate, Brendan Ottemann, Vusala Snyder, Sivapriya Ponnurangam, Afreen Sayed, Dharmalingam Subramaniam, Pugazhendhi Srinivasan, Sonali Choudhury, Jacob New, Deep Kwatra, Prabhu Ramamoorthy, Badal C. Roy, Melissa Shadoin, Raed Al-Rajabi, Maura O’Neil, Sumedha Gunewardena, John Ashcraft, Shahid Umar, Scott J. Weir, Ossama Tawfik, Subhash B. Padhye, Bernhard Biersack, Shrikant Anant, Sufi Mary Thomas

Mol Carcinog. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Mol Carcinog. 2023 Feb; 62(2): 145–159. Published online 2022 Oct 11. doi: 10.1002/mc.23472

Correction in:: Mol Carcinog. 2023 Jun 21

PMCID:: PMC9852063

Abstract Article PDF–1.1M

Select item 94726195.

Targeting Doublecortin-Like Kinase 1 (DCLK1)-Regulated SARS-CoV-2 Pathogenesis in COVID-19

Ram Babu Undi, Jason L. Larabee, Adrian Filiberti, Susanna Ulahannan, Sheeja Aravindan, Edana Stroberg, Lisa M. Barton, Eric J. Duval, Sanjay Mukhopadhyay, James C. Henthorn, Darrin Akins, Courtney W. Houchen, Mark M. Huycke, Naushad Ali

J Virol. 2022 Sep; 96(17): e00967-22. Published online 2022 Aug 9. doi: 10.1128/jvi.00967-22

PMCID:: PMC9472619

Abstract Article PDF–6.4M

Select item 93485766.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 93305377.

DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis

Jee-Heun Kim, So-Yeon Park, So-El Jeon, Jang-Hyun Choi, Choong-Jae Lee, Tae-Young Jang, Hyeon-Ji Yun, Yuno Lee, Pilho Kim, Sang Hee Cho, Ji Shin Lee, Jeong-Seok Nam

Theranostics. 2022; 12(12): 5258–5271. Published online 2022 Jul 4. doi: 10.7150/thno.72037

PMCID:: PMC9330537

Abstract Article PDF–3.8M

Select item 90760118.

Targeting DCLK1 overcomes 5‐fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β‐catenin pathway‐mediated cancer stemness

Lanqing Wang, Lei Zhao, Zhenyu Lin, Dandan Yu, Min Jin, Pengfei Zhou, Jinghua Ren, Jing Cheng, Kunyu Yang, Gang Wu, Tao Zhang, Dejun Zhang

Clin Transl Med. 2022 May; 12(5): e743. Published online 2022 May 6. doi: 10.1002/ctm2.743

PMCID:: PMC9076011

Abstract Article PDF–5.2M

Select item 88570499.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 874895810.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 845269011.

Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1

Onisha Patel, Michael J. Roy, Ashleigh Kropp, Joshua M. Hardy, Weiwen Dai, Isabelle S. Lucet

Commun Biol. 2021; 4: 1105. Published online 2021 Sep 20. doi: 10.1038/s42003-021-02631-y

PMCID:: PMC8452690

Abstract Article PDF–2.9M

Select item 838611212.

Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer

Yang Ge, Nathaniel Weygant, Dongfeng Qu, Randal May, William L. Berry, Jiannan Yao, Parthasarathy Chandrakesan, Wei Zheng, Lichao Zhao, Karena L. Zhao, Michael Drake, Kenneth J. Vega, Michael S. Bronze, James J. Tomasek, Guangyu An, Courtney W. Houchen

Int J Cancer. Author manuscript; available in PMC 2021 Aug 25.

Published in final edited form as: Int J Cancer. 2018 Sep 1; 143(5): 1162–1175. Published online 2018 Apr 16. doi: 10.1002/ijc.31400

PMCID:: PMC8386112

Abstract Article PDF–2.7M

Select item 835259713.

Autoregulatory control of microtubule binding in doublecortin-like kinase 1

Regina L Agulto, Melissa M Rogers, Tracy C Tan, Amrita Ramkumar, Ashlyn M Downing, Hannah Bodin, Julia Castro, Dan W Nowakowski, Kassandra M Ori-McKenney

eLife. 2021; 10: e60126. Published online 2021 Jul 26. doi: 10.7554/eLife.60126

PMCID:: PMC8352597

Abstract Article PDF–2.3M

Select item 828563514.

