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Select item 91714111.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 88970222.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 88666133.

Bi-allelic variants in DNAH10 cause asthenoteratozoospermia and male infertility

Kuokuo Li, Guanxiong Wang, Mingrong Lv, Jieyu Wang, Yang Gao, Fei Tang, Chuan Xu, Wen Yang, Hui Yu, Zhongmei Shao, Hao Geng, Qing Tan, Qunshan Shen, Dongdong Tang, Xiaoqing Ni, Tianjuan Wang, Bing Song, Huan Wu, Ran Huo, Zhiguo Zhang, Yuping Xu, Ping Zhou, Fangbiao Tao, Zhaolian Wei, Xiaojin He, Yunxia Cao

J Assist Reprod Genet. 2022 Jan; 39(1): 251–259. Published online 2021 Oct 16. doi: 10.1007/s10815-021-02306-x

PMCID:: PMC8866613

Abstract Article PDF–2.2M

Select item 88288954.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 85529075.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 83874676.

Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice

Chaofeng Tu, Jiangshan Cong, Qianjun Zhang, Xiaojin He, Rui Zheng, Xiaoxuan Yang, Yang Gao, Huan Wu, Mingrong Lv, Yayun Gu, Shuai Lu, Chunyu Liu, Shixiong Tian, Lanlan Meng, Weili Wang, Chen Tan, Hongchuan Nie, Dongyan Li, Huan Zhang, Fei Gong, Liang Hu, Guangxiu Lu, Wenming Xu, Ge Lin, Feng Zhang, Yunxia Cao, Yue-Qiu Tan

Am J Hum Genet. 2021 Aug 5; 108(8): 1466–1477. Published online 2021 Jul 7. doi: 10.1016/j.ajhg.2021.06.010

PMCID:: PMC8387467

Abstract Article PDF–2.5M

Select item 83641817.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 71385378.

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism

Johanna Hietamäki, Louise C Gregory, Sandy Ayoub, Anna-Pauliina Iivonen, Kirsi Vaaralahti, Xiaonan Liu, Nina Brandstack, Andrew J Buckton, Tiina Laine, Johanna Känsäkoski, Matti Hero, Päivi J Miettinen, Markku Varjosalo, Emma Wakeling, Mehul T Dattani, Taneli Raivio

J Clin Endocrinol Metab. 2020 Jun; 105(6): 1748–1758. Published online 2020 Feb 15. doi: 10.1210/clinem/dgaa078

PMCID:: PMC7138537

Abstract Article

Select item 70535929.

DNAH10 mutation correlates with cisplatin sensitivity and tumor mutation burden in small-cell lung cancer

Man Li, Anqi Lin, Peng Luo, Weitao Shen, Dan Xiao, Lanying Gou, Jian Zhang, Linlang Guo

Aging (Albany NY) 2020 Jan 31; 12(2): 1285–1303. Published online 2020 Jan 20. doi: 10.18632/aging.102683

PMCID:: PMC7053592

Abstract Article PDF–5.2M

Select item 691099810.

Discovery of increased epidermal DNAH10 expression after regeneration of dermis in a randomized with-in person trial — reflections on psoriatic inflammation

Heli Lagus, Mariliis Klaas, Susanna Juteau, Outi Elomaa, Juha Kere, Jyrki Vuola, Viljar Jaks, Esko Kankuri

Sci Rep. 2019; 9: 19136. Published online 2019 Dec 13. doi: 10.1038/s41598-019-53874-z

PMCID:: PMC6910998

Abstract Article PDF–3.6M

Select item 689109711.

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

Divya Achuthankutty, Roshan Singh Thakur, Peter Haahr, Saskia Hoffmann, Alexandros P. Drainas, Anna H. Bizard, Joachim Weischenfeldt, Ian D. Hickson, Niels Mailand

J Cell Biol. 2019 Dec 2; 218(12): 3943–3953. Published online 2019 Oct 15. doi: 10.1083/jcb.201905064

PMCID:: PMC6891097

Abstract Article PDF–2.7M

Select item 677813712.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 658119713.

Gain of additional BIRC3 protein functions through 3′UTR-mediated protein complex formation

Shih-Han Lee, Christine Mayr

Mol Cell. Author manuscript; available in PMC 2020 May 16.

Published in final edited form as: Mol Cell. 2019 May 16; 74(4): 701–712.e9. Published online 2019 Apr 1. doi: 10.1016/j.molcel.2019.03.006

PMCID:: PMC6581197

Abstract Article PDF–2.0M

Select item 646186414.

LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition

Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hsiao, Tina K. Nguyen, Peter K. Park, Sergey D. Egranov, David H. Hawke, Jeffrey R. Marks, Leng Han, Mien-Chie Hung, Bing Zhang, Chunru Lin, Liuqing Yang

Cell Res. 2019 Apr; 29(4): 286–304. Published online 2019 Jan 10. doi: 10.1038/s41422-018-0134-3

PMCID:: PMC6461864

Abstract Article PDF–11M

Select item 644186815.

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

Boshi Wang, Xiaoli Xu, Zhaojuan Yang, Li Zhang, Yun Liu, Aihui Ma, Guiqin Xu, Ming Tang, Tiantian Jing, Lin Wu, Yongzhong Liu

EBioMedicine. 2019 Mar; 41: 320–332. Published online 2019 Feb 7. doi: 10.1016/j.ebiom.2019.01.058

PMCID:: PMC6441868

Abstract Article PDF–7.0M

Select item 616668216.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 586483217.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 577458418.

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

Luca A. Lotta, Pawan Gulati, Felix R. Day, Felicity Payne, Halit Ongen, Martijn van de Bunt, Kyle J. Gaulton, John D. Eicher, Stephen J. Sharp, Jian’an Luan, Emanuella De Lucia Rolfe, Isobel D. Stewart, Eleanor Wheeler, Sara M. Willems, Claire Adams, Hanieh Yaghootkar, EPIC-InterAct Consortium, Cambridge FPLD1 Consortium, Nita G. Forouhi, Kay-Tee Khaw, Andrew D. Johnson, Robert K. Semple, Timothy Frayling, John R. B. Perry, Emmanouil Dermitzakis, Mark I. McCarthy, Inês Barroso, Nicholas J. Wareham, David B. Savage, Claudia Langenberg, Stephen O’Rahilly, Robert A. Scott

Nat Genet. Author manuscript; available in PMC 2018 Jan 19.

Published in final edited form as: Nat Genet. 2017 Jan; 49(1): 17–26. Published online 2016 Nov 14. doi: 10.1038/ng.3714

PMCID:: PMC5774584

Abstract Article PDF–1.5M

Select item 505735819.

Variants in the genes DCTN2,DNAH10,LRIG3, and MYO1A are associated with intermediate Charcot–Marie–Tooth disease in a Norwegian family

G. J. Braathen, H. Høyer, Ø. L. Busk, K. Tveten, C. F. Skjelbred, M. B. Russell

Acta Neurol Scand. 2016 Jul; 134(1): 67–75. Published online 2015 Oct 12. doi: 10.1111/ane.12515

PMCID:: PMC5057358

Abstract Article PDF–385K

Select item 460415520.

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy

Bethany L. Johnson-Kerner, Alejandro Garcia Diaz, Sean Ekins, Hynek Wichterle

PLoS One. 2015; 10(10): e0140157. Published online 2015 Oct 13. doi: 10.1371/journal.pone.0140157

PMCID:: PMC4604155

Abstract Article PDF–2.9M

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