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Items: 1 to 20 of 48

1.
Methylation of ESCRT-III components regulates the timing of cytokinetic abscission
Aurélie Richard, Jérémy Berthelet, Delphine Judith, Tamara Advedissian, Javier Espadas, Guillaume Jannot, Angélique Amo, Damarys Loew, Berangere Lombard, Alexandre G. Casanova, Nicolas Reynoird, Aurélien Roux, Clarisse Berlioz-Torrent, Arnaud Echard, Jonathan B. Weitzman, Souhila Medjkane
Nat Commun. 2024; 15: 4023. Published online 2024 May 13. doi: 10.1038/s41467-024-47717-3
PMCID:
PMC11091153
AbstractArticlePDF–3.4M
2.
SMYD2 Promotes Hepatocellular Carcinoma Progression by Reprogramming Glutamine Metabolism via c-Myc/GLS1 Axis
Kangdi Xu, Jun Ding, Lingfeng Zhou, Dazhi Li, Jia Luo, Wenchao Wang, Mingge Shang, Bingyi Lin, Lin Zhou, Shusen Zheng
Cells. 2023 Jan; 12(1): 25. Published online 2022 Dec 21. doi: 10.3390/cells12010025
PMCID:
PMC9818721
AbstractArticlePDF–4.5M
3.
Mechanistic and functional extrapolation of SET and MYND domain-containing protein 2 to pancreatic cancer
Eid Alshammari, Ying-Xue Zhang, Zhe Yang
World J Gastroenterol. 2022 Aug 7; 28(29): 3753–3766. Published online 2022 Aug 7. doi: 10.3748/wjg.v28.i29.3753
PMCID:
PMC9367238
AbstractArticlePDF–759K
4.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
5.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
6.
SMYD2 Inhibition Downregulates TMPRSS2 and Decreases SARS-CoV-2 Infection in Human Intestinal and Airway Epithelial Cells
Yu-Qiang Yu, Alexandra Herrmann, Veronika Thonn, Arne Cordsmeier, Markus F. Neurath, Armin Ensser, Christoph Becker
Cells. 2022 Apr; 11(8): 1262. Published online 2022 Apr 8. doi: 10.3390/cells11081262
PMCID:
PMC9033063
AbstractArticlePDF–4.0M
7.
SMYD2‐mediated TRAF2 methylation promotes the NF‐κB signaling pathways in inflammatory diseases
Weijun Wu, Jinghuan Wang, Chenxi Xiao, Zhenghua Su, Haibi Su, Wen Zhong, Jianchun Mao, Xinhua Liu, Yi Zhun Zhu
Clin Transl Med. 2021 Nov; 11(11): e591. Published online 2021 Nov 4. doi: 10.1002/ctm2.591
PMCID:
PMC8567046
AbstractArticlePDF–9.8M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
SMYD2 promotes tumorigenesis and metastasis of lung adenocarcinoma through RPS7
Lei Wu, Fan Kou, Zhenyu Ji, Baihui Li, Bailu Zhang, Yan Guo, Lili Yang
Cell Death Dis. 2021 May; 12(5): 439. Published online 2021 May 2. doi: 10.1038/s41419-021-03720-w
PMCID:
PMC8089105
AbstractArticlePDF–7.7M
10.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
11.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
12.
AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair
Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen
Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794
PMCID:
PMC7050103
AbstractArticlePDF–1.8M
13.
Analysis of the Substrate Specificity of the SMYD2 Protein Lysine Methyltransferase and Discovery of Novel Non‐Histone Substrates
Dr. Sara Weirich, Dr. Maren Kirstin Schuhmacher, Dr. Srikanth Kudithipudi, Dr. Cristiana Lungu, Dr. Andrew D. Ferguson, Prof. Dr. Albert Jeltsch
Chembiochem. 2020 Jan 15; 21(1-2): 256–264. Published online 2019 Oct 29. doi: 10.1002/cbic.201900582
PMCID:
PMC7003753
AbstractArticlePDF–1.1M
14.
Histone methyltransferase SMYD2: ubiquitous regulator of disease
Xin Yi, Xue-Jun Jiang, Ze-Min Fang
Clin Epigenetics. 2019; 11: 112. Published online 2019 Aug 1. doi: 10.1186/s13148-019-0711-4
PMCID:
PMC6670139
AbstractArticlePDF–1.3M
15.
A motif in HSP90 and P23 that links molecular chaperones to efficient estrogen receptor α methylation by the lysine methyltransferase SMYD2
Wolfgang M. J. Obermann
J Biol Chem. 2018 Oct 19; 293(42): 16479–16487. Published online 2018 Sep 6. doi: 10.1074/jbc.RA118.003578
PMCID:
PMC6200951
AbstractArticlePDF–2.0M
16.
Overexpression of SET and MYND Domain-Containing Protein 2 (SMYD2) Is Associated with Tumor Progression and Poor Prognosis in Patients with Papillary Thyroid Carcinoma
Wenchao Xu, Fulian Chen, Xiao Fei, Xiaoqing Yang, Xiaofei Lu
Med Sci Monit. 2018; 24: 7357–7365. Published online 2018 Oct 15. doi: 10.12659/MSM.910168
PMCID:
PMC6198713
AbstractArticlePDF–1.1M
17.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
18.
Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation
Michael J. Thomenius, Jennifer Totman, Darren Harvey, Lorna H. Mitchell, Thomas V. Riera, Kat Cosmopoulos, Alexandra R. Grassian, Christine Klaus, Megan Foley, Elizabeth A. Admirand, Haris Jahic, Christina Majer, Tim Wigle, Suzanne L. Jacques, Jodi Gureasko, Dorothy Brach, Trupti Lingaraj, Kip West, Sherri Smith, Nathalie Rioux, Nigel J. Waters, Cuyue Tang, Alejandra Raimondi, Michael Munchhof, James E. Mills, Scott Ribich, Margaret Porter Scott, Kevin W. Kuntz, William P. Janzen, Mikel Moyer, Jesse J. Smith, Richard Chesworth, Robert A. Copeland, P. Ann Boriack-Sjodin
PLoS One. 2018; 13(6): e0197372. Published online 2018 Jun 1. doi: 10.1371/journal.pone.0197372
PMCID:
PMC5983452
AbstractArticlePDF–5.7M
19.
SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells
Bradley J. Toghill, Athanasios Saratzis, Peter J. Freeman, Nicolas Sylvius, UKAGS collaborators, Matthew J. Bown
Clin Epigenetics. 2018; 10: 29. Published online 2018 Mar 2. doi: 10.1186/s13148-018-0460-9
PMCID:
PMC5833080
AbstractArticlePDF–1.3M
20.
Lysine methyltransferase SMYD2 promotes triple negative breast cancer progression
Linda Xiaoyan Li, Julie Xia Zhou, James P. Calvet, Andrew K. Godwin, Roy A. Jensen, Xiaogang Li
Cell Death Dis. 2018 Mar; 9(3): 326. Published online 2018 Feb 27. doi: 10.1038/s41419-018-0347-x
PMCID:
PMC5832424
AbstractArticlePDF–3.1M

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