U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 156

1.
Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes
Maike Schuldt, Jamie R. Johnston, Huan He, Roy Huurman, Jiayi Pei, Magdalena Harakalova, Corrado Poggesi, Michelle Michels, Diederik W.D. Kuster, Jose R. Pinto, Jolanda van der Velden
J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: J Mol Cell Cardiol. 2021 Jan; 150: 77–90. Published online 2020 Oct 24. doi: 10.1016/j.yjmcc.2020.10.006
PMCID:
PMC10616699
AbstractArticlePDF–1.9M
2.
Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function
Maicon Landim-Vieira, Weikang Ma, Taejeong Song, Hosna Rastegarpouyani, Henry Gong, Isabella Leite Coscarella, Sylvia J. P. Bogaards, Stefan P. Conijn, Coen A. C. Ottenheijm, Hyun S. Hwang, Maria Papadaki, Bjorn C. Knollmann, Sakthivel Sadayappan, Thomas C. Irving, Vitold E. Galkin, P. Bryant Chase, Jose Renato Pinto
Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2221244120. Published online 2023 May 30. doi: 10.1073/pnas.2221244120
PMCID:
PMC10265946
AbstractArticlePDF–4.2M
3.
De Novo Asp219Val Mutation in Cardiac Tropomyosin Associated with Hypertrophic Cardiomyopathy
Andrey K. Tsaturyan, Elena V. Zaklyazminskaya, Margarita E. Polyak, Galina V. Kopylova, Daniil V. Shchepkin, Anastasia M. Kochurova, Anastasiia D. Gonchar, Sergey Y. Kleymenov, Natalia A. Koubasova, Sergey Y. Bershitsky, Alexander M. Matyushenko, Dmitrii I. Levitsky
Int J Mol Sci. 2023 Jan; 24(1): 18. Published online 2022 Dec 20. doi: 10.3390/ijms24010018
PMCID:
PMC9820293
AbstractArticlePDF–17M
4.
Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain
Kai M. Eggers, Ola Hammarsten, Sally J. Aldous, Louise Cullen, Jaimi H. Greenslade, Bertil Lindahl, William A. Parsonage, Christopher J. Pemberton, John W. Pickering, A. Mark Richards, Richard W. Troughton, Martin P. Than
PLoS One. 2022; 17(11): e0276645. Published online 2022 Nov 1. doi: 10.1371/journal.pone.0276645
PMCID:
PMC9624427
AbstractArticlePDF–826K
5.
Coronary atherosclerosis, cardiac troponin and interleukin-6 in patients with chest pain: Results from the PROMISE trial
Maros Ferencik, Thomas Mayrhofer, Michael T. Lu, Daniel O. Bittner, Hamed Emami, Stefan B. Puchner, Nandini M. Meyersohn, Alexander V. Ivanov, Elizabeth C. Adami, Deepak Voora, Geoffrey S. Ginsburg, James L. Januzzi, Pamela S. Douglas, Udo Hoffmann
JACC Cardiovasc Imaging. Author manuscript; available in PMC 2023 Aug 1.
Published in final edited form as: JACC Cardiovasc Imaging. 2022 Aug; 15(8): 1427–1438. Published online 2022 May 11. doi: 10.1016/j.jcmg.2022.03.016
PMCID:
PMC9353061
AbstractArticlePDF–937K
6.
Allele-specific silencing by RNAi of R92Q and R173W mutations in cardiac troponin T
Loredana Migliore, Federico Galvagni, Enrico Pierantozzi, Vincenzo Sorrentino, Daniela Rossi
Exp Biol Med (Maywood) 2022 May; 247(10): 805–814. Published online 2022 Jan 22. doi: 10.1177/15353702211072453
PMCID:
PMC9160939
AbstractArticlePDF–2.4M
7.
Dynamic Changes of High-Sensitivity Troponin T Concentration During Infancy: Clinical Implications
Petr JEHLICKA, Daniel RAJDL, Eva SLADKOVA, Aneta SYKOROVA, Josef SYKORA
Physiol Res. 2021 Feb; 70(1): 27–32. Published online 2021 Jan 14. doi: 10.33549/physiolres.934453
PMCID:
PMC8820510
AbstractArticlePDF–778K
8.
