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Select item 109298141.

miR-557 inhibits hepatocellular carcinoma progression through Wnt/β-catenin signaling pathway by targeting RAB10

Xiaoye Cheng, Can Wu, Haocheng Xu, Ruixiang Zou, Taiyuan Li, Shanping Ye

Aging (Albany NY) 2024 Feb 28; 16(4): 3716–3733. Published online 2024 Feb 15. doi: 10.18632/aging.205554

PMCID:: PMC10929814

Abstract Article PDF–2.1M

Select item 108748592.

The LRRK2 kinase substrates RAB8a and RAB10 contribute complementary but distinct disease-relevant phenotypes in human neurons

Adamantios Mamais, Anwesha Sanyal, Austin Fajfer, Catherine G. Zykoski, Michael Guldin, Alexis Riley-DiPaolo, Nitya Subrahmanian, Whitney Gibbs, Steven Lin, Matthew J. LaVoie

Stem Cell Reports. 2024 Feb 13; 19(2): 163–173. Published online 2024 Feb 1. doi: 10.1016/j.stemcr.2024.01.001

PMCID:: PMC10874859

Abstract Article PDF–5.3M

Select item 108681233.

VPS13C regulates phospho-Rab10-mediated lysosomal function in human dopaminergic neurons

Leonie F. Schrӧder, Wesley Peng, Ge Gao, Yvette C. Wong, Michael Schwake, Dimitri Krainc

J Cell Biol. 2024 May 6; 223(5): e202304042. Published online 2024 Feb 15. doi: 10.1083/jcb.202304042

PMCID:: PMC10868123

Abstract Article PDF–6.5M

Select item 108526374.

Identification of Biomarkers Associated With Alzheimer’s Disease by Bioinformatics Analysis

Yanxin Zhao, Wei Tan, Wenhua Sheng, Xiaohong Li

Am J Alzheimers Dis Other Demen. 2016 Mar; 31(2): 163–168. Published online 2015 Jun 16. doi: 10.1177/1533317515588181

PMCID:: PMC10852637

Abstract Article PDF–487K

Select item 108140035.

Coronavirus M Protein Trafficking in Epithelial Cells Utilizes a Myosin Vb Splice Variant and Rab10

Lynne A. Lapierre, Joseph T. Roland, Elizabeth H. Manning, Catherine Caldwell, Honor L. Glenn, Pierre-Olivier Vidalain, Frederic Tangy, Brenda G. Hogue, C. A. M. de Haan, James R. Goldenring

Cells. 2024 Jan; 13(2): 126. Published online 2024 Jan 10. doi: 10.3390/cells13020126

PMCID:: PMC10814003

Abstract Article PDF–6.8M

Select item 107265436.

Cellular and subcellular localization of Rab10 and phospho-T73 Rab10 in the mouse and human brain

Vijay Singh, Marissa A. Menard, Geidy E. Serrano, Thomas G. Beach, Hien T. Zhao, Alexis Riley-DiPaolo, Nitya Subrahmanian, Matthew J. LaVoie, Laura A. Volpicelli-Daley

Acta Neuropathol Commun. 2023; 11: 201. Published online 2023 Dec 18. doi: 10.1186/s40478-023-01704-9

PMCID:: PMC10726543

Abstract Article PDF–4.7M

Select item 106277867.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 105658768.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105021499.

RAB10 promotes breast cancer proliferation migration and invasion predicting a poor prognosis for breast cancer

Jian Zhuo, Jianjun Han, Yanchun Zhao, Ruiying Hao, Chong shen, He Li, Luxian Dai, Ankang Sheng, Hanyu Yao, Xiaohong Yang, Weiguang Liu

Sci Rep. 2023; 13: 15252. Published online 2023 Sep 14. doi: 10.1038/s41598-023-42434-1

PMCID:: PMC10502149

Abstract Article PDF–5.6M

Select item 1048053510.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1023742211.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1015161512.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 997863513.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 983107814.

Exosomal miR-10527-5p Inhibits Migration, Invasion, Lymphangiogenesis and Lymphatic Metastasis by Affecting Wnt/β-Catenin Signaling via Rab10 in Esophageal Squamous Cell Carcinoma

Zhaohua Xiao, Xumei Feng, Yongjia Zhou, Peiwei Li, Junwen Luo, Wenhao Zhang, Jie Zhou, Jiangfeng Zhao, Dong Wang, Yongjie Wang, Zhongxian Tian, Xiaogang Zhao

Int J Nanomedicine. 2023; 18: 95–114. Published online 2023 Jan 6. doi: 10.2147/IJN.S391173

PMCID:: PMC9831078

Abstract Article PDF–15M

Select item 979798815.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 979580716.

Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2

Annarita Miluzio, Alessandro Cuomo, Chiara Cordiglieri, Lorena Donnici, Elisa Pesce, Mauro Bombaci, Matteo Conti, Alessandra Fasciani, Luigi Terracciano, Lara Manganaro, Mirco Toccafondi, Alessandra Scagliola, Stefania Oliveto, Sara Ricciardi, Renata Grifantini, Raffaele De Francesco, Sergio Abrignani, Nicola Manfrini, Stefano Biffo

eBioMedicine. 2023 Jan; 87: 104390. Published online 2022 Dec 28. doi: 10.1016/j.ebiom.2022.104390

PMCID:: PMC9795807

Abstract Article PDF–4.6M

Select item 979439417.

Nonstructural protein 1 widespread RNA decay phenotype varies among coronaviruses

Yahaira Bermudez, Jacob Miles, Mandy Muller

iScience. 2023 Jan 20; 26(1): 105887. Published online 2022 Dec 28. doi: 10.1016/j.isci.2022.105887

PMCID:: PMC9794394

Abstract Article PDF–2.6M

Select item 977255818.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 976969819.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 962912120.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

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