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Select item 110277931.

Ring domains are essential for GATOR2-dependent mTORC1 activation

Cong Jiang, Xiaoming Dai, Shaohui He, Hongfei Zhou, Lan Fang, Jianping Guo, Songlei Liu, Tao Zhang, Weijuan Pan, Haihong Yu, Tianmin Fu, Dali Li, Hiroyuki Inuzuka, Ping Wang, Jianru Xiao, Wenyi Wei

Mol Cell. Author manuscript; available in PMC 2024 Apr 19.

Published in final edited form as: Mol Cell. 2023 Jan 5; 83(1): 74–89.e9. Published online 2022 Dec 16. doi: 10.1016/j.molcel.2022.11.021

PMCID:: PMC11027793

Abstract Article PDF–3.0M

Select item 109910442.

Sestrin2 ameliorates diabetic retinopathy by regulating autophagy and ferroptosis

Xiaoting Xi, Qianbo Chen, Jia Ma, Xuewei Wang, Junyan Zhang, Yan Li

J Mol Histol. 2024; 55(2): 169–184. Published online 2024 Jan 2. doi: 10.1007/s10735-023-10180-3

Correction in:: J Mol Histol. 2024; 55(2): 185.

PMCID:: PMC10991044

Abstract Article PDF–2.7M

Select item 108805333.

Sestrin 2 protects human lens epithelial cells from oxidative stress and apoptosis induced by hydrogen peroxide by regulating the mTOR/Nrf2 pathway

Xiao Tian, Jie Wei

Int J Immunopathol Pharmacol. 2024 Jan-Dec; 38: 03946320241234741. Published online 2024 Feb 20. doi: 10.1177/03946320241234741

PMCID:: PMC10880533

Abstract Article PDF–2.4M

Select item 106855034.

Significance of serum sestrin2 as a biomarker of severity and functional outcome in acute intracerebral hemorrhage: a prospective observational longitudinal study

Xianghong Dou, Wensheng Dong, Yanmei Gu, Tingting Zhang, Jianhua Zhang

BMC Neurol. 2023; 23: 424. Published online 2023 Nov 29. doi: 10.1186/s12883-023-03470-6

PMCID:: PMC10685503

Abstract Article PDF–1.5M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100480656.

SESN2 Could Be a Potential Marker for Diagnosis and Prognosis in Glioma

Lingdan Xu, Zelin Liu, Huihui Wang, Jiyuan Lu, Jia Xu, Yucheng Meng, Ke Huang, Bin Liu

Genes (Basel) 2023 Mar; 14(3): 701. Published online 2023 Mar 12. doi: 10.3390/genes14030701

PMCID:: PMC10048065

Abstract Article PDF–5.9M

Select item 100035177.

Sestrin2 as a Protective Shield against Cardiovascular Disease

Muhammad Ammar Zahid, Shahenda Salaheldin Abdelsalam, Hicham Raïq, Aijaz Parray, Hesham Mohamed Korashy, Asad Zeidan, Mohamed A. Elrayess, Abdelali Agouni

Int J Mol Sci. 2023 Mar; 24(5): 4880. Published online 2023 Mar 2. doi: 10.3390/ijms24054880

PMCID:: PMC10003517

Abstract Article PDF–5.0M

Select item 99683438.

Sestrin2: multifaceted functions, molecular basis, and its implications in liver diseases

Chunfeng Lu, Yiming Jiang, Wenxuan Xu, Xiaofeng Bao

Cell Death Dis. 2023 Feb; 14(2): 160. Published online 2023 Feb 25. doi: 10.1038/s41419-023-05669-4

PMCID:: PMC9968343

Abstract Article PDF–3.1M

Select item 95365299.

Sestrin2 Is Increased in Calcific Aortic Disease and Inhibits Osteoblastic Differentiation in Valvular Interstitial Cells via the Nuclear Factor E2–related Factor 2 Pathway

Haixiong Wang, Jicheng Xi, Zhibiao Zhang, Jun Li, Liping Guo, Na Li, Yuehui Sun, Xiaofang Li, Xuebin Han

J Cardiovasc Pharmacol. 2022 Oct; 80(4): 609–615. Published online 2022 Jun 14. doi: 10.1097/FJC.0000000000001314

PMCID:: PMC9536529

Abstract Article PDF–612K

Select item 946459210.

Structure of the nutrient-sensing hub GATOR2

Max L. Valenstein, Kacper B. Rogala, Pranav V. Lalgudi, Edward J. Brignole, Xin Gu, Robert A. Saxton, Lynne Chantranupong, Jonas Kolibius, Jan-Philipp Quast, David M. Sabatini

Nature. Author manuscript; available in PMC 2023 Jan 13.

