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Select item 107898021.

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis

Linnea Z. Drexhage, Shengpan Zhang, Maeva Dupont, Franziska Ragaller, Ellen Sjule, Jose Cabezas-Caballero, Lachlan P. Deimel, Helen Robertson, Rebecca A. Russell, Omer Dushek, Erdinc Sezgin, Niloofar Karaji, Quentin J. Sattentau

Nat Commun. 2024; 15: 541. Published online 2024 Jan 15. doi: 10.1038/s41467-023-44619-8

PMCID:: PMC10789802

Abstract Article PDF–1.8M

Select item 103293312.

Combined proteomics and CRISPR‒Cas9 screens in PDX identify ADAM10 as essential for leukemia in vivo

Ehsan Bahrami, Jan Philipp Schmid, Vindi Jurinovic, Martin Becker, Anna-Katharina Wirth, Romina Ludwig, Sophie Kreissig, Tania Vanessa Duque Angel, Diana Amend, Katharina Hunt, Rupert Öllinger, Roland Rad, Joris Maximilian Frenz, Maria Solovey, Frank Ziemann, Matthias Mann, Binje Vick, Christian Wichmann, Tobias Herold, Ashok Kumar Jayavelu, Irmela Jeremias

Mol Cancer. 2023; 22: 107. Published online 2023 Jul 8. doi: 10.1186/s12943-023-01803-0

PMCID:: PMC10329331

Abstract Article PDF–5.5M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101528684.

ADAM10 Gene Polymorphism and Its Relationship to Hepatocellular Carcinoma in Egyptian HCV Patients Receiving Direct-Acting Antiviral Therapies (DAAs)

Samar Ghanem, Gamalat El Gedawy, Sania Yehia, Hanan Bedair, Samah Awad, Wael Abdel-Razek, Mostafa Elhelbawy, Dalia EL-Sabaawy, Ashraf Yousif Elfert

Asian Pac J Cancer Prev. 2023; 24(1): 149–155. doi: 10.31557/APJCP.2023.24.1.149

PMCID:: PMC10152868

Abstract Article PDF–327K

Select item 101391145.

ADAM10 and ADAM17, Major Regulators of Chronic Kidney Disease Induced Atherosclerosis?

Sanne L. Maas, Marjo M. P. C. Donners, Emiel P. C. van der Vorst

Int J Mol Sci. 2023 Apr; 24(8): 7309. Published online 2023 Apr 15. doi: 10.3390/ijms24087309

PMCID:: PMC10139114

Abstract Article PDF–2.1M

Select item 100982926.

Potential impact of ADAM‐10 genetic variants with the clinical features of oral squamous cell carcinoma

Yi‐Tzu Chen, Chiao‐Wen Lin, Ying‐Erh Chou, Shih‐Chi Su, Lun‐Ching Chang, Chia‐Yi Lee, Ming‐Ju Hsieh, Shun‐Fa Yang

J Cell Mol Med. 2023 Apr; 27(8): 1144–1152. Published online 2023 Mar 22. doi: 10.1111/jcmm.17728

PMCID:: PMC10098292

Abstract Article PDF–1.3M

Select item 100939277.

ADAM10 Gene Variants in AD Patients and Their Relationship to CSF Protein Levels

Pablo Agüero-Rabes, Julián Pérez-Pérez, Lucía Cremades-Jimeno, María-Salud García-Ayllón, Adriana Gea-González, María José Sainz, Ignacio Mahillo-Fernández, Raquel Téllez, Blanca Cárdaba, Javier Sáez-Valero, Estrella Gómez-Tortosa

Int J Mol Sci. 2023 Apr; 24(7): 6113. Published online 2023 Mar 24. doi: 10.3390/ijms24076113

PMCID:: PMC10093927

Abstract Article PDF–1.3M

Select item 99170058.

Elevated Expression of ADAM10 in Skeletal Muscle of Patients with Idiopathic Inflammatory Myopathies Could Be Responsible for FNDC5/Irisin Unbalance

Roberta Zerlotin, Marco Fornaro, Mariella Errede, Patrizia Pignataro, Clelia Suriano, Maddalena Ruggieri, Silvia Colucci, Florenzo Iannone, Maria Grano, Graziana Colaianni

Int J Mol Sci. 2023 Feb; 24(3): 2469. Published online 2023 Jan 27. doi: 10.3390/ijms24032469

PMCID:: PMC9917005

Abstract Article PDF–3.8M

Select item 98135479.

