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Select item 109585851.

Human Genetic Variation at rs10071329 Correlates With Adiposity-Related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function

Mi Huang, Rashmi B. Prasad, Daniel E. Coral, Line Hjort, Daniel T.R. Minja, Hindrik Mulder, Paul W. Franks, Sebastian Kalamajski

Diabetes. 2024 Apr; 73(4): 637–645. Published online 2024 Jan 8. doi: 10.2337/db23-0531

PMCID:: PMC10958585

Abstract Article PDF–70M

Select item 108357652.

Pulling rank with RNA: RANKL promotes the association of PGC-1β/RNA complexes with NCoR/HDAC3 to activate gene expression in osteoclasts

Haydee M. Torres, Dongwook Yeo, Jennifer J. Westendorf

Mol Cell. Author manuscript; available in PMC 2024 Feb 2.

Published in final edited form as: Mol Cell. 2023 Oct 5; 83(19): 3397–3399. doi: 10.1016/j.molcel.2023.09.012

PMCID:: PMC10835765

Abstract Article PDF–462K

Select item 99265143.

LMP1 mediates tumorigenesis through persistent epigenetic modifications and PGC1β upregulation

Siliang Chen, Ping Zhang, Jia Feng, Rui Li, Junhui Chen, Wei V. Zheng, Hongyu Zhang, Paul Yao

Oncol Rep. 2023 Mar; 49(3): 53. Published online 2023 Feb 2. doi: 10.3892/or.2023.8490

PMCID:: PMC9926514

Abstract Article PDF–3.7M

Select item 98051994.

Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population

Boyang Chen, Yafeng Wang, Weifeng Tang, Yu Chen, Chao Liu, Mingqiang Kang, Jinbiao Xie

BMC Med Genomics. 2022; 15: 274. Published online 2022 Dec 31. doi: 10.1186/s12920-022-01428-0

PMCID:: PMC9805199

Abstract Article PDF–944K

Select item 97418795.

Analysis of Metabolic Regulators PGC1-α and PGC1-β in Oral Squamous Cell Carcinoma with and without Hyperglycemia

Tamizh Paavai Thamizhanambi, Annasamy Rameshkumar, Ramadoss Ramya, Rajkumar Krishnan, Thayalan Dineshkumar, Gunasekaran Nandhini

Asian Pac J Cancer Prev. 2022 Aug; 23(8): 2797–2803. doi: 10.31557/APJCP.2022.23.8.2797

PMCID:: PMC9741879

Abstract Article PDF–332K

Select item 93597166.

PGC1α/β Expression Predicts Therapeutic Response to Oxidative Phosphorylation Inhibition in Ovarian Cancer

Carmen Ghilardi, Catarina Moreira-Barbosa, Laura Brunelli, Paola Ostano, Nicolò Panini, Monica Lupi, Alessia Anastasia, Fabio Fiordaliso, Monica Salio, Laura Formenti, Massimo Russo, Edoardo Arrigoni, Ferdinando Chiaradonna, Giovanna Chiorino, Giulio Draetta, Joseph R. Marszalek, Christopher P. Vellano, Roberta Pastorelli, MariaRosa Bani, Alessandra Decio, Raffaella Giavazzi

Cancer Res. 2022 Apr 1; 82(7): 1423–1434. Published online 2022 Feb 7. doi: 10.1158/0008-5472.CAN-21-1223

PMCID:: PMC9359716

Abstract Article PDF–1.4M

Select item 83851107.

Decreased PGC1β expression results in disrupted human erythroid differentiation, impaired hemoglobinization and cell cycle exit

Taha Sen, Jun Chen, Sofie Singbrant

Sci Rep. 2021; 11: 17129. Published online 2021 Aug 24. doi: 10.1038/s41598-021-96585-0

PMCID:: PMC8385110

Abstract Article PDF–3.2M

Select item 82827648.

N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas

Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017

PMCID:: PMC8282764

Abstract Article PDF–3.4M

Select item 82584629.

PI3K/AKT phosphorylation activates ERRα by upregulating PGC-1α and PGC-1β in gallbladder cancer

Lei Wang, Mengmeng Yang, Huihan Jin

Mol Med Rep. 2021 Aug; 24(2): 613. Published online 2021 Jun 28. doi: 10.3892/mmr.2021.12252

PMCID:: PMC8258462

Abstract Article PDF–2.1M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 812912611.

UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinoma

Junjie Xu, Lin Ji, Yeling Ruan, Zhe Wan, Zhongjie Lin, Shunjie Xia, Liye Tao, Junhao Zheng, Liuxin Cai, Yifan Wang, Xiao Liang, Xiujun Cai

Signal Transduct Target Ther. 2021; 6: 190. Published online 2021 May 18. doi: 10.1038/s41392-021-00594-4

PMCID:: PMC8129126

Abstract Article PDF–7.4M

Select item 810908112.

Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis

Hui Zhang, Aifei Wang, Guangsi Shen, Xiao Wang, Gongwen Liu, Fan Yang, Bin Chen, Mingyong Wang, Youjia Xu

Aging (Albany NY) 2021 Apr 30; 13(8): 11296–11314. Published online 2021 Apr 4. doi: 10.18632/aging.202817

PMCID:: PMC8109081

Abstract Article PDF–2.2M

Select item 683147013.

Yin Yang 1 facilitates hepatocellular carcinoma cell lipid metabolism and tumor progression by inhibiting PGC-1β-induced fatty acid oxidation

Yanjun Li, Vivi Kasim, Xuesong Yan, Lang Li, Ian Timothy Sembiring Meliala, Can Huang, Zhuolin Li, Ke Lei, Guanbin Song, Xiaodong Zheng, Shourong Wu

Theranostics. 2019; 9(25): 7599–7615. Published online 2019 Oct 14. doi: 10.7150/thno.34931

PMCID:: PMC6831470

Abstract Article PDF–3.6M

Select item 649212414.

Reduced cardiomyocyte Na⁺ current in the age‐dependent murine Pgc‐1β^−/− model of ventricular arrhythmia

Shiraz Ahmad, Haseeb Valli, Robert Smyth, Anita Y. Jiang, Kamalan Jeevaratnam, Hugh R. Matthews, Christopher L.‐H. Huang

J Cell Physiol. 2019 Apr; 234(4): 3921–3932. Published online 2018 Aug 26. doi: 10.1002/jcp.27183

PMCID:: PMC6492124

Abstract Article PDF–978K

Select item 636771315.

Promoter methylation of PGC1A and PGC1B predicts cancer incidence in a veteran cohort

Jacob K Kresovich, Brian T Joyce, Tao Gao, Yinan Zheng, Zhou Zhang, Christopher J Achenbach, Robert L Murphy, Allan C Just, Jincheng Shen, Hushan Yang, Pantel Vokonas, Joel Schwartz, Andrea A Baccarelli, Lifang Hou

Epigenomics. 2018 Jun; 10(6): 733–742. Published online 2018 Jun 11. doi: 10.2217/epi-2017-0141

PMCID:: PMC6367713

Abstract Article PDF–1013K

Select item 628960316.

Peroxisome proliferator-activated receptor γ coactivator family members competitively regulate hepatitis b virus biosynthesis

Rasha E. Shalaby, Saira Iram, Claudia E. Oropeza, Alan McLachlan

Virology. Author manuscript; available in PMC 2020 Jan 2.

Published in final edited form as: Virology. 2019 Jan 2; 526: 214–221. Published online 2018 Nov 10. doi: 10.1016/j.virol.2018.10.027

PMCID:: PMC6289603

Abstract Article PDF–1.1M

Select item 616668217.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 613767318.

Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis

Kate A. Parham, Julia R. Zebol, Katie L. Tooley, Wai Y. Sun, Lachlan M. Moldenhauer, Michaelia P. Cockshell, Briony L. Gliddon, Paul A. Moretti, Gabor Tigyi, Stuart M. Pitson, Claudine S. Bonder

FASEB J. 2015 Sep; 29(9): 3638–3653. Published online 2015 May 18. doi: 10.1096/fj.14-261289

PMCID:: PMC6137673

Abstract Article

Select item 612025219.

PGC1β regulates multiple myeloma tumor growth through LDHA‐mediated glycolytic metabolism

Hongyu Zhang, Ling Li, Qi Chen, Min Li, Jia Feng, Ying Sun, Rong Zhao, Yin Zhu, Yang Lv, Zhigang Zhu, Xiaodong Huang, Weiguo Xie, Wei Xiang, Paul Yao

Mol Oncol. 2018 Sep; 12(9): 1579–1595. Published online 2018 Aug 14. doi: 10.1002/1878-0261.12363

PMCID:: PMC6120252

Abstract Article PDF–1.2M

Select item 600288120.

PGC1β Organizes the Osteoclast Cytoskeleton by Mitochondrial Biogenesis and Activation

Yan Zhang, Nidhi Rohatgi, Deborah J. Veis, Joel Schilling, Steven L. Teitelbaum, Wei Zou

J Bone Miner Res. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: J Bone Miner Res. 2018 Jun; 33(6): 1114–1125. Published online 2018 Mar 11. doi: 10.1002/jbmr.3398

PMCID:: PMC6002881

Abstract Article PDF–1.8M

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