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Select item 92626141.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76810343.

Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components

Chuan-Jin Wu, Xing Li, Connie L. Sommers, Kiyoto Kurima, Sunmee Huh, Grace Bugos, Lijin Dong, Wenmei Li, Andrew J. Griffith, Lawrence E. Samelson

J Biol Chem. 2020 Nov 20; 295(47): 16086–16099. Published online 2020 Sep 11. doi: 10.1074/jbc.RA120.013045

PMCID:: PMC7681034

Abstract Article PDF–1.8M

Select item 73220674.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 65364096.

Suppression of long non‐coding RNA TNRC6C‐AS1 protects against thyroid carcinoma through DNA demethylation of STK4 via the Hippo signalling pathway

Liu‐Xue Yang, Ji Wu, Man‐Li Guo, Yong Zhang, Shao‐Gang Ma

Cell Prolif. 2019 May; 52(3): e12564. Published online 2019 Apr 1. doi: 10.1111/cpr.12564

PMCID:: PMC6536409

Abstract Article PDF–1.6M

Select item 64632137.

The long noncoding RNA ROCKI regulates inflammatory gene expression

Qiong Zhang, Ti‐Chun Chao, Veena S Patil, Yue Qin, Shashi Kant Tiwari, Joshua Chiou, Alexander Dobin, Chih‐Ming Tsai, Zhonghan Li, Jason Dang, Shagun Gupta, Kevin Urdahl, Victor Nizet, Thomas R Gingeras, Kyle J Gaulton, Tariq M Rana

EMBO J. 2019 Apr 15; 38(8): e100041. Published online 2019 Mar 27. doi: 10.15252/embj.2018100041

PMCID:: PMC6463213

Abstract Article PDF–2.6M

Select item 61666828.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 61229649.

The human CIB1–EVER1–EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses

Sarah Jill de Jong, Amandine Créquer, Irina Matos, David Hum, Vignesh Gunasekharan, Lazaro Lorenzo, Fabienne Jabot-Hanin, Elias Imahorn, Andres A. Arias, Hassan Vahidnezhad, Leila Youssefian, Janet G. Markle, Etienne Patin, Aurelia D’Amico, Claire Q.F. Wang, Florian Full, Armin Ensser, Tina M. Leisner, Leslie V. Parise, Matthieu Bouaziz, Nataly Portilla Maya, Xavier Rueda Cadena, Bayaki Saka, Amir Hossein Saeidian, Nessa Aghazadeh, Sirous Zeinali, Peter Itin, James G. Krueger, Lou Laimins, Laurent Abel, Elaine Fuchs, Jouni Uitto, Jose Luis Franco, Bettina Burger, Gérard Orth, Emmanuelle Jouanguy, Jean-Laurent Casanova

J Exp Med. 2018 Sep 3; 215(9): 2289–2310. doi: 10.1084/jem.20170308

PMCID:: PMC6122964

Abstract Article PDF–2.4M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549522511.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 537173012.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 512919913.

Genetic polymorphisms of FAS and EVER genes in a Greek population and their susceptibility to cervical cancer: a case control study

Evangelia Pavlidou, Alexandros Daponte, Raquel Egea, Efthimios Dardiotis, Georgios M. Hadjigeorgiou, Antonio Barbadilla, Theodoros Agorastos

BMC Cancer. 2016; 16: 923. Published online 2016 Nov 29. doi: 10.1186/s12885-016-2960-3

PMCID:: PMC5129199

Abstract Article PDF–406K

Select item 469525914.

Genetic variations of the EVER genes, cutaneous human papillomavirus (HPV) infection, and squamous cell carcinoma of the skin

S.S. Hampras, D.E. Rollison, M. Tommasino, T. Gheit, M.B. Schabath, J.L. Messina, N.A. Fenske, B.S. Cherpelis, V.K. Sondak, M.R. Iannacone, M. Schmitt, M. Pawlita

Br J Dermatol. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Br J Dermatol. 2015 Dec; 173(6): 1532–1535. Published online 2015 Nov 2. doi: 10.1111/bjd.13991

PMCID:: PMC4695259

Article PDF–211K

Select item 445788315.

Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

Mary J. Emond, Tin Louie, Julia Emerson, Jessica X. Chong, Rasika A. Mathias, Michael R. Knowles, Mark J. Rieder, Holly K. Tabor, Debbie A. Nickerson, Kathleen C. Barnes, NHLBI GO Exome Sequencing Project, Lung GO, Ronald L. Gibson, Michael J. Bamshad

PLoS Genet. 2015 Jun; 11(6): e1005273. Published online 2015 Jun 5. doi: 10.1371/journal.pgen.1005273

Correction in:: PLoS Genet. 2015 Aug; 11(8): e1005424.

PMCID:: PMC4457883

Abstract Article PDF–1.6M

Select item 430065816.

Expression of the Epidermodysplasia Verruciformis-Associated Genes EVER1 and EVER2 Is Activated by Exogenous DNA and Inhibited by LMP1 Oncoprotein from Epstein-Barr Virus

Cecilia Frecha, Sébastien A. Chevalier, Patrick van Uden, Ivonne Rubio, Maha Siouda, Djamel Saidj, Camille Cohen, Patrick Lomonte, Rosita Accardi, Massimo Tommasino

J Virol. 2015 Jan 15; 89(2): 1461–1467. Published online 2014 Nov 5. doi: 10.1128/JVI.02936-14

PMCID:: PMC4300658

Abstract Article PDF–1.2M

Select item 408237217.

The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease

Stefanie L. Butland, Shaun S. Sanders, Mandi E. Schmidt, Sean-Patrick Riechers, David T.S. Lin, Dale D.O. Martin, Kuljeet Vaid, Rona K. Graham, Roshni R. Singaraja, Erich E. Wanker, Elizabeth Conibear, Michael R. Hayden

Hum Mol Genet. 2014 Aug 1; 23(15): 4142–4160. Published online 2014 Apr 4. doi: 10.1093/hmg/ddu137

PMCID:: PMC4082372

Abstract Article PDF–1.7M

Select item 381232418.

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans

J L Del-Aguila, A L Beitelshees, R M Cooper-DeHoff, A B Chapman, J G Gums, K Bailey, Y Gong, S T Turner, J A Johnson, E Boerwinkle

Pharmacogenomics J. 2014 Feb; 14(1): 35–40. Published online 2013 Feb 12. doi: 10.1038/tpj.2013.3

PMCID:: PMC3812324

Abstract Article PDF–662K

Select item 353061319.

Contribution of TMC6 and 8 (EVER1 and2) variants to cervical cancer susceptibility

Felipe A. Castro, Emma L. Ivansson, Markus Schmitt, Ivana Juko-Pecirep, Lennart Kjellberg, Allan Hildesheim, Ulf B. Gyllensten, Michael Pawlita

Int J Cancer. Author manuscript; available in PMC 2012 Dec 26.

Published in final edited form as: Int J Cancer. 2012 Jan 15; 130(2): 349–355. Published online 2011 May 5. doi: 10.1002/ijc.26016

PMCID:: PMC3530613

Abstract Article PDF–627K

Select item 339846620.

Autosomal dominant epidermodysplasia verruciformis lacking a known EVER1 or EVER2 mutation

David H. McDermott, Bryan Gammon, Peter J. Snijders, Ihunanya Mbata, Beth Phifer, A. Howland Hartley, Chyi-Chia Richard Lee, Philip M. Murphy, Sam T. Hwang

Pediatr Dermatol. Author manuscript; available in PMC 2012 Jul 17.

Published in final edited form as: Pediatr Dermatol. 2009 May-Jun; 26(3): 306–310. doi: 10.1111/j.1525-1470.2008.00853.x

PMCID:: PMC3398466

Abstract Article PDF–669K

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