Published in final edited form as: Nature. 2022 Jul; 607(7919): 610–616. Published online 2022 Jul 13. doi: 10.1038/s41586-022-04939-z

PMCID:: PMC9464592

Abstract Article PDF–6.9M

Select item 942690111.

Sestrin 2 levels are associated with emphysematous phenotype of COPD

Leonidas Angelakis, Andriana I. Papaioannou, Evgenia Papathanasiou, Argiro Mazioti, Maria Kallieri, George Papatheodorou, George Patentalakis, Georgios Hillas, Spyridon Papiris, Nikolaos Koulouris, Stelios Loukides, Petros Bakakos

PLoS One. 2022; 17(8): e0273652. Published online 2022 Aug 30. doi: 10.1371/journal.pone.0273652

PMCID:: PMC9426901

Abstract Article PDF–906K

Select item 917321012.

Possible roles of sestrin2 in multiple sclerosis and its relationships with clinical outcomes

Faruk Omer ODABAS, Ali Ulvi UCA, Turan AKDAG, Filiz DEMİRDÖGEN, Mustafa ALTAS, Osman Serhat TOKGOZ

Arq Neuropsiquiatr. 2022 Apr; 80(4): 399–404. Published online 2022 Feb 21. doi: 10.1590/0004-282X-ANP-2021-0202

PMCID:: PMC9173210

Abstract Article PDF–328K

Select item 874523613.

RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival

Kenzui Taniue, Tanzina Tanu, Yuki Shimoura, Shuhei Mitsutomi, Han Han, Rika Kakisaka, Yusuke Ono, Nobue Tamamura, Kenji Takahashi, Youichiro Wada, Yusuke Mizukami, Nobuyoshi Akimitsu

Int J Mol Sci. 2022 Jan; 23(1): 496. Published online 2022 Jan 2. doi: 10.3390/ijms23010496

PMCID:: PMC8745236

Abstract Article PDF–6.0M

Select item 872119114.

The functions and roles of sestrins in regulating human diseases

Yitong Chen, Tingben Huang, Zhou Yu, Qiong Yu, Ying Wang, Ji’an Hu, Jiejun Shi, Guoli Yang

Cell Mol Biol Lett. 2022; 27: 2. Published online 2022 Jan 3. doi: 10.1186/s11658-021-00302-8

PMCID:: PMC8721191

Abstract Article PDF–2.1M

Select item 859583615.

Sestrin2 as a Potential Target for Regulating Metabolic-Related Diseases

Linan Gong, Zanzan Wang, Zhenggui Wang, Zhiguo Zhang

Front Endocrinol (Lausanne) 2021; 12: 751020. Published online 2021 Nov 3. doi: 10.3389/fendo.2021.751020

PMCID:: PMC8595836

Abstract Article PDF–833K

Select item 849099716.

BioID reveals an ATG9A interaction with ATG13‐ATG101 in the degradation of p62/SQSTM1‐ubiquitin clusters

Ashari R Kannangara, Daniel M Poole, Colten M McEwan, Joshua C Youngs, Vajira K Weerasekara, Alex M Thornock, Misael T Lazaro, Eranga R Balasooriya, Laura M Oh, Erik J Soderblom, Jonathan J Lee, Daniel L Simmons, Joshua L Andersen

EMBO Rep. 2021 Oct 5; 22(10): e51136. Published online 2021 Aug 9. doi: 10.15252/embr.202051136

PMCID:: PMC8490997

Abstract Article PDF–4.5M

Select item 841851617.

Sestrin2 and Beclin1 levels in Polycystic Ovary Syndrome

Vahid Saeedi, Mona Nourbakhsh, Mitra Nourbakhsh, Ladan Haghighi, Leila Kamalzadeh, Samira Ezzati Mobasser, Maryam Razzaghy‐Azar

J Clin Lab Anal. 2021 Sep; 35(9): e23957. Published online 2021 Aug 16. doi: 10.1002/jcla.23957

PMCID:: PMC8418516

Abstract Article PDF–459K

Select item 838484818.

SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy

Xiaofan Yang, Pingping Xue, Meng Yuan, Xiang Xu, Cheng Wang, Wenqing Li, Hans-Günther Machens, Zhenbing Chen

Cell Death Dis. 2021 Sep; 12(9): 805. Published online 2021 Aug 24. doi: 10.1038/s41419-021-04094-9

PMCID:: PMC8384848

Abstract Article PDF–16M

Select item 833004019.

Investigation of the levels of circulating miR-29a, miR-122, sestrin 2 and inflammatory markers in obese children with/without type 2 diabetes: a case control study

Khalid M. Mohany, Osamah Al Rugaie, Osama Al-Wutayd, Abdullah Al-Nafeesah

BMC Endocr Disord. 2021; 21: 152. Published online 2021 Aug 3. doi: 10.1186/s12902-021-00829-z

PMCID:: PMC8330040

Abstract Article PDF–913K

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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