Isogenic human pluripotent stem cell disease models reveal ABRA deficiency underlies cTnT mutation-induced familial dilated cardiomyopathy
Bin Li, Yongkun Zhan, Qianqian Liang, Chen Xu, Xinyan Zhou, Huanhuan Cai, Yufan Zheng, Yifan Guo, Lei Wang, Wenqing Qiu, Baiping Cui, Chao Lu, Ruizhe Qian, Ping Zhou, Haiyan Chen, Yun Liu, Sifeng Chen, Xiaobo Li, Ning Sun
Protein Cell. 2022 Jan; 13(1): 65–71. Published online 2021 Apr 22. doi: 10.1007/s13238-021-00843-w
PMCID:
PMC8776971
ArticlePDF–2.6M
9.
The ratio of cardiac troponin T to troponin I may indicate non-necrotic troponin release among COVID-19 patients
Ola Hammarsten, Pontus Ljungqvist, Björn Redfors, Mathias Wernbom, Hannes Widing, Bertil Lindahl, Sabin Salahuddin, Ruwayda Sammantar, Sandeep Jha, Annica Ravn-Fischer, Magnus Brink, Magnus Gisslen
Clin Chim Acta. 2022 Feb 15; 527: 33–37. Published online 2022 Jan 5. doi: 10.1016/j.cca.2021.12.030
PMCID:
PMC8744390
AbstractArticlePDF–587K
10.
A troponin T variant linked with pediatric dilated cardiomyopathy reduces the coupling of thin filament activation to myosin and calcium binding
Samantha K. Barrick, Lina Greenberg, Michael J. Greenberg
Mol Biol Cell. 2021 Aug 19; 32(18): 1677–1689. doi: 10.1091/mbc.E21-02-0082
PMCID:
PMC8684737
AbstractArticlePDF–8.5M
11.
The role of antibody-based troponin detection in cardiovascular disease: A critical assessment
Hui Ma, Arabelle Cassedy, Richard O'Kennedy
J Immunol Methods. 2021 Oct; 497: 113108. Published online 2021 Jul 28. doi: 10.1016/j.jim.2021.113108
PMCID:
PMC8412434
AbstractArticlePDF–1.8M
12.
Systemic inflammation induced by exacerbation of COPD or pneumonia in patients with COPD induces cardiac troponin elevation
Vidar Søyseth, Natalia Kononova, Anke Neukamm, Nils Henrik Holmedahl, Tor-Arne Hagve, Torbjorn Omland, Gunnar Einvik
BMJ Open Respir Res. 2021; 8(1): e000997. Published online 2021 Aug 27. doi: 10.1136/bmjresp-2021-000997
PMCID:
PMC8404456
AbstractArticlePDF–262K
13.
Troponin T Mutation as a Cause of Left Ventricular Systolic Dysfunction in a Young Patient with Previous Surgical Correction of Aortic Coarctation
Martina Caiazza, Michele Lioncino, Emanuele Monda, Francesco Di Fraia, Federica Verrillo, Roberta Pacileo, Federica Amodio, Marta Rubino, Annapaola Cirillo, Adelaide Fusco, Emanuele Romeo, Alessandra Scatteia, Santo Dellegrottaglie, Paolo Calabrò, Berardo Sarubbi, Anwar Baban, Giulia Frisso, Maria Giovanna Russo, Giuseppe Limongelli
Biomolecules. 2021 May; 11(5): 696. Published online 2021 May 6. doi: 10.3390/biom11050696
PMCID:
PMC8148585
AbstractArticlePDF–749K
14.
Mechanical dysfunction of the sarcomere induced by a pathogenic mutation in troponin T drives cellular adaptation
Sarah R. Clippinger, Paige E. Cloonan, Wei Wang, Lina Greenberg, W. Tom Stump, Paweorn Angsutararux, Jeanne M. Nerbonne, Michael J. Greenberg
J Gen Physiol. 2021 May 3; 153(5): e202012787. Published online 2021 Apr 15. doi: 10.1085/jgp.202012787
PMCID:
PMC8054178
AbstractArticlePDF–5.0M
15.
