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Items: 15

1.
Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism
Maroof Hasan, Vijay K. Gonugunta, Nicole Dobbs, Aktar Ali, Guillermo Palchik, Maria A. Calvaruso, Ralph J. DeBerardinis, Nan Yan
Proc Natl Acad Sci U S A. 2017 Jan 24; 114(4): 746–751. Published online 2017 Jan 9. doi: 10.1073/pnas.1611113114
PMCID:
PMC5278463
AbstractArticlePDF–1.3M
2.
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
Daxing Gao, Tuo Li, Xiao-Dong Li, Xiang Chen, Quan-Zhen Li, Mary Wight-Carter, Zhijian J. Chen
Proc Natl Acad Sci U S A. 2015 Oct 20; 112(42): E5699–E5705. Published online 2015 Sep 14. doi: 10.1073/pnas.1516465112
PMCID:
PMC4620884
AbstractArticlePDF–1.2M
3.
Cytosolic nuclease TREX1 regulates oligosaccharyltransferase activity independent of nuclease activity to suppress immune activation
Maroof Hasan, Charles S. Fermaintt, Ningguo Gao, Tomomi Sakai, Takuya Miyazaki, Sixin Jiang, Quan-Zhen Li, John P. Atkinson, Herbert C. Morse, III, Mark A. Lehrman, Nan Yan
Immunity. Author manuscript; available in PMC 2016 Sep 15.
Published in final edited form as: Immunity. 2015 Sep 15; 43(3): 463–474. Published online 2015 Aug 25. doi: 10.1016/j.immuni.2015.07.022
PMCID:
PMC4575271
AbstractArticlePDF–2.0M
4.
Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease
Jessica L. Grieves, Jason M. Fye, Scott Harvey, Jason M. Grayson, Thomas Hollis, Fred W. Perrino
Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16): 5117–5122. Published online 2015 Apr 6. doi: 10.1073/pnas.1423804112
PMCID:
PMC4413332
AbstractArticlePDF–1.3M
5.
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
Martin R. Jakobsen, Rasmus O. Bak, Annika Andersen, Randi K. Berg, Søren B. Jensen, Tengchuan Jin, Anders Laustsen, Kathrine Hansen, Lars Østergaard, Katherine A. Fitzgerald, T. Sam Xiao, Jacob G. Mikkelsen, Trine H. Mogensen, Søren R. Paludan
Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48): E4571–E4580. Published online 2013 Oct 23. doi: 10.1073/pnas.1311669110
Correction in:
Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48): 19651.
PMCID:
PMC3845190
AbstractArticlePDF–1.6M
6.
Filamin-A Regulates Neutrophil Uropod Retraction through RhoA during Chemotaxis
Chunxiang Sun, Carol Forster, Fumihiko Nakamura, Michael Glogauer
PLoS One. 2013; 8(10): e79009. Published online 2013 Oct 25. doi: 10.1371/journal.pone.0079009
PMCID:
PMC3808352
AbstractArticlePDF–724K
7.
Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes
Maroof Hasan, James Koch, Dinesh Rakheja, Asit K. Pattnaik, James Brugarolas, Igor Dozmorov, Beth Levine, Edward K. Wakeland, Min Ae Lee-kirsch, Nan Yan
Nat Immunol. Author manuscript; available in PMC 2013 Jul 1.
Published in final edited form as: Nat Immunol. 2013 Jan; 14(1): 61–71. Published online 2012 Nov 18. doi: 10.1038/ni.2475
PMCID:
PMC3522772
AbstractArticlePDF–1.5M
8.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
9.
Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage
Markus Christmann, Maja T. Tomicic, Dorthe Aasland, Nicole Berdelle, Bernd Kaina
Nucleic Acids Res. 2010 Oct; 38(19): 6418–6432. Published online 2010 May 28. doi: 10.1093/nar/gkq455
PMCID:
PMC2965218
AbstractArticlePDF–1.3M
10.
The cytosolic exonuclease TREX1 inhibits the innate immune response to HIV-1
Nan Yan, Ashton D. Regalado-Magdos, Bart Stiggelbout, Min Ae Lee-Kirsch, Judy Lieberman
Nat Immunol. Author manuscript; available in PMC 2011 May 1.
Published in final edited form as: Nat Immunol. 2010 Nov; 11(11): 1005–1013. Published online 2010 Sep 26. doi: 10.1038/ni.1941
PMCID:
PMC2958248
AbstractArticlePDF–1.6M
11.
Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir
Gabriele B. Beck-Engeser, Dan Eilat, Thomas Harrer, Hans-Martin Jäck, Matthias Wabl
Proc Natl Acad Sci U S A. 2009 Dec 8; 106(49): 20865–20870. Published online 2009 Nov 18. doi: 10.1073/pnas.0908074106
PMCID:
PMC2791572
AbstractArticlePDF–1.7M
12.
Trex1 prevents cell-intrinsic initiation of autoimmunity
Daniel B. Stetson, Joan S. Ko, Thierry Heidmann, Ruslan Medzhitov
Cell. Author manuscript; available in PMC 2009 Feb 22.
Published in final edited form as: Cell. 2008 Aug 22; 134(4): 587–598. doi: 10.1016/j.cell.2008.06.032
PMCID:
PMC2626626
AbstractArticlePDF–3.0M
13.
ATR Kinase Activation Mediated by MutSα and MutLα in Response to Cytotoxic O6-Methylguanine Adducts
Ken-ichi Yoshioka, Yoshiko Yoshioka, Peggy Hsieh
Mol Cell. Author manuscript; available in PMC 2008 Jun 10.
Published in final edited form as: Mol Cell. 2006 May 19; 22(4): 501–510. doi: 10.1016/j.molcel.2006.04.023
PMCID:
PMC2423943
AbstractArticlePDF–704K
14.
Gene-Targeted Mice Lacking the Trex1 (DNase III) 3′→5′ DNA Exonuclease Develop Inflammatory Myocarditis
Masashi Morita, Gordon Stamp, Peter Robins, Anna Dulic, Ian Rosewell, Geza Hrivnak, Graham Daly, Tomas Lindahl, Deborah E. Barnes
Mol Cell Biol. 2004 Aug; 24(15): 6719–6727. doi: 10.1128/MCB.24.15.6719-6727.2004
PMCID:
PMC444847
AbstractArticlePDF–661K
15.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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