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Select item 108428521.

SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer

Yuuki Ohara, Wei Tang, Huaitian Liu, Shouhui Yang, Tiffany H. Dorsey, Helen Cawley, Paloma Moreno, Raj Chari, Mary R. Guest, Azadeh Azizian, Jochen Gaedcke, Michael Ghadimi, Nader Hanna, Stefan Ambs, S. Perwez Hussain

Cell Rep. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113434. Published online 2023 Nov 18. doi: 10.1016/j.celrep.2023.113434

PMCID:: PMC10842852

Abstract Article PDF–1.8M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101122813.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

François Le Guerroué, Eric N Bunker, William M Rosencrans, Jack T Nguyen, Mohammed A Basar, Achim Werner, Tsui-Fen Chou, Chunxin Wang, Richard J Youle

Mol Cell. Author manuscript; available in PMC 2024 Mar 16.

Published in final edited form as: Mol Cell. 2023 Mar 16; 83(6): 927–941.e8. Published online 2023 Mar 9. doi: 10.1016/j.molcel.2023.02.023

PMCID:: PMC10112281

Abstract Article PDF–2.4M

Select item 100395114.

Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology

Yanting Su, Yuanyuan Guo, Jieyu Guo, Ting Zeng, Ting Wang, Wu Liu

BMC Genomics. 2023; 24: 146. Published online 2023 Mar 24. doi: 10.1186/s12864-023-09238-z

PMCID:: PMC10039511

Abstract Article PDF–2.0M

Select item 99504475.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 96266886.

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis

Xi Ling, Jiayi Lu, Xiaoyun Wang, Lan Liu, Lu Liu, Yadi Wang, Yujun Sun, Chune Ren, Chao Lu, Zhenhai Yu

iScience. 2022 Nov 18; 25(11): 105363. Published online 2022 Oct 14. doi: 10.1016/j.isci.2022.105363

PMCID:: PMC9626688

Abstract Article PDF–6.0M

Select item 95312997.

Regulation of membrane fluidity by RNF145‐triggered degradation of the lipid hydrolase ADIPOR2

Norbert Volkmar, Christian M Gawden‐Bone, James C Williamson, Jonathon Nixon‐Abell, James A West, Peter H St George‐Hyslop, Arthur Kaser, Paul J Lehner

EMBO J. 2022 Oct; 41(19): e110777. Published online 2022 Aug 22. doi: 10.15252/embj.2022110777

PMCID:: PMC9531299

Abstract Article PDF–6.9M

Select item 93383138.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 93048059.

SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease

Erica Novo, Andrea Cappon, Gianmarco Villano, Santina Quarta, Stefania Cannito, Claudia Bocca, Cristian Turato, Maria Guido, Marina Maggiora, Francesca Protopapa, Salvatore Sutti, Alessia Provera, Mariagrazia Ruvoletto, Alessandra Biasiolo, Beatrice Foglia, Emanuele Albano, Patrizia Pontisso, Maurizio Parola

Front Immunol. 2022; 13: 910526. Published online 2022 Jul 8. doi: 10.3389/fimmu.2022.910526

PMCID:: PMC9304805

Abstract Article PDF–6.9M

Select item 929010410.

The protease‐inhibitor SerpinB3 as a critical modulator of the stem‐like subset in human cholangiocarcinoma

Margherita Correnti, Andrea Cappon, Mirella Pastore, Benedetta Piombanti, Giulia Lori, Douglas V. P. N. Oliveira, Patricia Munoz‐Garrido, Monika Lewinska, Jesper B. Andersen, Cédric Coulouarn, Laurent Sulpice, Caterina Peraldo Neia, Giuliana Cavalloni, Santina Quarta, Alessandra Biasiolo, Matteo Fassan, Matteo Ramazzotti, Matteo Parri, Stefania Recalcati, Luca di Tommaso, Claudia Campani, Pietro Invernizzi, Guido Torzilli, Fabio Marra, Patrizia Pontisso, Chiara Raggi

Liver Int. 2022 Jan; 42(1): 233–248. Published online 2021 Sep 16. doi: 10.1111/liv.15049

PMCID:: PMC9290104

Abstract Article PDF–3.3M

Select item 927785311.

A functional reference map of the RNF8 interactome in cancer

Chuanyang Liu, Jingyu Kuang, Yuxuan Wang, Ting Duan, Lu Min, Chenyu Lu, Tianyi Zhang, Ruifen Chen, Ying Wu, Lingyun Zhu

Biol Direct. 2022; 17: 17. Published online 2022 Jul 13. doi: 10.1186/s13062-022-00331-z

PMCID:: PMC9277853

Abstract Article PDF–5.9M

Select item 911973612.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 895660413.

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity

Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang

Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8

PMCID:: PMC8956604

Abstract Article PDF–3.9M

Select item 893051514.

Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination

Angelo Cirinelli, Justin Wheelan, Christopher Grieg, Carlos A. Molina

Exp Cell Res. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Exp Cell Res. 2022 May 1; 414(1): 113083. Published online 2022 Feb 26. doi: 10.1016/j.yexcr.2022.113083

PMCID:: PMC8930515

Abstract Article PDF–1.9M

Select item 875581415.

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins

Cliff J. Luke, Stephanie Markovina, Misty Good, Ira E. Wight, Brian J. Thomas, John M. Linneman, Wyatt E. Lanik, Olga Koroleva, Maggie R. Coffman, Mark T. Miedel, Qingqing Gong, Arlise Andress, Marlene Campos Guerrero, Songyan Wang, LiYun Chen, Wandy L. Beatty, Kelsey N. Hausmann, Frances V. White, James A. J. Fitzpatrick, Anthony Orvedahl, Stephen C. Pak, Gary A. Silverman

Commun Biol. 2022; 5: 47. Published online 2022 Jan 12. doi: 10.1038/s42003-021-02953-x

PMCID:: PMC8755814

Abstract Article PDF–6.8M

Select item 865603316.

Clinical value of MRI, serum SCCA, and CA125 levels in the diagnosis of lymph node metastasis and para-uterine infiltration in cervical cancer

Chao Ran, Jian Sun, Yunhui Qu, Na Long

World J Surg Oncol. 2021; 19: 343. Published online 2021 Dec 9. doi: 10.1186/s12957-021-02448-3

PMCID:: PMC8656033

Abstract Article PDF–1.4M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 760717418.

Rho‐associated protein kinase‐dependent moesin phosphorylation is required for PD‐L1 stabilization in breast cancer

Fanbiao Meng, Yang Su, Bo Xu

Mol Oncol. 2020 Nov; 14(11): 2701–2712. Published online 2020 Oct 3. doi: 10.1002/1878-0261.12804

PMCID:: PMC7607174

Abstract Article PDF–4.2M

Select item 756688119.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 742732720.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

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