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Select item 111591221.

Diagnostic potential in bladder cancer of a panel of tumor markers (calreticulin, γ‐synuclein, and catechol‐o‐methyltransferase) identified by proteomic analysis

Hideaki Iwaki, Susumu Kageyama, Takahiro Isono, Yoshihiko Wakabayashi, Yusaku Okada, Koji Yoshimura, Akito Terai, Yoichi Aral, Hiroshi Iwamura, Mutsushi Kawakita, Tatsuhiro Yoshiki

Cancer Sci. 2004 Dec; 95(12): 955–961. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2004.tb03183.x

PMCID:: PMC11159122

Abstract Article PDF–396K

Select item 111580152.

Aberrant expression and demethylation of γ‐synuclein in colorectal cancer, correlated with progression of the disease

Qing Ye, Min‐Hua Zheng, Qu Cai, Bo Feng, Xue‐Hua Chen, Bei‐Qin Yu, Ya‐Bo Gao, Jun Ji, Ai‐Guo Lu, Jian‐Wen Li, Ming‐Liang Wang, Bing‐Ya Liu

Cancer Sci. 2008 Oct; 99(10): 1924–1932. Published online 2008 Oct 3. doi: 10.1111/j.1349-7006.2008.00947.x

PMCID:: PMC11158015

Abstract Article PDF–473K

Select item 99786353.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 92792854.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91349035.

Gamma synuclein promotes cancer metastasis through the MKK3/6-p38MAPK cascade

Jieya Liu, Ting Shao, Jin Zhang, Qianyi Liu, Hui Hua, Hongying Zhang, Jiao Wang, Ting Luo, Yuenian Eric Shi, Yangfu Jiang

Int J Biol Sci. 2022; 18(8): 3167–3177. Published online 2022 May 1. doi: 10.7150/ijbs.69155

PMCID:: PMC9134903

Abstract Article PDF–3.1M

Select item 90102116.

Upregulation of Synuclein-γ and Snai1 Contributes to Poor Clinical Prognosis in Oral Squamous Cell Carcinoma Patients

Jie Yang, Yangyang Pan, Lu Peng, Licui Zhang, Juan Zhao, Zhihong Zheng, Jun Zheng, Xiaoli Xu, Yan Zeng

Biomed Res Int. 2022; 2022: 6534626. Published online 2022 Apr 7. doi: 10.1155/2022/6534626

PMCID:: PMC9010211

Abstract Article PDF–2.3M

Select item 88570497.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 88118118.

A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG

Ruth Rodríguez‐Barrueco, Jessica Latorre, Laura Devis‐Jáuregui, Aina Lluch, Nuria Bonifaci, Francisco J. Llobet, Mireia Olivan, Laura Coll‐Iglesias, Katja Gassner, Meredith L. Davis, José M. Moreno‐Navarrete, Anna Castells‐Nobau, Laura Plata‐Peña, Miki Dalmau‐Pastor, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, Maria Arnoriaga‐Rodríguez, Wifredo Ricart, José M. Fernández‐Real, José M. Silva, Francisco J. Ortega, David Llobet‐Navas

Adv Sci (Weinh) 2022 Feb; 9(4): 2104759. Published online 2021 Dec 13. doi: 10.1002/advs.202104759

PMCID:: PMC8811811

Abstract Article PDF–6.2M

Select item 83661019.

Gamma‐synuclein is a novel prognostic marker that promotes tumor cell migration in biliary tract carcinoma

Yusuke Takemura, Hidenori Ojima, Go Oshima, Masahiro Shinoda, Yasushi Hasegawa, Minoru Kitago, Hiroshi Yagi, Yuta Abe, Shutaro Hori, Yoko Fujii‐Nishimura, Naoto Kubota, Yuki Masuda, Taizo Hibi, Michiie Sakamoto, Yuko Kitagawa

Cancer Med. 2021 Aug; 10(16): 5599–5613. Published online 2021 Jul 9. doi: 10.1002/cam4.4121

PMCID:: PMC8366101

Abstract Article PDF–2.3M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 704110511.

Curcumin induces re-expression of BRCA1 and suppression of γ synuclein by modulating DNA promoter methylation in breast cancer cell lines

Nujoud Al-Yousef, Zakia Shinwari, Bushra Al-Shahrani, Maram Al-Showimi, Nisreen Al-Moghrabi

Oncol Rep. 2020 Mar; 43(3): 827–838. Published online 2020 Jan 20. doi: 10.3892/or.2020.7473

PMCID:: PMC7041105

Abstract Article PDF–1.1M

Select item 679288912.

