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Select item 111597081.

Reduction of 15‐hydroxyprostaglandin dehydrogenase expression is an independent predictor of poor survival associated with enhanced cell proliferation in gastric adenocarcinoma

Hiroshi Tatsuwaki, Tetsuya Tanigawa, Toshio Watanabe, Hirohisa Machida, Hirotoshi Okazaki, Hirokazu Yamagami, Masatsugu Shiba, Kenji Watanabe, Kazunari Tominaga, Yasuhiro Fujiwara, Nobuhide Oshitani, Kazuya Muguruma, Tetsuji Sawada, Kosei Hirakawa, Kazuhide Higuchi, Tetsuo Arakawa

Cancer Sci. 2010 Feb; 101(2): 550–558. Published online 2009 Oct 10. doi: 10.1111/j.1349-7006.2009.01390.x

PMCID:: PMC11159708

Abstract Article PDF–926K

Select item 108152922.

Reclassification of the HPGD p.Ala13Glu variant causing primary hypertrophic osteoarthropathy

Juan J. Alban, Alejandra Arango-Ramirez, Jorge A. Olave-Rodriguez, Jose A. Nastasi-Catanese, Lisa X. Rodriguez

Cold Spring Harb Mol Case Stud. 2023 Dec; 9(4): a006291. doi: 10.1101/mcs.a006291

PMCID:: PMC10815292

Abstract Article PDF–1.8M

Select item 92544673.

Clinical and biochemical characteristics of 12 Chinese primary hypertrophic osteoarthropathy patients with HPGD mutations

Qi Lu, Yang Xu, Shanshan Li, Zeng Zhang, Jiagen Sheng, Zhenlin Zhang

Int J Biol Sci. 2022; 18(9): 3908–3917. Published online 2022 Jun 6. doi: 10.7150/ijbs.71261

PMCID:: PMC9254467

Abstract Article PDF–1.2M

Select item 88983024.

Epigenetic Silencing of 15-Hydroxyprostaglandin Dehydrogenase by Histone Methyltransferase EHMT2/G9a in Cholangiocarcinoma

Jinqiang Zhang, Weina Chen, Wenbo Ma, Kyoungsub Song, Sean Lee, Chang Han, Tong Wu

Mol Cancer Res. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Mol Cancer Res. 2022 Mar 1; 20(3): 350–360. doi: 10.1158/1541-7786.MCR-21-0536

PMCID:: PMC8898302

Abstract Article PDF–1.7M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79383286.

Inhibition of Prostaglandin Degrading Enzyme 15-PGDH Rejuvenates Aged Muscle Mass and Strength

A.R. Palla, M. Ravichandran, Y.X. Wang, L. Alexandrova, A.V. Yang, P. Kraft, C.A. Holbrook, C.M. Schürch, A.T.V. Ho, H.M. Blau

Science. Author manuscript; available in PMC 2021 Mar 8.

Published in final edited form as: Science. 2021 Jan 29; 371(6528): eabc8059. Published online 2020 Dec 10. doi: 10.1126/science.abc8059

PMCID:: PMC7938328

Abstract Article PDF–3.3M

Select item 64436537.

miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer

Nicholas J. Monteleone, Ashleigh E. Moore, Joseph R. Iacona, Carol S. Lutz, Dan A. Dixon

Sci Rep. 2019; 9: 5405. Published online 2019 Apr 1. doi: 10.1038/s41598-019-41862-2

PMCID:: PMC6443653

Abstract Article PDF–2.5M

Select item 62951658.

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression

Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-François Rual, James Douglas Engel

Genes Dev. 2018 Dec 1; 32(23-24): 1537–1549. doi: 10.1101/gad.318436.118

PMCID:: PMC6295165

Abstract Article PDF–3.5M

Select item 61929999.

Down-regulation of HPGD by miR-146b-3p promotes cervical cancer cell proliferation, migration and anchorage-independent growth through activation of STAT3 and AKT pathways

Shuihong Yao, Jingyun Xu, Kaixuan Zhao, Pengxia Song, Qin Yan, Weifei Fan, Wan Li, Chun Lu

Cell Death Dis. 2018 Nov; 9(11): 1055. Published online 2018 Oct 17. doi: 10.1038/s41419-018-1059-y

Correction in:: Cell Death Dis. 2023 Jun; 14(6): 377.

PMCID:: PMC6192999

Abstract Article PDF–4.6M

Select item 579782410.

Downregulation of 15‐hydroxyprostaglandin dehydrogenase by interleukin‐1β from activated macrophages leads to poor prognosis in pancreatic cancer

Kota Arima, Yoshihiro Komohara, Luke Bu, Masayo Tsukamoto, Rumi Itoyama, Keisuke Miyake, Tomoyuki Uchihara, Yoko Ogata, Shigeki Nakagawa, Hirohisa Okabe, Katsunori Imai, Daisuke Hashimoto, Akira Chikamoto, Yo‐ichi Yamashita, Hideo Baba, Takatsugu Ishimoto

Cancer Sci. 2018 Feb; 109(2): 462–470. Published online 2018 Jan 27. doi: 10.1111/cas.13467

PMCID:: PMC5797824

Abstract Article PDF–1.3M

Select item 572186711.

