PMC Links for GEO Profiles (Select 48691607) - PMC

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100237684.

Novel germline variants of CDKN1B and CDKN2C identified during screening for familial primary hyperparathyroidism

I. Mazarico-Altisent, I. Capel, N. Baena, M. R. Bella-Cueto, S. Barcons, X. Guirao, L. Albert, A. Cano, R. Pareja, A. Caixàs, M. Rigla

J Endocrinol Invest. 2023; 46(4): 829–840. Published online 2022 Nov 5. doi: 10.1007/s40618-022-01948-7

PMCID:: PMC10023768

Abstract Article PDF–1.0M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 86714986.

The distinct effects of P18 overexpression on different stages of hematopoiesis involve TGF-β and NF-κB signaling

Danying Yi, Lijiao Zhu, Yuanling Liu, Jiahui Zeng, Jing Chang, Wencui Sun, Jiawen Teng, Yonggang Zhang, Yong Dong, Xu Pan, Yijin Chen, Ya Zhou, Mowen Lai, Qiongxiu Zhou, Jiaxin Liu, Bo Chen, Feng Ma

Sci Rep. 2021; 11: 24014. Published online 2021 Dec 14. doi: 10.1038/s41598-021-03263-2

PMCID:: PMC8671498

Abstract Article PDF–1.8M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79256798.

Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replication

Yueshuo Li, Feng Shi, Jianmin Hu, Longlong Xie, Lin Zhao, Min Tang, Xiangjian Luo, Mao Ye, Hui Zheng, Min Zhou, Na Liu, Ann M. Bode, Jia Fan, Jian Zhou, Qiang Gao, Shuangjian Qiu, Weizhong Wu, Xin Zhang, Weihua Liao, Ya Cao

NPJ Precis Oncol. 2021; 5: 14. Published online 2021 Mar 2. doi: 10.1038/s41698-021-00153-8

PMCID:: PMC7925679

Abstract Article PDF–3.8M

Select item 74535119.

PRMT6 serves an oncogenic role in lung adenocarcinoma via regulating p18

Jie Tang, Qinge Meng, Ruirui Shi, Youqi Xu

Mol Med Rep. 2020 Oct; 22(4): 3161–3172. Published online 2020 Aug 3. doi: 10.3892/mmr.2020.11402

PMCID:: PMC7453511

Abstract Article PDF–1.8M

Select item 742732710.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 730149911.

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease

Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu

Transl Neurodegener. 2020; 9: 26. Published online 2020 Jun 18. doi: 10.1186/s40035-020-00206-1

PMCID:: PMC7301499

Abstract Article PDF–14M

Select item 726427312.

A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor

Carla Eller, Laura Heydmann, Che C. Colpitts, Houssein El Saghire, Federica Piccioni, Frank Jühling, Karim Majzoub, Caroline Pons, Charlotte Bach, Julie Lucifora, Joachim Lupberger, Michael Nassal, Glenn S. Cowley, Naoto Fujiwara, Sen-Yung Hsieh, Yujin Hoshida, Emanuele Felli, Patrick Pessaux, Camille Sureau, Catherine Schuster, David E. Root, Eloi R. Verrier, Thomas F. Baumert

Nat Commun. 2020; 11: 2707. Published online 2020 Jun 1. doi: 10.1038/s41467-020-16517-w

PMCID:: PMC7264273

Abstract Article PDF–3.0M

Select item 719316813.

miR‐21‐5p promotes cell proliferation and G1/S transition in melanoma by targeting CDKN2C

Zhaohui Yang, Bo Liao, Xiaoyan Xiang, Sha Ke

FEBS Open Bio. 2020 May; 10(5): 752–760. Published online 2020 Mar 24. doi: 10.1002/2211-5463.12819

PMCID:: PMC7193168

Abstract Article PDF–2.2M

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 704878715.

MCL1 binding to the reverse BH3 motif of P18INK4C couples cell survival to cell proliferation

Robert H. Whitaker, William J. Placzek

Cell Death Dis. 2020 Feb; 11(2): 156. Published online 2020 Feb 28. doi: 10.1038/s41419-020-2351-1

PMCID:: PMC7048787

Abstract Article PDF–1.4M

Select item 674264616.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 645349717.

Role of CDKN2C Copy Number in Sporadic Medullary Thyroid Carcinoma

Elizabeth G. Grubbs, Michelle D. Williams, Paul Scheet, Selina Vattathil, Nancy D. Perrier, Jeffrey E. Lee, Robert F. Gagel, Tao Hai, Lei Feng, Maria E. Cabanillas, Gilbert J. Cote

Thyroid. 2016 Nov 1; 26(11): 1553–1562. Published online 2016 Nov 1. doi: 10.1089/thy.2016.0224

PMCID:: PMC6453497

Abstract Article PDF–308K

Select item 629810518.

Ubiquilin 2 modulates ALS/FTD-linked FUS–RNA complex dynamics and stress granule formation

Elizabeth J. Alexander, Amirhossein Ghanbari Niaki, Tao Zhang, Jaya Sarkar, Yang Liu, Raja Sekhar Nirujogi, Akhilesh Pandey, Sua Myong, Jiou Wang

Proc Natl Acad Sci U S A. 2018 Dec 4; 115(49): E11485–E11494. Published online 2018 Nov 15. doi: 10.1073/pnas.1811997115

PMCID:: PMC6298105

Abstract Article PDF–3.7M

Select item 628879419.

Germline and Somatic Mutations in Cyclin-Dependent Kinase Inhibitor Genes CDKN1A, CDKN2B, and CDKN2C in Sporadic Parathyroid Adenomas

Jessica Costa-Guda, Chen-Pang Soong, Vaishali I. Parekh, Sunita K. Agarwal, Andrew Arnold

Horm Cancer. 2013 Oct; 4(5): 301–307. Published online 2013 May 29. doi: 10.1007/s12672-013-0147-9

PMCID:: PMC6288794

Abstract Article PDF–388K

Select item 596370420.

SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression

Chiou-Hong Lin, Stephen Hon-Kit Wong, Jason H. Kurzer, Corina Schneidawind, Michael C. Wei, Jesús Duque-Afonso, Johan Jeong, Xuhui Feng, Michael L. Cleary

Cell Rep. Author manuscript; available in PMC 2018 May 22.

Published in final edited form as: Cell Rep. 2018 Apr 24; 23(4): 1166–1177. doi: 10.1016/j.celrep.2018.03.124

PMCID:: PMC5963704

Abstract Article PDF–1.1M

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