ADAM10 mediates shedding of carbonic anhydrase IX ectodomain non-redundantly to ADAM17

Miriam Zatovicova, Ivana Kajanova, Martina Takacova, Lenka Jelenska, Olga Sedlakova, Martina Labudova, Silvia Pastorekova

Oncol Rep. 2023 Feb; 49(2): 27. Published online 2022 Dec 15. doi: 10.3892/or.2022.8464

PMCID:: PMC9813547

Abstract Article PDF–1.2M

Select item 960404110.

ADAM10 and ADAM17—Novel Players in Retinoblastoma Carcinogenesis

Dario Van Meenen, Annika Doege, Emily Alefeld, André Haase, Manfred Beier, Tobias Kiefer, Eva Biewald, Klaus Metz, Oliver Dräger, Maike Anna Busch, Nicole Dünker

Int J Mol Sci. 2022 Oct; 23(20): 12621. Published online 2022 Oct 20. doi: 10.3390/ijms232012621

PMCID:: PMC9604041

Abstract Article PDF–7.5M

Select item 927961111.

Role of ADAM10 and ADAM17 in the Regulation of Keratinocyte Adhesion in Pemphigus Vulgaris

Daniela Kugelmann, Maresa Anders, Anna M. Sigmund, Desalegn T. Egu, Ramona A. Eichkorn, Amir S. Yazdi, Miklós Sárdy, Michael Hertl, Dario Didona, Takashi Hashimoto, Jens Waschke

Front Immunol. 2022; 13: 884248. Published online 2022 Jun 30. doi: 10.3389/fimmu.2022.884248

PMCID:: PMC9279611

Abstract Article PDF–9.0M

Select item 923162312.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 917141113.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 917140914.

ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion

Georg Jocher, Vincent Grass, Sarah K Tschirner, Lydia Riepler, Stephan Breimann, Tuğberk Kaya, Madlen Oelsner, M Sabri Hamad, Laura I Hofmann, Carl P Blobel, Carsten B Schmidt‐Weber, Ozgun Gokce, Constanze A Jakwerth, Jakob Trimpert, Janine Kimpel, Andreas Pichlmair, Stefan F Lichtenthaler

EMBO Rep. 2022 Jun; 23(6): e54305. Published online 2022 May 8. doi: 10.15252/embr.202154305

PMCID:: PMC9171409

Abstract Article PDF–2.1M

Select item 912732815.

The transmembrane domain of the amyloid precursor protein is required for antiamyloidogenic processing by α-secretase ADAM10

Lisa Hitschler, Thorsten Lang

J Biol Chem. 2022 Jun; 298(6): 101911. Published online 2022 Apr 7. doi: 10.1016/j.jbc.2022.101911

PMCID:: PMC9127328

Abstract Article PDF–2.7M

Select item 911973616.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910523517.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 909848518.

ADAM10-cleaved ephrin-A5 contributes to prostate cancer metastasis

Chenchen Cai, Miaomiao Zhang, Lei Liu, Haoliang Zhang, Yi Guo, Ting Lan, Yinhai Xu, Ping Ma, Shibao Li

Cell Death Dis. 2022 May; 13(5): 453. Published online 2022 May 12. doi: 10.1038/s41419-022-04893-8

PMCID:: PMC9098485

Abstract Article PDF–4.9M

Select item 883598019.

Pseudomonas aeruginosa Triggered Exosomal Release of ADAM10 Mediates Proteolytic Cleavage in Trans

Ahmad Aljohmani, Bastian Opitz, Markus Bischoff, Daniela Yildiz

Int J Mol Sci. 2022 Feb; 23(3): 1259. Published online 2022 Jan 23. doi: 10.3390/ijms23031259

PMCID:: PMC8835980

Abstract Article PDF–3.0M

Select item 883596120.

Analysis of mRNA and Protein Levels of CAP2, DLG1 and ADAM10 Genes in Post-Mortem Brain of Schizophrenia, Parkinson’s and Alzheimer’s Disease Patients

Anna Di Maio, Arianna De Rosa, Silvia Pelucchi, Martina Garofalo, Benedetta Marciano, Tommaso Nuzzo, Fabrizio Gardoni, Andrea M. Isidori, Monica Di Luca, Francesco Errico, Andrea De Bartolomeis, Elena Marcello, Alessandro Usiello

Int J Mol Sci. 2022 Feb; 23(3): 1539. Published online 2022 Jan 28. doi: 10.3390/ijms23031539

PMCID:: PMC8835961

Abstract Article PDF–2.4M

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