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Items: 1 to 20 of 83

1.
Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradation
Ning Li, Qianyin Zhou, Zhang Yi, Huan Zhang, Dai Zhou
Biol Res. 2023; 56: 4. Published online 2023 Jan 23. doi: 10.1186/s40659-023-00413-w
PMCID:
PMC9869568
AbstractArticlePDF–7.6M
2.
Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics
Francesca Ferrante, Benedetto Daniele Giaimo, Tobias Friedrich, Toshiya Sugino, Daniel Mertens, Sabrina Kugler, Bernd Martin Gahr, Steffen Just, Leiling Pan, Marek Bartkuhn, Michael Potente, Franz Oswald, Tilman Borggrefe
Cell Death Dis. 2022 Jul; 13(7): 600. Published online 2022 Jul 12. doi: 10.1038/s41419-022-05052-9
PMCID:
PMC9276811
AbstractArticlePDF–1.8M
3.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
4.
Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins
Thomas M. Leissing, Adam P. Hardy, Hokfung Chan, Yihua Wang, Anthony Tumber, Rasheduzzaman Chowdhury, Tianshu Feng, Mathew L. Coleman, Matthew E. Cockman, Holger B. Kramer, Georgina Berridge, Roman Fischer, Benedikt M. Kessler, Peter J. Ratcliffe, Xin Lu, Christopher J. Schofield
J Biol Chem. 2022 Jun; 298(6): 102020. Published online 2022 May 7. doi: 10.1016/j.jbc.2022.102020
PMCID:
PMC9189129
AbstractArticlePDF–2.5M
5.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
6.
TMEM161B‐AS1 suppresses proliferation, invasion and glycolysis by targeting miR‐23a‐3p/HIF1AN signal axis in oesophageal squamous cell carcinoma
Zuxuan Shi, Guanghui Li, Zhen Li, Junhao Liu, Yu Tang
J Cell Mol Med. 2021 Jul; 25(14): 6535–6549. Published online 2021 May 27. doi: 10.1111/jcmm.16652
Correction in:
J Cell Mol Med. 2023 Feb; 27(4): 591–592.
PMCID:
PMC8278070
AbstractArticlePDF–3.0M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1
Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi
J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162
PMCID:
PMC7948964
AbstractArticlePDF–2.7M
9.
miR-212 promotes renal interstitial fibrosis by inhibiting hypoxia-inducible factor 1-α inhibitor
Yun Zhang, Guo-Xin Zhang, Li-Shuang Che, Shu-Han Shi, Yue-Ting Li
Mol Med Rep. 2021 Mar; 23(3): 189. Published online 2021 Jan 6. doi: 10.3892/mmr.2021.11828
PMCID:
PMC7809912
AbstractArticlePDF–9.2M
10.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
11.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
12.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
13.
Oxygen-dependent asparagine hydroxylation of the ubiquitin-associated (UBA) domain in Cezanne regulates ubiquitin binding
Julia Mader, Jessica Huber, Florian Bonn, Volker Dötsch, Vladimir V. Rogov, Anja Bremm
J Biol Chem. 2020 Feb 21; 295(8): 2160–2174. Published online 2020 Jan 14. doi: 10.1074/jbc.RA119.010315
PMCID:
PMC7039550
AbstractArticlePDF–2.1M
14.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
15.
Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1
Christina Pickel, Julia Günter, Amalia Ruiz-Serrano, Patrick Spielmann, Jacqueline-Alba Fabrizio, Witold Wolski, Daniel J. Peet, Roland H. Wenger, Carsten C. Scholz
Redox Biol. 2019 Sep; 26: 101265. Published online 2019 Jul 2. doi: 10.1016/j.redox.2019.101265
PMCID:
PMC6624438
AbstractArticlePDF–2.0M
16.
Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment
Jianbo Feng, Yan Zhang, Xiaoling She, Yingnan Sun, Li Fan, Xing Ren, Haijuan Fu, Changhong Liu, Peiyao Li, Chunhua Zhao, Qiang Liu, Qing Liu, Guiyuan Li, Minghua Wu
Oncogene. 2019; 38(1): 103–119. Published online 2018 Aug 6. doi: 10.1038/s41388-018-0423-9
PMCID:
PMC6318269
AbstractArticlePDF–6.1M
17.
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively
Yihua Wang, Shan Zhong, Christopher J. Schofield, Peter J. Ratcliffe, Xin Lu
J Cell Sci. 2018 Nov 15; 131(22): jcs219782. Published online 2018 Nov 19. doi: 10.1242/jcs.219782
PMCID:
PMC6250434
AbstractArticle
18.
FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α
Jengmin Kang, Yang-Sook Chun, June Huh, Jong-Wan Park
Redox Biol. 2018 Oct; 19: 364–374. Published online 2018 Sep 7. doi: 10.1016/j.redox.2018.09.002
PMCID:
PMC6142190
AbstractArticlePDF–2.2M
19.
Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes
Gustavo Martínez-Noël, Katja Luck, Simone Kühnle, Alice Desbuleux, Patricia Szajner, Jeffrey T. Galligan, Diana Rodriguez, Leon Zheng, Kathleen Boyland, Flavian Leclere, Quan Zhong, David E. Hill, Marc Vidal, Peter M. Howley
J Mol Biol. Author manuscript; available in PMC 2019 Mar 30.
Published in final edited form as: J Mol Biol. 2018 Mar 30; 430(7): 1024–1050. Published online 2018 Feb 6. doi: 10.1016/j.jmb.2018.01.021
PMCID:
PMC5866790
AbstractArticlePDF–4.1M
20.
Factor inhibiting HIF1–A novel target of SUMOylation in the human placenta
Julien Sallais, Sruthi Alahari, Andrea Tagliaferro, Jayonta Bhattacharjee, Martin Post, Isabella Caniggia
Oncotarget. 2017 Dec 26; 8(69): 114002–114018. Published online 2017 Dec 7. doi: 10.18632/oncotarget.23113
PMCID:
PMC5768381
AbstractArticlePDF–3.3M

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