MicroRNA-195 regulates Tuft cell function in the intestinal epithelium by altering translation of DCLK1

Min S. Kwon, Hee K. Chung, Lan Xiao, Ting-Xi Yu, Shelley R. Wang, Jun-Jie Piao, Jaladanki N. Rao, Myriam Gorospe, Jian-Ying Wang

Am J Physiol Cell Physiol. 2021 Jun 1; 320(6): C1042–C1054. Published online 2021 Mar 31. doi: 10.1152/ajpcell.00597.2020

PMCID:: PMC8285635

Abstract Article

Select item 824325215.

DCLK1, a Putative Stem Cell Marker in Human Cholangiocarcinoma

Nevi Lorenzo, Di Matteo Sabina, Carpino Guido, Zizzari Ilaria Grazia, Safarikia Samira, Ambrosino Valeria, Costantini Daniele, Overi Diletta, Giancotti Antonella, Monti Marco, Bosco Daniela, De Peppo Valerio, Oddi Andrea, De Rose Agostino Maria, Melandro Fabio, Bragazzi Maria Consiglia, Faccioli Jessica, Massironi Sara, Grazi Gian Luca, Panici Pierluigi Benedetti, Berloco Paquale Bartomeo, Giuliante Felice, Cardinale Vincenzo, Invernizzi Pietro, Caretti Giuseppina, Gaudio Eugenio, Alvaro Domenico

Hepatology. 2021 Jan; 73(1): 144–159. Published online 2021 Feb 6. doi: 10.1002/hep.31571

Correction in:: Hepatology. 2022 Mar; 75(3): 773.

PMCID:: PMC8243252

Abstract Article PDF–1.7M

Select item 820141716.

DCLK1 Is Detectable in Plasma of Patients with Barrett’s Esophagus and Esophageal Adenocarcinoma

Joshua Whorton, Sripathi M. Sureban, Randal May, Dongfeng Qu, Stan A. Lightfoot, Mohammad Madhoun, Milton Johnson, William M. Tierney, John T. Maple, Kenneth J. Vega, Courtney W. Houchen

Dig Dis Sci. Author manuscript; available in PMC 2021 Jun 14.

Published in final edited form as: Dig Dis Sci. 2015 Feb; 60(2): 509–513. Published online 2014 Oct 5. doi: 10.1007/s10620-014-3347-4

PMCID:: PMC8201417

Abstract Article PDF–1005K

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 805304218.

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

Yan Liu, Fleur M. Ferguson, Lianbo Li, Miljan Kuljanin, Caitlin E. Mills, Kartik Subramanian, Wayne Harshbarger, Sudershan Gondi, Jinhua Wang, Peter K. Sorger, Joseph D. Mancias, Nathanael S. Gray, Kenneth D. Westover

Cell Chem Biol. Author manuscript; available in PMC 2021 Apr 17.

Published in final edited form as: Cell Chem Biol. 2020 Oct 15; 27(10): 1229–1240.e4. Published online 2020 Aug 4. doi: 10.1016/j.chembiol.2020.07.011

PMCID:: PMC8053042

Abstract Article PDF–1.9M

Select item 794841219.

The X-linked intellectual disability gene product and E3 ubiquitin ligase KLHL15 degrades doublecortin proteins to constrain neuronal dendritogenesis

Jianing Song, Ronald A. Merrill, Andrew Y. Usachev, Stefan Strack

J Biol Chem. 2021 Jan-Jun; 296: 100082. Published online 2020 Nov 21. doi: 10.1074/jbc.RA120.016210

PMCID:: PMC7948412

Abstract Article PDF–3.8M

Select item 788390120.

DCLK1-isoform2 alternative splice variant promotes pancreatic tumor immunosuppressive M2-macrophage polarization

Parthasarathy Chandrakesan, Janani Panneerselvam, Randal May, Nathaniel Weygant, Dongfeng Qu, William Berry, Kamille Pitts, Ben Z. Stanger, Chinthalapally V. Rao, Michael S. Bronze, Courtney W. Houchen

Mol Cancer Ther. Author manuscript; available in PMC 2021 Feb 15.

Published in final edited form as: Mol Cancer Ther. 2020 Jul; 19(7): 1539–1549. Published online 2020 May 5. doi: 10.1158/1535-7163.MCT-19-0776

PMCID:: PMC7883901

Abstract Article PDF–2.6M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 84

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity