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Items: 15

1.
Correlation of CpG Island Methylation of the Cytochrome P450 2E1/2D6 Genes with Liver Injury Induced by Anti-Tuberculosis Drugs: A Nested Case-Control Study
Jinling Zhang, Xuebin Zhu, Yuhong Li, Lingyan Zhu, Shiming Li, Guoying Zheng, Qi Ren, Yonghong Xiao, Fumin Feng
Int J Environ Res Public Health. 2016 Aug; 13(8): 776. Published online 2016 Aug 1. doi: 10.3390/ijerph13080776
PMCID:
PMC4997462
AbstractArticlePDF–751K
2.
Effect of Traumatic Brain Injury, Erythropoietin, and Anakinra on Hepatic Metabolizing Enzymes and Transporters in an Experimental Rat Model
Gail D. Anderson, Todd C. Peterson, Cole Vonder Haar, Fred M. Farin, Theo K. Bammler, James W. MacDonald, Eric D. Kantor, Michael R. Hoane
AAPS J. 2015 Sep; 17(5): 1255–1267. Published online 2015 Jun 12. doi: 10.1208/s12248-015-9792-y
PMCID:
PMC4540723
AbstractArticlePDF–643K
3.
First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo
Kaidi Zhou, Jibran Y. Khokhar, Bin Zhao, Rachel F. Tyndale
Biochem Pharmacol. Author manuscript; available in PMC 2014 Jun 15.
Published in final edited form as: Biochem Pharmacol. 2013 Jun 15; 85(12): 1848–1855. Published online 2013 Apr 23. doi: 10.1016/j.bcp.2013.04.014
PMCID:
PMC3687523
AbstractArticlePDF–890K
4.
Effects of Schizonepetin on Activity and mRNA Expression of Cytochrome P450 Enzymes in Rats
Beihua Bao, Ting Geng, Yudan Cao, Weifeng Yao, Li Zhang, Anwei Ding
Int J Mol Sci. 2012; 13(12): 17006–17018. Published online 2012 Dec 12. doi: 10.3390/ijms131217006
PMCID:
PMC3546736
AbstractArticlePDF–262K
5.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
6.
Anandamide Oxidation by Wild-Type and Polymorphically Expressed CYP2B6 and CYP2D6
Chitra Sridar, Natasha T. Snider, Paul F. Hollenberg
Drug Metab Dispos. 2011 May; 39(5): 782–788. doi: 10.1124/dmd.110.036707
PMCID:
PMC3082373
AbstractArticlePDF–937K
7.
No influence of the polymorphisms CYP2C19 and CYP2D6 on the efficacy of cyclophosphamide, thalidomide, and bortezomib in patients with Multiple Myeloma
Annette J Vangsted, Karen Søeby, Tobias W Klausen, Niels Abildgaard, Niels F Andersen, Peter Gimsing, Henrik Gregersen, Ulla Vogel, Thomas Werge, Henrik B Rasmussen
BMC Cancer. 2010; 10: 404. Published online 2010 Aug 4. doi: 10.1186/1471-2407-10-404
PMCID:
PMC2922196
AbstractArticlePDF–283K
8.
Human Liver Mitochondrial Cytochrome P450 2D6: Individual Variations and Implications in Drug Metabolism
Michelle L. Cook Sangar, Hindupur K. Anandatheerthavarada, Weigang Tang, Subbuswamy K. Prabu, Martha V. Martin, Miroslav Dostalek, F. Peter Guengerich, Narayan G. Avadhani
FEBS J. Author manuscript; available in PMC 2010 Jul 1.
Published in final edited form as: FEBS J. 2009 Jul; 276(13): 3440–3453. Published online 2009 May 11. doi: 10.1111/j.1742-4658.2009.07067.x
PMCID:
PMC2789264
AbstractArticlePDF–646K
9.
Hepatic Cytochrome P450 Enzyme Alterations in Humans with Progressive Stages of Nonalcoholic Fatty Liver Disease
Craig D. Fisher, Andrew J. Lickteig, Lisa M. Augustine, James Ranger-Moore, Jonathan P. Jackson, Stephen S. Ferguson, Nathan J. Cherrington
Drug Metab Dispos. 2009 Oct; 37(10): 2087–2094. doi: 10.1124/dmd.109.027466
PMCID:
PMC2769034
AbstractArticlePDF–3.3M
10.
CYP2D6-CYP2C9 Protein-Protein Interactions and Isoform-Selective Effects on Substrate Binding and Catalysis
Murali Subramanian, Michael Low, Charles W. Locuson, Timothy S. Tracy
Drug Metab Dispos. 2009 Aug; 37(8): 1682–1689. Published online 2009 May 15. doi: 10.1124/dmd.109.026500
PMCID:
PMC2712436
AbstractArticlePDF–216K
11.
Changes in Maternal liver Cyp2c and Cyp2d Expression and Activity During Rat Pregnancy
Leslie J. Dickmann, Suzanne Tay, Tauri D. Senn, Huixia Zhang, Anthony Visone, Jashvant D. Unadkat, Mary F. Hebert, Nina Isoherranen
Biochem Pharmacol. Author manuscript; available in PMC 2009 May 18.
Published in final edited form as: Biochem Pharmacol. 2008 Apr 15; 75(8): 1677–1687. Published online 2008 Feb 7. doi: 10.1016/j.bcp.2008.01.012
PMCID:
PMC2683271
AbstractArticlePDF–907K
12.
Radical Intermediates in the Catalytic Oxidation of Hydrocarbons by Bacterial and Human Cytochrome P450 Enzymes
Yongying Jiang, Xiang He, Paul R. Ortiz de Montellano
Biochemistry. Author manuscript; available in PMC 2008 Oct 10.
Published in final edited form as: Biochemistry. 2006 Jan 17; 45(2): 533–542. doi: 10.1021/bi051840z
PMCID:
PMC2566308
AbstractArticlePDF–579K
13.
Characterization of human cytochrome P450 enzymes catalyzing domperidone N-dealkylation and hydroxylation in vitro
Bryan A Ward, Alan Morocho, Abdullah Kandil, Raymond E Galinsky, David A Flockhart, Zeruesenay Desta
Br J Clin Pharmacol. 2004 Sep; 58(3): 277–287. doi: 10.1111/j.1365-2125.2004.02156.x
PMCID:
PMC1884565
AbstractArticlePDF–202K
14.
Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism.
A Gaedigk, M Blum, R Gaedigk, M Eichelbaum, U A Meyer
Am J Hum Genet. 1991 May; 48(5): 943–950.
PMCID:
PMC1683061
SummaryPage BrowsePDF–1.3M
15.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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