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Select item 111831371.

NCF4 attenuates colorectal cancer progression by modulating inflammasome activation and immune surveillance

Longjun Li, Rudi Mao, Shenli Yuan, Qingqing Xie, Jinyu Meng, Yu Gu, Siyu Tan, Xiaoqing Xu, Chengjiang Gao, Hongbin Liu, Chunhong Ma, Si Ming Man, Xiangbo Meng, Tao Xu, Xiaopeng Qi

Nat Commun. 2024; 15: 5170. Published online 2024 Jun 17. doi: 10.1038/s41467-024-49549-7

PMCID:: PMC11183137

Abstract Article PDF–7.1M

Select item 85455302.

NCF1/2/4 Are Prognostic Biomarkers Related to the Immune Infiltration of Kidney Renal Clear Cell Carcinoma

Yifei Chen, Fei He, Ruhua Wang, Menglin Yao, Yarui Li, Dan Guo, Shuixiang He

Biomed Res Int. 2021; 2021: 5954036. Published online 2021 Oct 18. doi: 10.1155/2021/5954036

PMCID:: PMC8545530

Abstract Article PDF–7.3M

Select item 75964573.

Association of NCF2, NCF4, and CYBA Gene Polymorphisms with Rheumatoid Arthritis in a Chinese Population

Tian-Ping Zhang, Rui Li, Qian Huang, Han-Feng Pan, Dong-Qing Ye, Xiao-Mei Li

J Immunol Res. 2020; 2020: 8528976. Published online 2020 Oct 20. doi: 10.1155/2020/8528976

PMCID:: PMC7596457

Abstract Article PDF–398K

Select item 67197184.

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Michael S. Haney, Christopher J. Bohlen, David W Morgens, James A. Ousey, Amira A. Barkal, C. Kimberly Tsui, Braeden Ego, Roni Levin, Roarke Kamber, Hannah Collins, Andrew Tucker, Amy Li, Daan Vorselen, Lorenzo Labitigan, Emily Crane, Evan Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, William J. Greenleaf, Billy Li, Michael P. Snyder, Irving L. Weissman, Julie A. Theriot, Sean R. Collins, Ben A. Barres, Michael C. Bassik

Nat Genet. Author manuscript; available in PMC 2019 Sep 3.

Published in final edited form as: Nat Genet. 2018 Dec; 50(12): 1716–1727. Published online 2018 Nov 5. doi: 10.1038/s41588-018-0254-1

PMCID:: PMC6719718

Abstract Article PDF–1.3M

Select item 61185905.

Inherited p40^phox deficiency differs from classic chronic granulomatous disease

Annemarie van de Geer, Alejandro Nieto-Patlán, Douglas B. Kuhns, Anton T.J. Tool, Andrés A. Arias, Matthieu Bouaziz, Martin de Boer, José Luis Franco, Roel P. Gazendam, John L. van Hamme, Michel van Houdt, Karin van Leeuwen, Paul J.H. Verkuijlen, Timo K. van den Berg, Juan F. Alzate, Carlos A. Arango-Franco, Vritika Batura, Andrea R. Bernasconi, Barbara Boardman, Claire Booth, Siobhan O. Burns, Felipe Cabarcas, Nadine Cerf Bensussan, Fabienne Charbit-Henrion, Anniek Corveleyn, Caroline Deswarte, María Esnaola Azcoiti, Dirk Foell, John I. Gallin, Carlos Garcés, Margarida Guedes, Claas H. Hinze, Steven M. Holland, Stephen M. Hughes, Patricio Ibañez, Harry L. Malech, Isabelle Meyts, Marcela Moncada-Velez, Kunihiko Moriya, Esmeralda Neves, Matias Oleastro, Laura Perez, Vimel Rattina, Carmen Oleaga-Quintas, Neil Warner, Aleixo M. Muise, Jeanet Serafín López, Eunice Trindade, Julia Vasconcelos, Séverine Vermeire, Helmut Wittkowski, Austen Worth, Laurent Abel, Mary C. Dinauer, Peter D. Arkwright, Dirk Roos, Jean-Laurent Casanova, Taco W. Kuijpers, Jacinta Bustamante

J Clin Invest. 2018 Aug 31; 128(9): 3957–3975. Published online 2018 Aug 6. doi: 10.1172/JCI97116

PMCID:: PMC6118590

Abstract Article PDF–7.6M

Select item 58180556.

Tks adaptor proteins at a glance

Priyanka Saini, Sara A. Courtneidge

J Cell Sci. 2018 Jan 1; 131(1): jcs203661. doi: 10.1242/jcs.203661

PMCID:: PMC5818055

Abstract Article

Select item 56375467.

CYBA encoding p22^phox, the cytochrome b₅₅₈ alpha polypeptide: gene structure, expression, role and physiopathology

Marie José Stasia

Gene. Author manuscript; available in PMC 2017 Oct 12.

Published in final edited form as: Gene. 2016 Jul 15; 586(1): 27–35. Published online 2016 Apr 2. doi: 10.1016/j.gene.2016.03.050

PMCID:: PMC5637546

Abstract Article PDF–632K

Select item 45681228.

Hematologically Important Mutations: The Autosomal Recessive Forms of Chronic Granulomatous Disease (Second Update)

Dirk Roos, Douglas B. Kuhns, Anne Maddalena, Jacinta Bustamante, Caroline Kannengiesser, Martin de Boer, Karin van Leeuwen, M. Yavuz Köker, Baruch Wolach, Joachim Roesler, Harry L. Malech, Steven M. Holland, John I. Gallin, Marie-José Stasia

Blood Cells Mol Dis. Author manuscript; available in PMC 2015 Sep 13.

Published in final edited form as: Blood Cells Mol Dis. 2010 Apr 15; 44(4): 291–299. Published online 2010 Feb 18. doi: 10.1016/j.bcmd.2010.01.009

PMCID:: PMC4568122

Article PDF–731K

Select item 41149289.

Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: Outsourcing a key task

Edgar Pick

Small GTPases. 2014; 5: e27952. Published online 2014 Mar 5. doi: 10.4161/sgtp.27952

PMCID:: PMC4114928

Abstract Article PDF–5.8M

Select item 394735110.

Germline variation in NCF4, an innate immunity gene, is associated with an increased risk of colorectal cancer

Bríd M. Ryan, Krista A. Zanetti, Ana I. Robles, Aaron J. Schetter, Julie Goodman, Richard B. Hayes, Wen-Yi Huang, Marc J. Gunter, Meredith Yeager, Laurie Burdette, Sonja I. Berndt, Curtis C. Harris

Int J Cancer. Author manuscript; available in PMC 2015 Mar 15.

Published in final edited form as: Int J Cancer. 2014 Mar 15; 134(6): 1399–1407. Published online 2013 Nov 14. doi: 10.1002/ijc.28457

PMCID:: PMC3947351

Abstract Article PDF–341K

Select item 389378311.

Identification of proteins that interact with alpha A-crystallin using a human proteome microarray

Qi Fan, Lv-Zhen Huang, Xiang-Jia Zhu, Ke-Ke Zhang, Hong-Fei Ye, Yi Luo, Xing-Huai Sun, Peng Zhou, Yi Lu

Mol Vis. 2014; 20: 117–124. Published online 2014 Jan 14.

PMCID:: PMC3893783

Abstract Article PDF–1024K

Select item 363953212.

Association of Anthracycline-Related Cardiac Histological Lesions With NADPH Oxidase Functional Polymorphisms

Almudena Cascales, Francisco Pastor-Quirante, Beatriz Sánchez-Vega, Ginés Luengo-Gil, Javier Corral, Guzmán Ortuño-Pacheco, Vicente Vicente, Francisco Ayala de la Peña

Oncologist. 2013 Apr; 18(4): 446–453. Published online 2013 Apr 10. doi: 10.1634/theoncologist.2012-0239

PMCID:: PMC3639532

Abstract Article PDF–618K

Select item 346639913.

NADPH oxidase modulates MHC class II antigen presentation by B cells

Victoria L. Crotzer, Juan D. Matute, Andrés A. Arias, Heng Zhao, Lawrence A. Quilliam, Mary C. Dinauer, Janice S. Blum

J Immunol. Author manuscript; available in PMC 2013 Oct 15.

Published in final edited form as: J Immunol. 2012 Oct 15; 189(8): 3800–3804. Published online 2012 Sep 14. doi: 10.4049/jimmunol.1103080

PMCID:: PMC3466399

Abstract Article PDF–551K

Select item 327237514.