Persyn, a Member of the Synuclein Family, Has a Distinct Pattern of Expression in the Developing Nervous System

Vladimir L. Buchman, Hamish J. A. Hunter, Luzia G. P. Pinõn, Jane Thompson, Eugenia M. Privalova, Natalia N. Ninkina, Alun M. Davies

J Neurosci. 1998 Nov 15; 18(22): 9335–9341. doi: 10.1523/JNEUROSCI.18-22-09335.1998

PMCID:: PMC6792889

Abstract Article PDF–630K

Select item 671347513.

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance

Matthew F Pech, Linda E Fong, Jacqueline E Villalta, Leanne JG Chan, Samir Kharbanda, Jonathon J O'Brien, Fiona E McAllister, Ari J Firestone, Calvin H Jan, Jeffrey Settleman

eLife. 2019; 8: e47362. Published online 2019 Aug 27. doi: 10.7554/eLife.47362

PMCID:: PMC6713475

Abstract Article PDF–4.6M

Select item 661788814.

Silencing of Synuclein-γ inhibits human cervical cancer through the AKT signaling pathway

Chunnian Zhang, Liqin Gu, Xiafang Li, Jianzhong Wang

Cell Mol Biol Lett. 2019; 24: 49. Published online 2019 Jul 10. doi: 10.1186/s11658-019-0172-y

PMCID:: PMC6617888

Abstract Article PDF–1.5M

Select item 631976115.

Suppression, disaggregation, and modulation of γ‐Synuclein fibrillation pathway by green tea polyphenol EGCG

Sneha Roy, Rajiv Bhat

Protein Sci. 2019 Feb; 28(2): 382–402. Published online 2018 Dec 20. doi: 10.1002/pro.3549

PMCID:: PMC6319761

Abstract Article PDF–10M

Select item 600317616.

Extracellular gamma-synuclein promotes tumor cell motility by activating β1 integrin-focal adhesion kinase signaling pathway and increasing matrix metalloproteinase-24, -2 protein secretion

Caiyun Liu, Like Qu, Chuanke Zhao, Chengchao Shou

J Exp Clin Cancer Res. 2018; 37: 117. Published online 2018 Jun 15. doi: 10.1186/s13046-018-0783-6

PMCID:: PMC6003176

Abstract Article PDF–6.0M

Select item 596733817.

Gamma synuclein is a novel Twist1 target that promotes TGF-β-induced cancer cell migration and invasion

Ting Shao, Peiying Song, Hui Hua, Hongying Zhang, Xiangmin Sun, Qingbin Kong, Jiao Wang, Ting Luo, Yangfu Jiang

Cell Death Dis. 2018 Jun; 9(6): 625. Published online 2018 May 24. doi: 10.1038/s41419-018-0657-z

PMCID:: PMC5967338

Abstract Article PDF–2.3M

Select item 536051218.

Synuclein-γ (SNCG) in Uterine Serous Carcinoma Impacts Survival: An NRG Oncology/ Gynecologic Oncology Group study

Abigail D. Winder, Kruti P. Maniar, Jian-Jun Wei, Dachao Liu, Denise M. Scholtens, John R. Lurain, Julian C. Schink, Barbara Buttin, Virginia L. Filiaci, Heather A. Lankes, Nilsa C. Ramirez, Kay Park, Meenakshi Singh, Richard W. Lieberman, Robert S. Mannel, Matthew A. Powell, Floor J. Backes, Cara A. Mathews, Michael L. Pearl, Angeles Alvarez Secord, David J. Peace, David G. Mutch, William T. Creasman, J. Julie Kim

Cancer. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Cancer. 2017 Apr 1; 123(7): 1144–1155. Published online 2016 Dec 7. doi: 10.1002/cncr.30477

PMCID:: PMC5360512

Abstract Article PDF–1.4M

Select item 535474419.

Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of Υ-synuclein in hepatocellular carcinoma cells

Xiaoqin He, Yongfa Zheng, Yuefeng Zhang, Yuanyuan Gan, Yujie Zhou, Huilin Liang, Dongcheng Wu, Wei Ge, Junjian Deng, Ximing Xu

Oncotarget. 2017 Feb 7; 8(6): 9451–9465. Published online 2016 Dec 27. doi: 10.18632/oncotarget.14276

PMCID:: PMC5354744

Abstract Article PDF–13M

Select item 519003520.

Urine gamma-synuclein as a biomarker for the diagnosis of bladder cancer

Caiyun Liu, Bingbing Shi, Chonghua Hao, Qinghai Wang, Qiang Lv, Nianzeng Xing, Jianzhong Shou, Like Qu, Yanning Gao, Chao Qin, Jiyu Zhao, Chengchao Shou

Oncotarget. 2016 Jul 12; 7(28): 43432–43441. Published online 2016 May 19. doi: 10.18632/oncotarget.9468

PMCID:: PMC5190035

Abstract Article PDF–3.4M

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