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Items: 1 to 20 of 22

1.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
2.
DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
L. Robert Hollingsworth, Humayun Sharif, Andrew R. Griswold, Pietro Fontana, Julian Mintseris, Kevin B. Dagbay, Joao A. Paulo, Steven P. Gygi, Daniel A. Bachovchin, Hao Wu
Nature. Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: Nature. 2021 Apr; 592(7856): 778–783. Published online 2021 Mar 17. doi: 10.1038/s41586-021-03350-4
PMCID:
PMC8299537
ArticlePDF–5.5M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
Menghang Huang, Xiaoxiao Zhang, Gee Ann Toh, Qin Gong, Jia Wang, Zhifu Han, Bin Wu, Franklin Zhong, Jijie Chai
Nature. 2021; 592(7856): 773–777. Published online 2021 Mar 17. doi: 10.1038/s41586-021-03320-w
PMCID:
PMC8081665
AbstractArticlePDF–36M
5.
DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes
Darren C. Johnson, Marian C. Okondo, Elizabeth L. Orth, Sahana D. Rao, Hsin-Che Huang, Daniel P. Ball, Daniel A. Bachovchin
Cell Death Dis. 2020 Aug; 11(8): 628. Published online 2020 Aug 14. doi: 10.1038/s41419-020-02865-4
PMCID:
PMC7428001
AbstractArticlePDF–1.4M
6.
DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation
Andrew R. Griswold, Daniel P. Ball, Abir Bhattacharjee, Ashley J. Chui, Sahana D. Rao, Cornelius Y. Taabazuing, Daniel A. Bachovchin
ACS Chem Biol. 2019 Nov 15; 14(11): 2424–2429. Published online 2019 Sep 17. doi: 10.1021/acschembio.9b00462
PMCID:
PMC6862324
AbstractArticlePDF–1.8M
7.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
8.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
9.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Karsten Boldt, Jeroen van Reeuwijk, Qianhao Lu, Konstantinos Koutroumpas, Thanh-Minh T. Nguyen, Yves Texier, Sylvia E. C. van Beersum, Nicola Horn, Jason R. Willer, Dorus A. Mans, Gerard Dougherty, Ideke J. C. Lamers, Karlien L. M. Coene, Heleen H. Arts, Matthew J. Betts, Tina Beyer, Emine Bolat, Christian Johannes Gloeckner, Khatera Haidari, Lisette Hetterschijt, Daniela Iaconis, Dagan Jenkins, Franziska Klose, Barbara Knapp, Brooke Latour, Stef J. F. Letteboer, Carlo L. Marcelis, Dragana Mitic, Manuela Morleo, Machteld M. Oud, Moniek Riemersma, Susan Rix, Paulien A. Terhal, Grischa Toedt, Teunis J. P. van Dam, Erik de Vrieze, Yasmin Wissinger, Ka Man Wu, Gordana Apic, Philip L. Beales, Oliver E. Blacque, Toby J. Gibson, Martijn A. Huynen, Nicholas Katsanis, Hannie Kremer, Heymut Omran, Erwin van Wijk, Uwe Wolfrum, François Kepes, Erica E. Davis, Brunella Franco, Rachel H. Giles, Marius Ueffing, Robert B. Russell, Ronald Roepman, UK10K Rare Diseases Group
Nat Commun. 2016; 7: 11491. Published online 2016 May 13. doi: 10.1038/ncomms11491
PMCID:
PMC4869170
AbstractArticlePDF–2.0M
10.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
11.
A high-throughput approach for measuring temporal changes in the interactome
Anders R. Kristensen, Joerg Gsponer, Leonard J. Foster
Nat Methods. Author manuscript; available in PMC 2014 Mar 14.
Published in final edited form as: Nat Methods. 2012 Sep; 9(9): 907–909. Published online 2012 Aug 5. doi: 10.1038/nmeth.2131
PMCID:
PMC3954081
AbstractArticlePDF–632K
12.
The SUMO1-E67 Interacting Loop Peptide Is an Allosteric Inhibitor of the Dipeptidyl Peptidases 8 and 9
Esther Pilla, Markus Kilisch, Christof Lenz, Henning Urlaub, Ruth Geiss-Friedlander
J Biol Chem. 2013 Nov 8; 288(45): 32787–32796. Published online 2013 Sep 26. doi: 10.1074/jbc.M113.489179
PMCID:
PMC3820912
AbstractArticlePDF–2.7M
13.
Human CIA2A (FAM96A) and CIA2B (FAM96B) integrate maturation of different subsets of cytosolic-nuclear iron-sulfur proteins and iron homeostasis
Oliver Stehling, Judita Mascarenhas, Ajay A. Vashisht, Alex D. Sheftel, Brigitte Niggemeyer, Ralf Rösser, Antonio J. Pierik, James A. Wohlschlegel, Roland Lill
Cell Metab. Author manuscript; available in PMC 2014 Aug 6.
Published in final edited form as: Cell Metab. 2013 Aug 6; 18(2): 187–198. Published online 2013 Jul 25. doi: 10.1016/j.cmet.2013.06.015
Correction in:
Cell Metab. 2018 Jan 9; 27(1): 263.
PMCID:
PMC3784990
AbstractArticlePDF–3.8M
14.
Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver
Sumaiya Chowdhury, Yiqian Chen, Tsun-Wen Yao, Katerina Ajami, Xin M Wang, Yury Popov, Detlef Schuppan, Patrick Bertolino, Geoffrey W McCaughan, Denise MT Yu, Mark D Gorrell
World J Gastroenterol. 2013 May 21; 19(19): 2883–2893. Published online 2013 May 21. doi: 10.3748/wjg.v19.i19.2883
PMCID:
PMC3660813
AbstractArticlePDF–1.2M
15.
Identifying Natural Substrates for Dipeptidyl Peptidases 8 and 9 Using Terminal Amine Isotopic Labeling of Substrates (TAILS) Reveals in Vivo Roles in Cellular Homeostasis and Energy Metabolism
Claire H. Wilson, Dono Indarto, Alain Doucet, Lisa D. Pogson, Melissa R. Pitman, Kym McNicholas, R. Ian Menz, Christopher M. Overall, Catherine A. Abbott
J Biol Chem. 2013 May 17; 288(20): 13936–13949. Published online 2013 Mar 21. doi: 10.1074/jbc.M112.445841
PMCID:
PMC3656252
AbstractArticlePDF–7.0M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
The In Vivo Expression of Dipeptidyl Peptidases 8 and 9
Denise M.T. Yu, Katerina Ajami, Margaret G. Gall, Joohong Park, C. Soon Lee, Kathryn A. Evans, Eileen A. McLaughlin, Melissa R. Pitman, Catherine A. Abbott, Geoffrey W. McCaughan, Mark D. Gorrell
J Histochem Cytochem. 2009 Nov; 57(11): 1025–1040. doi: 10.1369/jhc.2009.953760
PMCID:
PMC2762882
AbstractArticlePDF–3.4M
18.
Ubiquitin-mediated proteolysis of HuR by heat shock
Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe
EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67
PMCID:
PMC2683047
AbstractArticlePDF–1.4M
19.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
20.
Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases.
Shu Y Qi, Pierre J Riviere, Jerzy Trojnar, Jean-Louis Junien, Karen O Akinsanya
Biochem J. 2003 Jul 1; 373(Pt 1): 179–189. doi: 10.1042/BJ20021914
PMCID:
PMC1223468
SummaryPDF–355K

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