Development of a Cardiac Sarcomere Functional Genomics Platform to Enable Scalable Interrogation of Human TNNT2 Variants
Anthony M. Pettinato, Feria A. Ladha, David J. Mellert, Nicholas Legere, Rachel Cohn, Robert Romano, Ketan Thakar, Yu-Sheng Chen, J. Travis Hinson
Circulation. Author manuscript; available in PMC 2021 Dec 8.
Published in final edited form as: Circulation. 2020 Dec 8; 142(23): 2262–2275. Published online 2020 Oct 7. doi: 10.1161/CIRCULATIONAHA.120.047999
PMCID:
PMC7722228
AbstractArticlePDF–1.7M
16.
High sensitivity Troponin-T for prediction of adverse events in patients with COVID-19
Nikhil Singh, Rajeev K. Anchan, Stephanie A. Besser, Mark N. Belkin, Mark D. Cruz, Linda Lee, Dongbo Yu, Natasha Mehta, Ann B. Nguyen, Francis J. Alenghat
Biomarkers. 2020 : 1–8. Published online 2020 Nov 24. doi: 10.1080/1354750X.2020.1829056
PMCID:
PMC7711742
AbstractArticlePDF–1.0M
17.
Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients
Chee Jian Pua, Nevin Tham, Calvin W.L. Chin, Roddy Walsh, Chiea Chuen Khor, Christopher N. Toepfer, Giuliana G. Repetti, Amanda C. Garfinkel, Jourdan K. Ewoldt, Paige Cloonan, Christopher S. Chen, Shi Qi Lim, Jiashen Cai, Li Yang Loo, Siew Ching Kong, Charleston W.K. Chiang, Nicola Whiffin, Antonio de Marvao, Pei Min Lio, An An Hii, Cheng Xi Yang, Thu Thao Le, Yasmin Bylstra, Weng Khong Lim, Jing Xian Teo, Kallyandra Padilha, Gabriela V. Silva, Bangfen Pan, Risha Govind, Rachel J. Buchan, Paul J.R. Barton, Patrick Tan, Roger Foo, James W.L. Yip, Raymond C.C. Wong, Wan Xian Chan, Alexandre C. Pereira, Hak Chiaw Tang, Saumya Shekhar Jamuar, James S. Ware, Jonathan G. Seidman, Christine E. Seidman, Stuart A. Cook
Circ Genom Precis Med. 2020 Oct; 13(5): 424–434. Published online 2020 Aug 20. doi: 10.1161/CIRCGEN.119.002823
PMCID:
PMC7676617
AbstractArticlePDF–777K
18.
Increased Myocardial Oxygen Consumption Precedes Contractile Dysfunction in Hypertrophic Cardiomyopathy Caused by Pathogenic TNNT2 Gene Variants
Rahana Y. Parbhudayal, Hendrik J. Harms, Michelle Michels, Albert C. van Rossum, Tjeerd Germans, Jolanda van der Velden
J Am Heart Assoc. 2020 Apr 21; 9(8): e015316. Published online 2020 Apr 15. doi: 10.1161/JAHA.119.015316
PMCID:
PMC7428531
AbstractArticlePDF–1.0M
19.
TNNT2 as a potential biomarker for the progression and prognosis of colorectal cancer
Li Jing, Li Feng, Zhiguo Zhou, Shuai Shi, Ruoying Deng, Zhicong Wang, Yi Zhang, Zhixue Ren, Yibing Liu
Oncol Rep. 2020 Aug; 44(2): 628–636. Published online 2020 Jun 9. doi: 10.3892/or.2020.7637
PMCID:
PMC7336514
AbstractArticlePDF–1.4M
20.
Variant R94C in TNNT2‐Encoded Troponin T Predisposes to Pediatric Restrictive Cardiomyopathy and Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction
Jordan E. Ezekian, Sarah R. Clippinger, Jaquelin M. Garcia, Qixin Yang, Susan Denfield, Aamir Jeewa, William J. Dreyer, Wenxin Zou, Yuxin Fan, Hugh D. Allen, Jeffrey J. Kim, Michael J. Greenberg, Andrew P. Landstrom
J Am Heart Assoc. 2020 Mar 3; 9(5): e015111. Published online 2020 Feb 26. doi: 10.1161/JAHA.119.015111
PMCID:
PMC7335540
AbstractArticlePDF–1.3M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center