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Select item 109544701.

Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding

Paolo Pizzul, Erika Casari, Carlo Rinaldi, Marco Gnugnoli, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese

Nucleic Acids Res. 2024 Mar 21; 52(5): 2355–2371. Published online 2024 Jan 5. doi: 10.1093/nar/gkad1246

PMCID:: PMC10954470

Abstract Article PDF–2.4M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 99845324.

Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

Natalie Schindler, Matthias Tonn, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke

Nat Commun. 2023; 14: 1227. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36866-6

PMCID:: PMC9984532

Abstract Article PDF–3.0M

Select item 99768775.

The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase

Carlo Rinaldi, Paolo Pizzul, Erika Casari, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese

Nucleic Acids Res. 2023 Feb 28; 51(4): 1783–1802. Published online 2023 Feb 10. doi: 10.1093/nar/gkad062

PMCID:: PMC9976877

Abstract Article PDF–6.3M

Select item 98363486.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 92098117.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 91699138.

The ubiquitin–proteasome system regulates meiotic chromosome organization

Xiao Yang, Meihui Song, Ying Wang, Taicong Tan, Zhongyu Tian, Binyuan Zhai, Xuan Yang, Yingjin Tan, Yanding Cao, Shaojun Dai, Shunxin Wang, Liangran Zhang

Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17): e2106902119. Published online 2022 Apr 19. doi: 10.1073/pnas.2106902119

PMCID:: PMC9169913

Abstract Article PDF–2.1M

Select item 91175469.

Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection

Aditya Mojumdar, Nancy Adam, Jennifer A. Cobb

J Biol Chem. 2022 Jun; 298(6): 101937. Published online 2022 Apr 13. doi: 10.1016/j.jbc.2022.101937

PMCID:: PMC9117546

Abstract Article PDF–2.7M

Select item 906175310.

Mre11-Rad50 oligomerization promotes DNA double-strand break repair

Vera M. Kissling, Giordano Reginato, Eliana Bianco, Kristina Kasaciunaite, Janny Tilma, Gea Cereghetti, Natalie Schindler, Sung Sik Lee, Raphaël Guérois, Brian Luke, Ralf Seidel, Petr Cejka, Matthias Peter

Nat Commun. 2022; 13: 2374. Published online 2022 May 2. doi: 10.1038/s41467-022-29841-0

PMCID:: PMC9061753

Abstract Article PDF–4.3M

Select item 877559111.

Systematic Screening of Penetratin’s Protein Targets by Yeast Proteome Microarrays

Pramod Shah, Chien-Sheng Chen

Int J Mol Sci. 2022 Jan; 23(2): 712. Published online 2022 Jan 10. doi: 10.3390/ijms23020712

PMCID:: PMC8775591

Abstract Article PDF–5.0M

Select item 846274512.

The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks

Marco Gnugnoli, Erika Casari, Maria Pia Longhese

PLoS Genet. 2021 Sep; 17(9): e1009807. Published online 2021 Sep 14. doi: 10.1371/journal.pgen.1009807

PMCID:: PMC8462745

Abstract Article PDF–3.2M

Select item 842120413.

Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast

Laurence Decourty, Christophe Malabat, Emmanuel Frachon, Alain Jacquier, Cosmin Saveanu

Nucleic Acids Res. 2021 Sep 7; 49(15): 8535–8555. Published online 2021 Aug 6. doi: 10.1093/nar/gkab680

PMCID:: PMC8421204

Abstract Article PDF–2.9M

Select item 835352614.

The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription

David Z. Kochan, Julia S. P. Mawer, Jennifer Massen, Kiril Tishinov, Swati Parekh, Martin Graef, Anne Spang, Peter Tessarz

J Cell Sci. 2021 Aug 1; 134(15): jcs259051. Published online 2021 Aug 5. doi: 10.1242/jcs.259051

PMCID:: PMC8353526

Abstract Article

Select item 821968115.

Inhibition of MRN activity by a telomere protein motif

Freddy Khayat, Elda Cannavo, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr, Petr Cejka, Alessandro Bianchi

Nat Commun. 2021; 12: 3856. Published online 2021 Jun 22. doi: 10.1038/s41467-021-24047-2

PMCID:: PMC8219681

Abstract Article PDF–3.3M

Select item 811559916.

Mechanism of MRX inhibition by Rif2 at telomeres

Florian Roisné-Hamelin, Sabrina Pobiega, Kévin Jézéquel, Simona Miron, Jordane Dépagne, Xavier Veaute, Didier Busso, Marie-Hélène Le Du, Isabelle Callebaut, Jean-Baptiste Charbonnier, Philippe Cuniasse, Sophie Zinn-Justin, Stéphane Marcand

Nat Commun. 2021; 12: 2763. Published online 2021 May 12. doi: 10.1038/s41467-021-23035-w

PMCID:: PMC8115599

Abstract Article PDF–3.9M

Select item 811281717.

A role for the Mre11–Rad50–Xrs2 complex in gene expression and chromosome organization

Romain Forey, Antoine Barthe, Mireille Tittel-Elmer, Maxime Wery, Marie-Bénédicte Barrault, Cécile Ducrot, Andrew Seeber, Nils Krietenstein, Ugo Szachnowski, Magdalena Skrzypczak, Krzysztof Ginalski, Maga Rowicka, Jennifer Cobb, Oliver J. Rando, Julie Soutourina, Michel Werner, Karine Dubrana, Susan M. Gasser, Antonin Morillon, Philippe Pasero, Armelle Lengronne, Jérôme Poli

Mol Cell. Author manuscript; available in PMC 2021 May 11.

Published in final edited form as: Mol Cell. 2021 Jan 7; 81(1): 183–197.e6. Published online 2020 Dec 4. doi: 10.1016/j.molcel.2020.11.010

PMCID:: PMC8112817

Abstract Article PDF–2.5M

Select item 804059818.

Modeling DNA trapping of anticancer therapeutic targets using missense mutations identifies dominant synthetic lethal interactions

Akil Hamza, Leanne Amitzi, Lina Ma, Maureen R. M. Driessen, Nigel J. O'Neil, Philip Hieter

Proc Natl Acad Sci U S A. 2021 Apr 6; 118(14): e2100240118. Published online 2021 Mar 29. doi: 10.1073/pnas.2100240118

PMCID:: PMC8040598

Abstract Article PDF–1.5M

Select item 802831419.

Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners

Antonio Marsella, Elisa Gobbini, Corinne Cassani, Renata Tisi, Elda Cannavo, Giordano Reginato, Petr Cejka, Maria Pia Longhese

Cell Rep. 2021 Mar 30; 34(13): 108906. Published online 2021 Mar 30. doi: 10.1016/j.celrep.2021.108906

PMCID:: PMC8028314

Abstract Article

Select item 778828520.

A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans

Marie Chansel-Da Cruz, Marcel Hohl, Ilaria Ceppi, Laëtitia Kermasson, Laurence Maggiorella, Mauro Modesti, Jean-Pierre de Villartay, Talia Ileri, Petr Cejka, John H.J. Petrini, Patrick Revy

Cell Rep. 2020 Dec 29; 33(13): 108559. Published online 2020 Dec 29. doi: 10.1016/j.celrep.2020.108559

PMCID:: PMC7788285

Abstract Article

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