PMC Links for GEO Profiles (Select 53115005) - PMC

Jordan D. Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W. Todd, Ying Hao, Ziyi Li, Zachary T. McEachin, Anantharaman Shantaraman, Duc M. Duong, Lillian M. Daughrity, Karen Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T. Lilley, Megan H. Donahue, Vidhya Maheswari Jawahar, Bradley F. Boeve, Ronald C. Petersen, David S. Knopman, Björn Oskarsson, Neill R. Graff-Radford, Zbigniew K. Wszolek, Dennis W. Dickson, Keith A. Josephs, Yue A. Qi, Nicholas T. Seyfried, Michael E. Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N. Cook

Sci Transl Med. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Sci Transl Med. 2024 Jan 17; 16(730): eadf9735. Published online 2024 Jan 17. doi: 10.1126/scitranslmed.adf9735

PMCID:: PMC10841341

Abstract Article PDF–1.7M

Select item 105455065.

C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes

Cristina T. Vicente, Jolien Perneel, Sarah Wynants, Bavo Heeman, Marleen Van den Broeck, Matt Baker, Simon Cheung, Júlia Faura, Ian R A Mackenzie, Rosa Rademakers

Brain. 2023 Oct; 146(10): 4055–4064. Published online 2023 Apr 26. doi: 10.1093/brain/awad133

PMCID:: PMC10545506

Abstract Article PDF–570K

Select item 105284786.

TMEM106B Fibrils from FTLD Patients and Healthy Controls

James D. Greenwood, Wyatt C. Powell, Maciej A. Walczak

ACS Chem Neurosci. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: ACS Chem Neurosci. 2023 Aug 16; 14(16): 2827–2829. Published online 2023 Aug 2. doi: 10.1021/acschemneuro.3c00482

PMCID:: PMC10528478

Abstract Article PDF–822K

Select item 105101317.

The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus

Jun Yup Lee, Dylan J Harney, Jonathan D Teo, John B Kwok, Greg T. Sutherland, Mark Larance, Anthony S Don

Mol Neurodegener. 2023; 18: 63. Published online 2023 Sep 19. doi: 10.1186/s13024-023-00650-3

Correction in:: Mol Neurodegener. 2024; 19: 21.

PMCID:: PMC10510131

Abstract Article PDF–4.0M

Select item 104135488.

TMEM106B aggregation in neurodegenerative diseases: linking genetics to function

Hai-Shan Jiao, Peng Yuan, Jin-Tai Yu

Mol Neurodegener. 2023; 18: 54. Published online 2023 Aug 10. doi: 10.1186/s13024-023-00644-1

PMCID:: PMC10413548

Abstract Article PDF–2.1M

Select item 104094969.

TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry

Jim Baggen, Maarten Jacquemyn, Leentje Persoons, Els Vanstreels, Valerie E. Pye, Antoni G. Wrobel, Valeria Calvaresi, Stephen R. Martin, Chloë Roustan, Nora B. Cronin, Eamonn Reading, Hendrik Jan Thibaut, Thomas Vercruysse, Piet Maes, Frederik De Smet, Angie Yee, Toey Nivitchanyong, Marina Roell, Natalia Franco-Hernandez, Herve Rhinn, Alusha Andre Mamchak, Maxime Ah Young-Chapon, Eric Brown, Peter Cherepanov, Dirk Daelemans

Cell. 2023 Aug 3; 186(16): 3427–3442.e22. doi: 10.1016/j.cell.2023.06.005

PMCID:: PMC10409496

Abstract Article PDF–13M

Select item 1023742210.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 984499311.

Amyloid fibrils in disease FTLD-TDP are composed of TMEM106B not TDP-43

Yi Xiao Jiang, Qin Cao, Michael R. Sawaya, Romany Abskharon, Peng Ge, Michael DeTure, Dennis W. Dickson, Janine Y. Fu, Rachel R. Ogorzalek Loo, Joseph A. Loo, David S. Eisenberg

Nature. Author manuscript; available in PMC 2023 Jan 17.

Published in final edited form as: Nature. 2022 May; 605(7909): 304–309. Published online 2022 Mar 28. doi: 10.1038/s41586-022-04670-9

PMCID:: PMC9844993

Abstract Article PDF–5.7M

Select item 954779912.

Identification of TMEM106B amyloid fibrils provides an updated view of TMEM106B biology in health and disease

Jolien Perneel, Rosa Rademakers

Acta Neuropathol. 2022; 144(5): 807–819. Published online 2022 Sep 2. doi: 10.1007/s00401-022-02486-5

PMCID:: PMC9547799

Abstract Article PDF–4.5M

Select item 940888513.

TMEM106B Acts as a Modifier of Cognitive and Motor Functions in Amyotrophic Lateral Sclerosis

Arianna Manini, Antonia Ratti, Alberto Brusati, Alessio Maranzano, Isabella Fogh, Silvia Peverelli, Stefano Messina, Davide Gentilini, Federico Verde, Barbara Poletti, Claudia Morelli, Vincenzo Silani, Nicola Ticozzi

Int J Mol Sci. 2022 Aug; 23(16): 9276. Published online 2022 Aug 17. doi: 10.3390/ijms23169276

PMCID:: PMC9408885

Abstract Article PDF–772K

Select item 927928514.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 923162315.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 917141116.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 911973617.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 909548218.

Age-dependent formation of TMEM106B amyloid filaments in human brains

Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J. Garringer, Ruben Vidal, Grace I. Hallinan, Kathy L. Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G. Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G. Murzin, Michel Goedert, Sjors H. W. Scheres

Nature. 2022; 605(7909): 310–314. Published online 2022 Mar 28. doi: 10.1038/s41586-022-04650-z

PMCID:: PMC9095482

Abstract Article PDF–18M

Select item 903755419.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 901856320.

Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases

Andrew Chang, Xinyu Xiang, Jing Wang, Carolyn Lee, Tamta Arakhamia, Marija Simjanoska, Chi Wang, Yari Carlomagno, Guoan Zhang, Shikhar Dhingra, Manon Thierry, Jolien Perneel, Bavo Heeman, Lauren M. Forgrave, Michael DeTure, Mari L. DeMarco, Casey N. Cook, Rosa Rademakers, Dennis Dickson, Leonard Petrucelli, Michael H. B. Stowell, Ian R. A. Mackenzie, Anthony W. P. Fitzpatrick

Cell. Author manuscript; available in PMC 2023 Apr 14.

Published in final edited form as: Cell. 2022 Apr 14; 185(8): 1346–1355.e15. Published online 2022 Mar 4. doi: 10.1016/j.cell.2022.02.026

PMCID:: PMC9018563

Abstract Article PDF–2.0M

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