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Select item 107928751.

EMP3 as a prognostic biomarker correlates with EMT in GBM

Li Li, Siyu Xia, Zitong Zhao, Lili Deng, Hanbing Wang, Dongbo Yang, Yizhou Hu, Jingjing Ji, Dayong Huang, Tao Xin

BMC Cancer. 2024; 24: 89. Published online 2024 Jan 17. doi: 10.1186/s12885-023-11796-0

PMCID:: PMC10792875

Abstract Article PDF–5.1M

Select item 106291592.

EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma

Antoni Andreu Martija, Alexandra Krauß, Natalie Bächle, Laura Doth, Arne Christians, Damir Krunic, Martin Schneider, Dominic Helm, Rainer Will, Christian Hartmann, Christel Herold-Mende, Andreas von Deimling, Stefan Pusch

Acta Neuropathol Commun. 2023; 11: 177. Published online 2023 Nov 7. doi: 10.1186/s40478-023-01673-z

PMCID:: PMC10629159

Abstract Article PDF–5.6M

Select item 84462163.

Establishment of a nomogram with EMP3 for predicting clinical outcomes in patients with glioma: A bi‐center study

Anke Zhang, Houshi Xu, Zeyu Zhang, Yibo Liu, Xiaying Han, Ling Yuan, Yunjia Ni, Shiqi Gao, Yuanzhi Xu, Sheng Chen, Junkun Jiang, Yike Chen, Xiaotao Zhang, Meiqing Lou, Jianmin Zhang

CNS Neurosci Ther. 2021 Oct; 27(10): 1238–1250. Published online 2021 Jul 16. doi: 10.1111/cns.13701

PMCID:: PMC8446216

Abstract Article PDF–2.6M

Select item 84355334.

EMP3 negatively modulates breast cancer cell DNA replication, DNA damage repair, and stem-like properties

Kailing Zhou, Yu Sun, Dan Dong, Chenghai Zhao, Wei Wang

Cell Death Dis. 2021 Sep; 12(9): 844. Published online 2021 Sep 12. doi: 10.1038/s41419-021-04140-6

PMCID:: PMC8435533

Abstract Article PDF–4.5M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81566126.

The Multifunctional Role of EMP3 in the Regulation of Membrane Receptors Associated with IDH-Wild-Type Glioblastoma

Antoni Andreu Martija, Stefan Pusch

Int J Mol Sci. 2021 May; 22(10): 5261. Published online 2021 May 17. doi: 10.3390/ijms22105261

PMCID:: PMC8156612

Abstract Article PDF–4.4M

Select item 81068537.

EMP3 mediates glioblastoma‐associated macrophage infiltration to drive T cell exclusion

Qun Chen, Jing Jin, Xin Huang, Fan Wu, Hongguang Huang, Renya Zhan

J Exp Clin Cancer Res. 2021; 40: 160. Published online 2021 May 8. doi: 10.1186/s13046-021-01954-2

PMCID:: PMC8106853

Abstract Article PDF–6.8M

Select item 80955318.

DNA hypermethylation and Aberrant Expression of the EMP3 Gene at 19q13.3 in Human Gliomas

Annegret Kunitz, Marietta Wolter, Jörg Van Den Boom, Jörg Felsberg, Björn Tews, Meinhard Hahn, Axel Benner, Michael Sabel, Peter Lichter, Guido Reifenberger, Andreas Von Deimling, Christian Hartmann

Brain Pathol. 2007 Oct; 17(4): 363–370. Published online 2007 Jul 4. doi: 10.1111/j.1750-3639.2007.00083.x

PMCID:: PMC8095531

Abstract Article PDF–556K

Select item 75265519.

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

Wenjun Lan, Patricia Santofimia-Castaño, Mirna Swayden, Yi Xia, Zhengwei Zhou, Stephane Audebert, Luc Camoin, Can Huang, Ling Peng, Ana Jiménez-Alesanco, Adrián Velázquez-Campoy, Olga Abián, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Vincent Geli, Philippe Soubeyran, José L. Neira, Juan Iovanna

JCI Insight. 2020 Sep 17; 5(18): e138117. Published online 2020 Sep 17. doi: 10.1172/jci.insight.138117

PMCID:: PMC7526551

Abstract Article PDF–9.1M

Select item 739233410.