META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IDENTIFIES THREE NEW RISK LOCI FOR ATOPIC DERMATITIS

Lavinia Paternoster, Marie Standl, Chih-Mei Chen, Adaikalavan Ramasamy, Klaus Bønnelykke, Liesbeth Duijts, Manuel A Ferreira, Alexessander Couto Alves, Jacob P Thyssen, Eva Albrecht, Hansjörg Baurecht, Bjarke Feenstra, Patrick MA Sleiman, Pirro Hysi, Nicole M Warrington, Ivan Curjuric, Ronny Myhre, John A Curtin, Maria M Groen-Blokhuis, Marjan Kerkhof, Annika Sääf, Andre Franke, David Ellinghaus, Regina Fölster-Holst, Emmanouil Dermitzakis, Stephen B Montgomery, Holger Prokisch, Katharina Heim, Anna-Liisa Hartikainen, Anneli Pouta, Juha Pekkanen, Alexandra IF Blakemore, Jessica L Buxton, Marika Kaakinen, David L Duffy, Pamela A Madden, Andrew C Heath, Grant W Montgomery, Philip J Thompson, Melanie C Matheson, Peter Le Souëf, AAGC collaborators, Beate St Pourcain, George Davey Smith, John Henderson, John P Kemp, Nicholas J Timpson, Panos Deloukas, Susan M Ring, H-Erich Wichmann, Martina Müller-Nurasyid, Natalija Novak, Norman Klopp, Elke Rodríguez, Wendy McArdle, Allan Linneberg, Torkil Menné, Ellen A Nohr, Albert Hofman, André G Uitterlinden, Cornélia M van Duijn, Fernando Rivadeneira, Johan C de Jongste, Ralf JP van der Valk, Matthias Wjst, Rain Jogi, Frank Geller, Heather A Boyd, Jeffrey C Murray, Cecilia Kim, Frank Mentch, Michael March, Massimo Mangino, Tim D Spector, Veronique Bataille, Craig E Pennell, Patrick G Holt, Peter Sly, Carla MT Tiesler, Elisabeth Thiering, Thomas Illig, Medea Imboden, Wenche Nystad, Angela Simpson, Jouke-Jan Hottenga, Dirkje Postma, Gerard H Koppelman, Henriette A Smit, Cilla Söderhäll, Bo Chawes, Eskil Kreiner-Møller, Hans Bisgaard, Erik Melén, Dorret I Boomsma, Adnan Custovic, Bo Jacobsson, Nicole M Probst-Hensch, Lyle J Palmer, Daniel Glass, Hakon Hakonarson, Mads Melbye, Deborah L Jarvis, Vincent WV Jaddoe, Christian Gieger, The GOYA consortium, David P Strachan, Nicholas G Martin, Marjo-Riitta Jarvelin, Joachim Heinrich, David M Evans, Stephan Weidinger

Nat Genet. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Nat Genet. 2011 Dec 25; 44(2): 187–192. Published online 2011 Dec 25. doi: 10.1038/ng.1017

PMCID:: PMC3272375

Abstract Article PDF–1.2M

Select item 322046215.

Cooperation of p40^phox with p47^phox for Nox2-based NADPH Oxidase Activation during Fcγ Receptor (FcγR)-mediated Phagocytosis: MECHANISM FOR ACQUISITION OF p40^phox PHOSPHATIDYLINOSITOL 3-PHOSPHATE (PI(3)P) BINDING

Takehiko Ueyama, Junya Nakakita, Takashi Nakamura, Takeshi Kobayashi, Toshihiro Kobayashi, Jeonghyun Son, Megumi Sakuma, Hirofumi Sakaguchi, Thomas L. Leto, Naoaki Saito

J Biol Chem. 2011 Nov 25; 286(47): 40693–40705. Published online 2011 Sep 28. doi: 10.1074/jbc.M111.237289

PMCID:: PMC3220462

Abstract Article PDF–2.5M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316916717.

Risk of Meningioma and Common Variation in Genes related to Innate Immunity

Preetha Rajaraman, Alina V. Brenner, Gila Neta, Ruth Pfeiffer, Sophia S. Wang, Meredith Yeager, Gilles Thomas, Howard A. Fine, Martha S. Linet, Nathaniel Rothman, Stephen J. Chanock, Peter D. Inskip

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Sep 7.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 May; 19(5): 1356–1361. Published online 2010 Apr 20. doi: 10.1158/1055-9965.EPI-09-1151

PMCID:: PMC3169167

Abstract Article PDF–61K

Select item 296777018.

Polymorphisms in innate immunity genes and risk of childhood leukemia

Sohee Han, Qing Lan, Ae Kyung Park, Kyoung-Mu Lee, Sue K. Park, Hyo Seop Ahn, Hee Young Shin, Hyoung Jin Kang, Hong Hoe Koo, Jong Jin Seo, Ji Eun Choi, Yoon-Ok Ahn, Stephen J. Chanock, Ho Kim, Nathaniel Rothman, Daehee Kang

Hum Immunol. Author manuscript; available in PMC 2010 Nov 2.

Published in final edited form as: Hum Immunol. 2010 Jul; 71(7): 727–730. Published online 2010 May 16. doi: 10.1016/j.humimm.2010.04.004

PMCID:: PMC2967770

Abstract Article PDF–306K

Select item 296535519.

Genetic polymorphisms in nitric oxide synthase genes modify the relationship between vegetable and fruit intake and risk of non-Hodgkin lymphoma

Xuesong Han, Tongzhang Zheng, Qing Lan, Yaqun Zhang, Briseis A. Kilfoy, Qin Qin, Nathaniel Rothman, Shelia H. Zahm, Theodore R. Holford, Brian Leaderer, Yawei Zhang

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2010 Oct 28.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 May; 18(5): 1429–1438. doi: 10.1158/1055-9965.EPI-09-0001

PMCID:: PMC2965355

Abstract Article PDF–67K

Select item 294516820.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

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