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Items: 1 to 20 of 79

1.
SIRT5 promote malignant advancement of chordoma by regulating the desuccinylation of c-myc
Minghui Jiang, Zheng Huang, Li Chen, Ting Deng, Junpeng Liu, Yue Wu
BMC Cancer. 2024; 24: 386. Published online 2024 Mar 26. doi: 10.1186/s12885-024-12140-w
PMCID:
PMC10967166
AbstractArticlePDF–7.8M
2.
LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer
Oh Kwang Kwon, In Hyuk Bang, So Young Choi, Ju Mi Jeon, Ann-Yae Na, Yan Gao, Sam Seok Cho, Sung Hwan Ki, Youngshik Choe, Jun Nyung Lee, Yun-Sok Ha, Eun Ju Bae, Tae Gyun Kwon, Byung-Hyun Park, Sangkyu Lee
Genomics Proteomics Bioinformatics. 2023 Feb; 21(1): 177–189. Published online 2022 Mar 9. doi: 10.1016/j.gpb.2022.02.004
PMCID:
PMC10372916
AbstractArticlePDF–2.4M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Cells. 2023 Mar; 12(6): 852. Published online 2023 Mar 9. doi: 10.3390/cells12060852
PMCID:
PMC10047932
AbstractArticlePDF–3.8M
5.
The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease
Judy Baek, Kelli Sas, Chenchen He, Viji Nair, William Giblin, Ayaka Inoki, Hongyu Zhang, Yang Yingbao, Jeffrey Hodgin, Robert G. Nelson, Frank C. Brosius, III, Matthias Kretzler, Paul M. Stemmer, David B. Lombard, Subramaniam Pennathur
J Biol Chem. 2023 Mar; 299(3): 102960. Published online 2023 Feb 2. doi: 10.1016/j.jbc.2023.102960
PMCID:
PMC9996370
AbstractArticlePDF–2.7M
6.
Circ-ATL1 silencing reverses the activation effects of SIRT5 on smooth muscle cellular proliferation, migration and contractility in intracranial aneurysm by adsorbing miR-455
Jichong Xu, Chun Fang
BMC Mol Cell Biol. 2023; 24: 3. Published online 2023 Jan 30. doi: 10.1186/s12860-022-00461-2
PMCID:
PMC9887762
AbstractArticlePDF–4.3M
7.
Sirtuin5 protects colorectal cancer from DNA damage by keeping nucleotide availability
Hao-Lian Wang, Yan Chen, Yun-Qian Wang, En-Wei Tao, Juan Tan, Qian-Qian Liu, Chun-Min Li, Xue-Mei Tong, Qin-Yan Gao, Jie Hong, Ying-Xuan Chen, Jing-Yuan Fang
Nat Commun. 2022; 13: 6121. Published online 2022 Oct 17. doi: 10.1038/s41467-022-33903-8
PMCID:
PMC9576705
AbstractArticlePDF–6.0M
8.
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein
Marius Walter, Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam, Jennifer M. Hayashi, Andrew Cruz, Samah Shah, Frank W. Soveg, John D. Gross, Nevan J. Krogan, Keith R. Jerome, Birgit Schilling, Melanie Ott, Eric Verdin
PLoS Pathog. 2022 Sep; 18(9): e1010811. Published online 2022 Sep 12. doi: 10.1371/journal.ppat.1010811
PMCID:
PMC9499238
AbstractArticlePDF–3.7M
9.
Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis
Pengbo Yao, Taiqi Chen, Peng Jiang, Li Li, Wenjing Du
EMBO Rep. 2022 Sep; 23(9): e54391. Published online 2022 Jun 30. doi: 10.15252/embr.202154391
PMCID:
PMC9442300
AbstractArticlePDF–5.2M
10.
The global succinylation of SARS-CoV-2–infected host cells reveals drug targets
Quan Liu, Heming Wang, He Zhang, Liyan Sui, Letian Li, Wang Xu, Shouwen Du, Pengfei Hao, Yuhang Jiang, Jing Chen, Xiaoyun Qu, Mingyao Tian, Yinghua Zhao, Xuerui Guo, Xingye Wang, Wu Song, Guangqi Song, Zhengkai Wei, Zhijun Hou, Guoqing Wang, Minhua Sun, Xiao Li, Huijun Lu, Xinyu Zhuang, Ningyi Jin, Yicheng Zhao, Chang Li, Ming Liao
Proc Natl Acad Sci U S A. 2022 Jul 26; 119(30): e2123065119. Published online 2022 Jul 12. doi: 10.1073/pnas.2123065119
PMCID:
PMC9335334
AbstractArticlePDF–5.0M
11.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
12.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
13.
