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Select item 111316941.

Regulation of turnover of tumor suppressor p53 and cell growth by E6-AP, a ubiquitin protein ligase mutated in Angelman mental retardation syndrome

A. Mishra, N. R. Jana

Cell Mol Life Sci. 2008 Feb; 65(4): 656–666. Published online 2008 Jan 12. doi: 10.1007/s00018-007-7476-1

PMCID:: PMC11131694

Abstract Article PDF–1.3M

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 106176733.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105658764.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104765615.

UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells

Yanyan Luo, Yun Yang, Cong Yang, Chuanyin Li, Ronggui Hu, Wujun Geng, Xianhui Kang, Hai Lin

FEBS Open Bio. 2023 Sep; 13(9): 1756–1771. Published online 2023 Jul 28. doi: 10.1002/2211-5463.13675

PMCID:: PMC10476561

Abstract Article PDF–5.1M

Select item 104305976.

Ubiquitin-protein ligase E3A (UBE3A) mediation of viral infection and human diseases

Pankaj Chaudhary, Jessica Proulx, In-Woo Park

Virus Res. 2023 Oct 2; 335: 199191. Published online 2023 Aug 4. doi: 10.1016/j.virusres.2023.199191

PMCID:: PMC10430597

Abstract Article PDF–4.4M

Select item 104099787.

MiR-218-5p promotes trophoblast infiltration and inhibits endoplasmic reticulum/oxidative stress by reducing UBE3A-mediated degradation of SATB1

Xiao Gu, Xiaomei Sun, Yanling Yu, Lei Li

J Cell Commun Signal. 2023 Sep; 17(3): 993–1008. Published online 2023 May 16. doi: 10.1007/s12079-023-00751-0

PMCID:: PMC10409978

Abstract Article PDF–10M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101475519.

The role of UBE3A in the autism and epilepsy-related Dup15q syndrome using patient-derived, CRISPR-corrected neurons

Marwa Elamin, Aurelie Dumarchey, Christopher Stoddard, Tiwanna M. Robinson, Christopher Cowie, Dea Gorka, Stormy J. Chamberlain, Eric S. Levine

Stem Cell Reports. 2023 Apr 11; 18(4): 884–898. Published online 2023 Mar 9. doi: 10.1016/j.stemcr.2023.02.002

PMCID:: PMC10147551

Abstract Article PDF–3.6M

Select item 1008196510.

E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure

Gwen R. Buel, Xiang Chen, Wazo Myint, Olumide Kayode, Varvara Folimonova, Anthony Cruz, Katarzyna A Skorupka, Hiroshi Matsuo, Kylie J. Walters

Structure. Author manuscript; available in PMC 2024 Apr 6.

Published in final edited form as: Structure. 2023 Feb 14 : S0969-2126(23)00033-3. Published online 2023 Feb 14. doi: 10.1016/j.str.2023.01.012

PMCID:: PMC10081965

Abstract Article PDF–3.1M

Select item 1008090811.

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy

BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4

PMCID:: PMC10080908

Abstract Article PDF–3.2M

Select item 1007759512.

Effects of UBE3A on Cell and Liver Metabolism through the Ubiquitination of PDHA1 and ACAT1

Kangli Peng, Shirong Wang, Ruochuan Liu, Li Zhou, Geon H. Jeong, In Ho Jeong, Xianpeng Liu, Hiroaki Kiyokawa, Bingzhong Xue, Bo Zhao, Hang Shi, Jun Yin

Biochemistry. 2023 Apr 4; 62(7): 1274–1286. Published online 2023 Mar 15. doi: 10.1021/acs.biochem.2c00624

PMCID:: PMC10077595

Abstract Article PDF–7.0M

Select item 982046013.

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome

Eva M. G. Viho, A. Mattijs Punt, Ben Distel, René Houtman, Jan Kroon, Ype Elgersma, Onno C. Meijer

Int J Mol Sci. 2023 Jan; 24(1): 303. Published online 2022 Dec 24. doi: 10.3390/ijms24010303

PMCID:: PMC9820460

Abstract Article PDF–3.4M

Select item 976969814.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 960965815.

Tumor Suppressor p53 Inhibits Hepatitis B Virus Replication by Downregulating HBx via E6AP-Mediated Proteasomal Degradation in Human Hepatocellular Carcinoma Cell Lines

Ha-Yeon Lim, Jiwoo Han, Hyunyoung Yoon, Kyung Lib Jang

Viruses. 2022 Oct; 14(10): 2313. Published online 2022 Oct 21. doi: 10.3390/v14102313

PMCID:: PMC9609658

Abstract Article PDF–3.6M

Select item 948193316.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 948160217.

Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function

Simon Maria Kienle, Tobias Schneider, Katrin Stuber, Christoph Globisch, Jasmin Jansen, Florian Stengel, Christine Peter, Andreas Marx, Michael Kovermann, Martin Scheffner

Nat Commun. 2022; 13: 5435. Published online 2022 Sep 16. doi: 10.1038/s41467-022-33087-1

PMCID:: PMC9481602

Abstract Article PDF–3.7M

Select item 934857618.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 930341819.

Generation and Characterization of Site‐Specifically Mono‐Ubiquitylated p53

Dr. Alexandra Julier, Dr. Vanessa Radtke, Prof. Dr. Andreas Marx, Prof. Dr. Martin Scheffner

Chembiochem. 2022 Mar 18; 23(6): e202100659. Published online 2022 Feb 3. doi: 10.1002/cbic.202100659

PMCID:: PMC9303418

Abstract Article PDF–688K

Select item 927928520.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

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