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Select item 110763981.

KIF22 promotes multiple myeloma progression by regulating the CDC25C/CDK1/cyclinB1 pathway

Meng Zhai, Jiyu Miao, Ru Zhang, Rui Liu, Fangmei Li, Ying Shen, Ting Wang, Xuezhu Xu, Gongzhizi Gao, Jinsong Hu, Aili He, Ju Bai

J Cancer Res Clin Oncol. 2024; 150(5): 239. Published online 2024 May 7. doi: 10.1007/s00432-024-05747-w

PMCID:: PMC11076398

Abstract Article PDF–4.9M

Select item 105476472.

Immortalization-upregulated protein promotes pancreatic cancer progression by regulating NPM1/FHL1-mediated cell-cycle-checkpoint protein activity

Qiankun Luo, Yanfeng Pan, Qiang Fu, Xu Zhang, Shuai Zhou, Pengfei Yu, Huiyuan Tian, Pan Liu, Song Chen, Hongwei Zhang, Tao Qin

Cell Biol Toxicol. 2023; 39(5): 2069–2087. Published online 2022 Feb 10. doi: 10.1007/s10565-022-09695-4

PMCID:: PMC10547647

Abstract Article PDF–9.5M

Select item 94819333.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 92759234.

CDC25C is a prognostic biomarker and correlated with mitochondrial homeostasis in pancreatic adenocarcinoma

Chaoting Zhou, Luyang Wang, Wanye Hu, Lusheng Tang, Ping Zhang, Yan Gao, Jing Du, Yanchun Li, Ying Wang

Bioengineered. 2022; 13(5): 13089–13107. Published online 2022 May 26. doi: 10.1080/21655979.2022.2078940

PMCID:: PMC9275923

Abstract Article PDF–8.4M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 85138536.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80278458.

Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress

Katharine J. Herbert, Rathi Puliyadi, Remko Prevo, Gonzalo Rodriguez-Berriguete, Anderson Ryan, Kristijan Ramadan, Geoff S. Higgins

Cell Death Differ. 2021 Apr; 28(4): 1333–1346. Published online 2020 Nov 9. doi: 10.1038/s41418-020-00655-1

PMCID:: PMC8027845

Abstract Article PDF–2.9M

Select item 76571309.

HY‐1 induces G₂ / M cell cycle arrest in human colon cancer cells through the ATR‐Chk1‐Cdc25C and Weel pathways

Yu Zhao, Zhonghua Wu, Yuting Zhang, Li Zhu

Cancer Sci. 2013 Aug; 104(8): 1062–1066. Published online 2013 May 15. doi: 10.1111/cas.12182

PMCID:: PMC7657130

Abstract Article PDF–817K

Select item 760781010.

Identification of CDC25C as a Potential Biomarker in Hepatocellular Carcinoma Using Bioinformatics Analysis

Ruifeng Xun, Hougen Lu, Xianwang Wang

Technol Cancer Res Treat. 2020; 19: 1533033820967474. Published online 2020 Oct 28. doi: 10.1177/1533033820967474

PMCID:: PMC7607810

Abstract Article PDF–1018K

Select item 721259011.

Different p53 genotypes regulating different phosphorylation sites and subcellular location of CDC25C associated with the formation of polyploid giant cancer cells

Kai Liu, Minying Zheng, Qi Zhao, Kexin Zhang, Zugui Li, Fangmei Fu, Hao Zhang, Jiaxing Du, Yuwei Li, Shiwu Zhang

J Exp Clin Cancer Res. 2020; 39: 83. Published online 2020 May 11. doi: 10.1186/s13046-020-01588-w

Correction in:: J Exp Clin Cancer Res. 2024; 43: 229.

PMCID:: PMC7212590

Abstract Article PDF–6.3M

Select item 719341912.

Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation

Xinfang Yu, Wei Li, Haidan Liu, Qipan Deng, Xu Wang, Hui Hu, Zijun Y. Xu-Monette, Wei Xiong, Zhongxin Lu, Ken H. Young, Wei Wang, Yong Li

J Hematol Oncol. 2020; 13: 40. Published online 2020 May 1. doi: 10.1186/s13045-020-00869-3

PMCID:: PMC7193419

Abstract Article PDF–8.9M

Select item 659455113.

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin

Cell Rep. Author manuscript; available in PMC 2019 Jun 26.

Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060

PMCID:: PMC6594551

Abstract Article PDF–1.4M

Select item 649693014.

miR‐142‐3p inhibits cancer cell proliferation by targeting CDC25C

Xu‐Chen Cao, Yue Yu, Li‐Kun Hou, Xiao‐Hu Sun, Jie Ge, Bin Zhang, Xin Wang

Cell Prolif. 2016 Feb; 49(1): 58–68. Published online 2016 Jan 25. doi: 10.1111/cpr.12235

PMCID:: PMC6496930

Abstract Article PDF–1.2M

Select item 627071015.

Therapeutic Targeting the Cell Division Cycle 25 (CDC25) Phosphatases in Human Acute Myeloid Leukemia — The Possibility to Target Several Kinases through Inhibition of the Various CDC25 Isoforms

Annette K. Brenner, Håkon Reikvam, Antonio Lavecchia, Øystein Bruserud

Molecules. 2014 Nov; 19(11): 18414–18447. Published online 2014 Nov 12. doi: 10.3390/molecules191118414

PMCID:: PMC6270710

Abstract Article PDF–777K

Select item 608687416.

Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells

Changjie Wu, Junfang Lyu, Eun Ju Yang, Yifan Liu, Baoyuan Zhang, Joong Sup Shim

Nat Commun. 2018; 9: 3212. Published online 2018 Aug 10. doi: 10.1038/s41467-018-05694-4

PMCID:: PMC6086874

Abstract Article PDF–2.7M

Select item 600345917.

Deubiquitinating enzyme USP3 controls CHK1 chromatin association and activation

Yu-Che Cheng, Sheau-Yann Shieh

Proc Natl Acad Sci U S A. 2018 May 22; 115(21): 5546–5551. Published online 2018 May 7. doi: 10.1073/pnas.1719856115

PMCID:: PMC6003459

Abstract Article PDF–1.5M

Select item 600285418.

Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase

LE Giono, L Resnick-Silverman, LA Carvajal, S St Clair, JJ Manfredi

Oncogene. Author manuscript; available in PMC 2018 Jun 15.

Published in final edited form as: Oncogene. 2017 Dec 7; 36(49): 6762–6773. Published online 2017 Aug 14. doi: 10.1038/onc.2017.254

PMCID:: PMC6002854

Abstract Article PDF–860K

Select item 589259519.

Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G₂/M-phase transition

Yuqing Shen, John William Sherman, Xuyong Chen, Ruoning Wang

J Biol Chem. 2018 Apr 6; 293(14): 5185–5199. Published online 2018 Feb 21. doi: 10.1074/jbc.RA117.001379

PMCID:: PMC5892595

Abstract Article PDF–2.6M

Select item 566346520.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

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PMC Links for GEO Profiles (Select 50684015) (102)
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Homo sapiens cDNA clone IMAGE:5267399
Homo sapiens cDNA clone IMAGE:5267399
gi|26251830|gb|BC040571.1|

Nucleotide
Gene Links for GEO Profiles (Select 2932787) (1)
Gene
SORBS2 sorbin and SH3 domain containing 2 [Homo sapiens]
SORBS2 sorbin and SH3 domain containing 2 [Homo sapiens]
Gene ID:8470

Gene
SLC25A20 solute carrier family 25 member 20 [Homo sapiens]
SLC25A20 solute carrier family 25 member 20 [Homo sapiens]
Gene ID:788

Gene

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