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells

Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull

PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606

PMCID:: PMC7392334

Abstract Article PDF–2.7M

Select item 736690911.

Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype

Nicole Thornton, Vanja Karamatic Crew, Louise Tilley, Carole A. Green, Chwen Ling Tay, Rebecca E. Griffiths, Belinda K. Singleton, Frances Spring, Piers Walser, Abdul Ghani Alattar, Benjamin Jones, Rosalind Laundy, Jill R. Storry, Mattias Möller, Lorna Wall, Richard Charlewood, Connie M. Westhoff, Christine Lomas-Francis, Vered Yahalom, Ute Feick, Axel Seltsam, Beate Mayer, Martin L. Olsson, David J. Anstee

Nat Commun. 2020; 11: 3569. Published online 2020 Jul 16. doi: 10.1038/s41467-020-17060-4

PMCID:: PMC7366909

Abstract Article PDF–2.3M

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 679381913.

HNMP-1: A Novel Hematopoietic and Neural Membrane Protein Differentially Regulated in Neural Development and Injury

Laurel M. Bolin, Tom McNeil, Linda A. Lucian, Brigitte DeVaux, Karin Franz-Bacon, Daniel M. Gorman, Sandra Zurawski, Richard Murray, Terrill K. McClanahan

J Neurosci. 1997 Jul 15; 17(14): 5493–5502. doi: 10.1523/JNEUROSCI.17-14-05493.1997

PMCID:: PMC6793819

Abstract Article PDF–1.2M

Select item 674264614.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 536241015.

Epithelial membrane protein 3 regulates TGF-β signaling activation in CD44-high glioblastoma

Fu Jun, Jidong Hong, Qin Liu, Yong Guo, Yiwei Liao, Jianghai Huang, Sailan Wen, Liangfang Shen

Oncotarget. 2017 Feb 28; 8(9): 14343–14358. Published online 2016 Aug 5. doi: 10.18632/oncotarget.11102

PMCID:: PMC5362410

Abstract Article PDF–14M

Select item 536227416.

Review of the GAS3 Family of Proteins and their Relevance to Cancer

Negin Ashki, Lynn Gordon, Madhuri Wadehra

Crit Rev Oncog. Author manuscript; available in PMC 2017 Mar 22.

Published in final edited form as: Crit Rev Oncog. 2015; 20(5-6): 435–447. doi: 10.1615/CritRevOncog.v20.i5-6.140

PMCID:: PMC5362274

Abstract Article PDF–493K

Select item 513380917.

PPIC, EMP3 and CHI3L1 Are Novel Prognostic Markers for High Grade Glioma

Yuan-Feng Gao, Tao Zhu, Chen-Xue Mao, Zhi-Xiong Liu, Zhi-Bin Wang, Xiao-Yuan Mao, Ling Li, Ji-Ye Yin, Hong-Hao Zhou, Zhao-Qian Liu

Int J Mol Sci. 2016 Nov; 17(11): 1808. Published online 2016 Oct 28. doi: 10.3390/ijms17111808

PMCID:: PMC5133809

Abstract Article PDF–1.8M

Select item 474149518.

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway

Yi-Hsien Hsieh, Shu-Ching Hsieh, Chien-Hsing Lee, Shun-Fa Yang, Chun-Wen Cheng, Meng-Ju Tang, Chia-Liang Lin, Chu-Liang Lin, Ruey-Hwang Chou

Oncotarget. 2015 Oct 27; 6(33): 34859–34874. Published online 2015 Oct 12. doi: 10.18632/oncotarget.5414

PMCID:: PMC4741495

Abstract Article PDF–4.7M

Select item 462615119.

Epithelial membrane protein 3 functions as an oncogene and is regulated by microRNA-765 in primary breast carcinoma

XIAO CHUN HONG, YUAN JIAN FEN, GUO CHUN YAN, HONG HONG, CAO HONG YAN, LI WEI BING, YU HAI ZHONG

Mol Med Rep. 2015 Nov; 12(5): 6445–6450. Published online 2015 Sep 14. doi: 10.3892/mmr.2015.4326

PMCID:: PMC4626151

Abstract Article PDF–672K

Select item 426658820.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

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