LINC01234 regulates microRNA-27b-5p to induce the migration, invasion and self-renewal of ovarian cancer stem cells through targeting SIRT5
Fang Ke, Chenchen Ren, Zihan Zhai, Xiang Gao, Jing Wei, Yuanhang Zhu, Yunxiao Zhi
Cell Cycle. 2022; 21(10): 1020–1033. Published online 2022 Mar 1. doi: 10.1080/15384101.2022.2040282
PMCID:
PMC9037434
AbstractArticlePDF–3.6M
14.
SIRT5 Directly Inhibits the PI3K/AKT Pathway in Prostate Cancer Cell Lines
SO YOUNG CHOI, JU MI JEON, ANN YAE NA, OH KWANG KWON, IN HYUK BANG, YUN-SOK HA, EUN JU BAE, BYUNG-HYUN PARK, EUN HYE LEE, TAE GYUN KWON, JUN NYUNG LEE, SANGKYU LEE
Cancer Genomics Proteomics. 2022 Jan-Feb; 19(1): 50–59. Published online 2022 Jan 3. doi: 10.21873/cgp.20303
PMCID:
PMC8717960
AbstractArticlePDF–3.3M
15.
SIRT5 functions as a tumor suppressor in renal cell carcinoma by reversing the Warburg effect
Liu Yihan, Wang Xiaojing, Liu Ao, Zhang Chuanjie, Wang Haofei, Shen Yan, He Hongchao
J Transl Med. 2021; 19: 521. Published online 2021 Dec 20. doi: 10.1186/s12967-021-03178-6
PMCID:
PMC8690424
AbstractArticlePDF–6.0M
16.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
17.
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-induced Pancreatic Cancer Progression
Tuo Hu, Surendra K Shukla, Enza Vernucci, Chunbo He, Dezhen Wang, Ryan J King, Kanupriya Jha, Kasturi Siddhanta, Nicholas J Mullen, Kuldeep S Attri, Divya Murthy, Nina V Chaika, Ravi Thakur, Scott E Mulder, Camila G Pacheco, Xiao Fu, Robin R High, Fang Yu, Audrey Lazenby, Clemens Steegborn, Ping Lan, Kamiya Mehla, Dante Rotili, Sarika Chaudhary, Sergio Valente, Marco Tafani, Antonello Mai, Johan Auwerx, Eric Verdin, David Tuveson, Pankaj K Singh
Gastroenterology. Author manuscript; available in PMC 2022 Nov 1.
Published in final edited form as: Gastroenterology. 2021 Nov; 161(5): 1584–1600. Published online 2021 Jul 8. doi: 10.1053/j.gastro.2021.06.045
PMCID:
PMC8546779
AbstractArticlePDF–3.6M
18.
The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
William Giblin, Lauren Bringman-Rodenbarger, Angela H. Guo, Surinder Kumar, Alexander C. Monovich, Ahmed M. Mostafa, Mary E. Skinner, Michelle Azar, Ahmed S.A. Mady, Carolina H. Chung, Namrata Kadambi, Keith-Allen Melong, Ho-Joon Lee, Li Zhang, Peter Sajjakulnukit, Sophie Trefely, Erika L. Varner, Sowmya Iyer, Min Wang, James S. Wilmott, H. Peter Soyer, Richard A. Sturm, Antonia L. Pritchard, Aleodor A. Andea, Richard A. Scolyer, Mitchell S. Stark, David A. Scott, Douglas R. Fullen, Marcus W. Bosenberg, Sriram Chandrasekaran, Zaneta Nikolovska-Coleska, Monique E. Verhaegen, Nathaniel W. Snyder, Miguel N. Rivera, Andrei L. Osterman, Costas A. Lyssiotis, David B. Lombard
J Clin Invest. 2021 Jun 15; 131(12): e138926. Published online 2021 Jun 15. doi: 10.1172/JCI138926
PMCID:
PMC8203465
AbstractArticlePDF–8.7M
19.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
20.
SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia
Dongqing Yan, Anca Franzini, Anthony D. Pomicter, Brayden J. Halverson, Orlando Antelope, Clinton C. Mason, Jonathan M. Ahmann, Anna V. Senina, Nadeem A. Vellore, Courtney L. Jones, Matthew S. Zabriskie, Hein Than, Michael J. Xiao, Alexandria van Scoyk, Ami B. Patel, Phillip M. Clair, William L. Heaton, Shawn C. Owen, Joshua L. Andersen, Christina M. Egbert, Julie A. Reisz, Angelo D'Alessandro, James E. Cox, Kevin C. Gantz, Hannah M. Redwine, Siddharth M. Iyer, Jamshid S. Khorashad, Nima Rajabi, Christian A. Olsen, Thomas O'Hare, Michael W. Deininger
Blood Cancer Discov. 2021 May; 2(3): 266–287. Published online 2021 Apr 10. doi: 10.1158/2643-3230.BCD-20-0168
PMCID:
PMC8133360
AbstractArticlePDF–14M

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