Sex Differential in 15‐Hydroxyprostaglandin Dehydrogenase Levels in the Lumen of Human Intracranial Aneurysms

Nohra Chalouhi, Pascal Jabbour, Mario Zanaty, Robert M. Starke, James Torner, Daichi Nakagawa, David M. Hasan

J Am Heart Assoc. 2017 Oct; 6(10): e006639. Published online 2017 Oct 17. doi: 10.1161/JAHA.117.006639

PMCID:: PMC5721867

Abstract Article PDF–204K

Select item 542321312.

Non‐canonical WNT5A signaling up‐regulates the expression of the tumor suppressor 15‐PGDH and induces differentiation of colon cancer cells

Lubna M. Mehdawi, Chandra Prakash Prasad, Roy Ehrnström, Tommy Andersson, Anita Sjölander

Mol Oncol. 2016 Nov; 10(9): 1415–1429. Published online 2016 Aug 1. doi: 10.1016/j.molonc.2016.07.011

PMCID:: PMC5423213

Abstract Article PDF–2.9M

Select item 538927913.

Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer

Cunxi Li, Bhuminder Singh, Ramona Graves-Deal, Haiting Ma, Alina Starchenko, William H. Fry, Yuanyuan Lu, Yang Wang, Galina Bogatcheva, Mohseen P. Khan, Ginger L. Milne, Shilin Zhao, Gregory Daniel Ayers, Nenggan Li, Huaying Hu, Mary Kay Washington, Timothy J. Yeatman, Oliver G. McDonald, Qi Liu, Robert J. Coffey

Proc Natl Acad Sci U S A. 2017 Apr 4; 114(14): E2852–E2861. Published online 2017 Mar 20. doi: 10.1073/pnas.1618297114

PMCID:: PMC5389279

Abstract Article PDF–1.8M

Select item 500050114.

MicroRNA-21 regulates prostaglandin E2 signaling pathway by targeting 15-hydroxyprostaglandin dehydrogenase in tongue squamous cell carcinoma

Qianting He, Zujian Chen, Qian Dong, Leitao Zhang, Dan Chen, Aditi Patel, Ajay Koya, Xianghong Luan, Robert J. Cabay, Yang Dai, Anxun Wang, Xiaofeng Zhou

BMC Cancer. 2016; 16(1): 685. Published online 2016 Aug 25. doi: 10.1186/s12885-016-2716-0

PMCID:: PMC5000501

Abstract Article PDF–725K

Select item 454560615.

Expression and Cellular Localization of 15-Hydroxy-Prostaglandin-Dehydrogenase in Abdominal Aortic Aneurysm

David Solà-Villà, Jaime-Félix Dilmé, Cristina Rodríguez, Begoña Soto, Luis Vila, José-Román Escudero, José Martínez-González, Mercedes Camacho

PLoS One. 2015; 10(8): e0136201. Published online 2015 Aug 19. doi: 10.1371/journal.pone.0136201

PMCID:: PMC4545606

Abstract Article PDF–1.6M

Select item 452591216.

15-PGDH expression as a predictive factor response to neoadjuvant chemotherapy in advanced gastric cancer

Min Hu, Kai Li, Ninu Maskey, Zhigao Xu, ChunWei Peng, Sufang Tian, Yan Li, Guifang Yang

Int J Clin Exp Pathol. 2015; 8(6): 6910–6918. Published online 2015 Jun 1.

PMCID:: PMC4525912

Abstract Article PDF–1.4M

Select item 448112617.

Inhibition of the Prostaglandin Degrading Enzyme 15-PGDH Potentiates Tissue Regeneration

Yongyou Zhang, Amar Desai, Sung Yeun Yang, Ki Beom Bae, Monika I. Antczak, Stephen P. Fink, Shruti Tiwari, Joseph E. Willis, Noelle S. Williams, Dawn M. Dawson, David Wald, Wei-Dong Chen, Zhenghe Wang, Lakshmi Kasturi, Gretchen A. Larusch, Lucy He, Fabio Cominelli, Luca Di Martino, Zora Djuric, Ginger L. Milne, Mark Chance, Juan Sanabria, Chris Dealwis, Debra Mikkola, Jacinth Naidoo, Shuguang Wei, Hsin-Hsiung Tai, Stanton L. Gerson, Joseph M. Ready, Bruce Posner, James K. V. Willson, Sanford D. Markowitz

Science. Author manuscript; available in PMC 2015 Dec 12.

Published in final edited form as: Science. 2015 Jun 12; 348(6240): aaa2340. doi: 10.1126/science.aaa2340

PMCID:: PMC4481126

Abstract Article PDF–1.3M

Select item 438540218.

Multiple Drug Resistance-Associated Protein 4 (MRP4), Prostaglandin Transporter (PGT), and 15-Hydroxyprostaglandin Dehydrogenase (15-PGDH) as Determinants of PGE₂ Levels in Cancer

Tyler J. Kochel, Amy M. Fulton

Prostaglandins Other Lipid Mediat. Author manuscript; available in PMC 2015 Apr 4.

Published in final edited form as: Prostaglandins Other Lipid Mediat. 2015 Jan-Mar; 0: 99–103. Published online 2014 Nov 27. doi: 10.1016/j.prostaglandins.2014.11.003