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Select item 98925211.

LncRNA TINCR impairs the efficacy of immunotherapy against breast cancer by recruiting DNMT1 and downregulating MiR-199a-5p via the STAT1–TINCR-USP20-PD-L1 axis

Qin Wang, Guozheng Li, Xin Ma, Lei Liu, Jiena Liu, Yanling Yin, Hui Li, Yihai Chen, Xin Zhang, Lei Zhang, Liyang Sun, Jing Ai, Shouping Xu

Cell Death Dis. 2023 Feb; 14(2): 76. Published online 2023 Feb 1. doi: 10.1038/s41419-023-05609-2

PMCID:: PMC9892521

Abstract Article PDF–5.4M

Select item 96689042.

The long noncoding RNA TINCR promotes self-renewal of human liver cancer stem cells through autophagy activation

Jing Shi, Cao Guo, Yang Li, Junli Ma

Cell Death Dis. 2022 Nov; 13(11): 961. Published online 2022 Nov 16. doi: 10.1038/s41419-022-05424-1

PMCID:: PMC9668904

Abstract Article PDF–4.5M

Select item 96523153.

pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation

Olga Boix, Marion Martinez, Santiago Vidal, Marta Giménez-Alejandre, Lluís Palenzuela, Laura Lorenzo-Sanz, Laura Quevedo, Olivier Moscoso, Jorge Ruiz-Orera, Pilar Ximénez-Embún, Nikaoly Ciriaco, Paolo Nuciforo, Camille Stephan-Otto Attolini, M. Mar Albà, Javier Muñoz, Tian V. Tian, Ignacio Varela, Ana Vivancos, Santiago Ramón y Cajal, Purificación Muñoz, Carmen Rivas, María Abad

Nat Commun. 2022; 13: 6840. Published online 2022 Nov 11. doi: 10.1038/s41467-022-34529-6

PMCID:: PMC9652315

Abstract Article PDF–8.6M

Select item 89739664.

Long non-coding RNA terminal differentiation-induced non-coding RNA regulates cisplatin resistance of choroidal melanoma by positively modulating extracellular signal-regulated kinase 2 via sponging microRNA-19b-3p

Wei Li, Aiqin Nie, Longyu Jin, Yubo Cui, Ning Xie, Gaohua Liang

Bioengineered. 2022; 13(2): 3422–3433. Published online 2022 Jan 22. doi: 10.1080/21655979.2021.2014618

PMCID:: PMC8973966

Abstract Article PDF–2.4M

Select item 88551655.

Expression of SOX2OT, DANCR and TINCR long non-coding RNAs in papillary thyroid cancer and its effects on clinicopathological features

Fadime Mutlu Icduygu, Egemen Akgun, Demet Sengul, Asuman Ozgoz, Ebru Alp

Mol Med Rep. 2022 Apr; 25(4): 120. Published online 2022 Feb 10. doi: 10.3892/mmr.2022.12636

PMCID:: PMC8855165

Abstract Article PDF–661K

Select item 88067926.

Long non-coding RNA TINCR promotes hepatocellular carcinoma proliferation and invasion via STAT3 signaling by direct interacting with T-cell protein tyrosine phosphatase (TCPTP)

Chengwu Tang, Wenming Feng, Ying Bao, Huimin Du

Bioengineered. 2021; 12(1): 2119–2131. Published online 2021 May 30. doi: 10.1080/21655979.2021.1930336

PMCID:: PMC8806792

Abstract Article PDF–2.4M

Select item 83416627.

A ubiquitin-like protein encoded by the “noncoding” RNA TINCR promotes keratinocyte proliferation and wound healing

Akihiro Nita, Akinobu Matsumoto, Ronghao Tang, Chisa Shiraishi, Kazuya Ichihara, Daisuke Saito, Mikita Suyama, Tomoharu Yasuda, Gaku Tsuji, Masutaka Furue, Bumpei Katayama, Toshiyuki Ozawa, Teruasa Murata, Teruki Dainichi, Kenji Kabashima, Atsushi Hatano, Masaki Matsumoto, Keiichi I. Nakayama

PLoS Genet. 2021 Aug; 17(8): e1009686. Published online 2021 Aug 5. doi: 10.1371/journal.pgen.1009686

PMCID:: PMC8341662

Abstract Article PDF–4.2M

Select item 80207678.

Noncanonical immune response to the inhibition of DNA methylation by Staufen1 via stabilization of endogenous retrovirus RNAs

Yongsuk Ku, Joo-Hwan Park, Ryeongeun Cho, Yongki Lee, Hyoung-Min Park, MinA Kim, Kyunghoon Hur, Soo Young Byun, Jun Liu, Young-suk Lee, David Shum, Dong-Yeop Shin, Youngil Koh, Je-Yoel Cho, Sung-Soo Yoon, Junshik Hong, Yoosik Kim

Proc Natl Acad Sci U S A. 2021 Mar 30; 118(13): e2016289118. Published online 2021 Mar 24. doi: 10.1073/pnas.2016289118

PMCID:: PMC8020767

Abstract Article PDF–2.8M

Select item 78514389.

Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state

Norihito Omote, Koji Sakamoto, Qin Li, Jonas C. Schupp, Taylor Adams, Farida Ahangari, Maurizio Chioccioli, Giuseppe DeIuliis, Naozumi Hashimoto, Yoshinori Hasegawa, Naftali Kaminski

Physiol Rep. 2021 Feb; 9(3): e14727. Published online 2021 Feb 1. doi: 10.14814/phy2.14727

PMCID:: PMC7851438

Abstract Article PDF–2.4M

Select item 780945010.

LncRNA TINCR favors tumorigenesis via STAT3–TINCR–EGFR-feedback loop by recruiting DNMT1 and acting as a competing endogenous RNA in human breast cancer

Qin Wang, Jiena Liu, Zilong You, Yanling Yin, Lei Liu, Yujuan Kang, Siwei Li, Shipeng Ning, Hui Li, Yajie Gong, Shouping Xu, Da Pang

Cell Death Dis. 2021 Jan; 12(1): 83. Published online 2021 Jan 14. doi: 10.1038/s41419-020-03188-0

PMCID:: PMC7809450

Abstract Article PDF–4.8M

Select item 778599911.

Serum lncRNA TINCR Serve as a Novel Biomarker for Predicting the Prognosis in Triple-Negative Breast Cancer

Xiaojie Wang, Shuang Li, Huiyu Xiao, Xiaoqin Deng

Technol Cancer Res Treat. 2020; 19: 1533033820965574. Published online 2020 Oct 21. doi: 10.1177/1533033820965574

PMCID:: PMC7785999

Abstract Article PDF–735K

Select item 753351112.

lncRNA TINCR facilities bladder cancer progression via regulating miR-7 and mTOR

Guoying Xu, Honglan Yang, Meichun Liu, Jintao Niu, Weidong Chen, Xiaojing Tan, Li Sun

Mol Med Rep. 2020 Nov; 22(5): 4243–4253. Published online 2020 Sep 22. doi: 10.3892/mmr.2020.11530

PMCID:: PMC7533511

Abstract Article PDF–1.4M

Select item 738882413.

miR-589-3p sponged by the lncRNA TINCR inhibits the proliferation, migration and invasion and promotes the apoptosis of breast cancer cells by suppressing the Akt pathway via IGF1R

Fangdong Guo, Xiaoyu Zhu, Qingquan Zhao, Qirong Huang

Int J Mol Med. 2020 Sep; 46(3): 989–1002. Published online 2020 Jul 2. doi: 10.3892/ijmm.2020.4666

PMCID:: PMC7388824

Abstract Article PDF–1.6M

Select item 718723114.

TINCR is not a non‐coding RNA but encodes a protein component of cornified epidermal keratinocytes

Leopold Eckhart, Julia Lachner, Erwin Tschachler, Robert H. Rice

Exp Dermatol. 2020 Apr; 29(4): 376–379. Published online 2020 Feb 18. doi: 10.1111/exd.14083

PMCID:: PMC7187231

Abstract Article PDF–540K

Select item 673425915.

LncRNA PLAC 2 downregulated miR-21 in non-small cell lung cancer and predicted survival

Huan Xia, Ming Xiu, Jinying Gao, Hongyu Jing

BMC Pulm Med. 2019; 19: 172. Published online 2019 Sep 10. doi: 10.1186/s12890-019-0931-6

PMCID:: PMC6734259

Abstract Article PDF–790K

Select item 664230416.

Association between the rs2288947 polymorphism of the lncRNA TINCR gene and the risk of recurrent miscarriage in a Southern Chinese population

Wendong Huang, Huazhong Zhou, Lei Pi, Yufen Xu, LanYan Fu, Yanfang Yang, Di Che, Xiaoqiong Gu

J Clin Lab Anal. 2019 Jul; 33(6): e22919. Published online 2019 May 23. doi: 10.1002/jcla.22919

PMCID:: PMC6642304

Abstract Article PDF–344K

Select item 641135217.

lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β-catenin pathway in oral squamous cell carcinoma

Fubo Chen, Shengcai Qi, Xu Zhang, Jinjin Wu, Xi yang, Raorao Wang

Int J Oncol. 2019 Apr; 54(4): 1183–1194. Published online 2019 Feb 1. doi: 10.3892/ijo.2019.4707

PMCID:: PMC6411352

Abstract Article PDF–1.6M

Select item 588388018.

Up-regulation of ceRNA TINCR by SP1 contributes to tumorigenesis in breast cancer

Yun Liu, Yaying Du, Xiaopeng Hu, Lu Zhao, Wenfei Xia

BMC Cancer. 2018; 18: 367. Published online 2018 Apr 3. doi: 10.1186/s12885-018-4255-3

PMCID:: PMC5883880

Abstract Article PDF–2.7M

Select item 567858119.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9