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Select item 108232901.

Extracellular vesicle‐encapsulated microRNA‐296‐3p from cancer‐associated fibroblasts promotes ovarian cancer development through regulation of the PTEN/AKT and SOCS6/STAT3 pathways

Luyao Sun, Miaola Ke, Mengyuan Yin, Ying Zeng, Yutong Ji, Yiming Hu, Songbin Fu, Chunyu Zhang

Cancer Sci. 2024 Jan; 115(1): 155–169. Published online 2023 Nov 16. doi: 10.1111/cas.16014

PMCID:: PMC10823290

Abstract Article PDF–25M

Select item 104998212.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 89515563.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 86674224.

Down-regulation of SOCS6: an unfavorable prognostic factor for gastrointestinal stromal tumor proven by survival analysis

Jun Ouyang, Tailai An, Yan Wang, Xiaofang Lu, Yawei Zhang, Xiaokun Wang, Xinhua Zhang, Changhua Zhang

Diagn Pathol. 2021; 16: 113. Published online 2021 Dec 12. doi: 10.1186/s13000-021-01172-6

PMCID:: PMC8667422

Abstract Article PDF–2.1M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79537566.

SOCS6 promotes radiosensitivity and decreases cancer cell stemness in esophageal squamous cell carcinoma by regulating c-Kit ubiquitylation

Xuanzi Sun, Yuchen Sun, Jing Li, Xu Zhao, Xiaobo Shi, Tuotuo Gong, Shupei Pan, Zhongqiang Zheng, Xiaozhi Zhang

Cancer Cell Int. 2021; 21: 165. Published online 2021 Mar 12. doi: 10.1186/s12935-021-01859-2

PMCID:: PMC7953756

Abstract Article PDF–4.6M

Select item 78847777.

Circular RNA circ_103820 suppresses lung cancer tumorigenesis by sponging miR-200b-3p to release LATS2 and SOCS6

Yongbin Chi, Wenlong Zheng, Guangyu Bao, Lifeng Wu, Xiaoxue He, Ruyi Gan, Yan Shen, Xudong Yin, Mingming Jin

Cell Death Dis. 2021 Feb; 12(2): 185. Published online 2021 Feb 15. doi: 10.1038/s41419-021-03472-7

PMCID:: PMC7884777

Abstract Article PDF–3.4M

Select item 72983478.

miR-155-5p Implicates in the Pathogenesis of Renal Fibrosis via Targeting SOCS1 and SOCS6

Wanfen Zhang, Xiaoping Li, Yushang Tang, Cheng Chen, Ran Jing, Tongqiang Liu

Oxid Med Cell Longev. 2020; 2020: 6263921. Published online 2020 Jun 6. doi: 10.1155/2020/6263921

PMCID:: PMC7298347

Abstract Article PDF–2.1M

Select item 71699839.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 715369510.

ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection

Ruth Hüttenhain, Jiewei Xu, Lily A. Burton, David E. Gordon, Judd F. Hultquist, Jeffrey R. Johnson, Laura Satkamp, Joseph Hiatt, David Y. Rhee, Kheewoong Baek, David C. Crosby, Alan D. Frankel, Alexander Marson, J. Wade Harper, Arno F. Alpi, Brenda A. Schulman, John D. Gross, Nevan J. Krogan

Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 10.

Published in final edited form as: Cell Host Microbe. 2019 Jul 10; 26(1): 86–99.e7. Published online 2019 Jun 25. doi: 10.1016/j.chom.2019.05.008

PMCID:: PMC7153695

Abstract Article PDF–2.6M

Select item 636863211.

miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC

Yang Xia, Ke Wei, Feng-Ming Yang, Liu-Qing Hu, Chun-Feng Pan, Xiang-Long Pan, Wei-Bing Wu, Jun Wang, Wei Wen, Zhi-Cheng He, Jing Xu, Xin-Feng Xu, Quan Zhu, Liang Chen

Cell Death Dis. 2019 Feb; 10(2): 112. Published online 2019 Feb 8. doi: 10.1038/s41419-019-1390-y

Correction in:: Cell Death Dis. 2020 Apr; 11(4): 261.

PMCID:: PMC6368632

Abstract Article PDF–3.7M

Select item 608431812.

PTENP1 inhibits the growth of esophageal squamous cell carcinoma by regulating SOCS6 expression and correlates with disease prognosis

Tuotuo Gong, Shuyu Zheng, Shan Huang, Shenbo Fu, Xuanwei Zhang, Shupei Pan, Tian Yang, Yuchen Sun, Ya Wang, Beina Hui, Jia Guo, Xiaozhi Zhang

Mol Carcinog. 2017 Dec; 56(12): 2610–2619. Published online 2017 Aug 21. doi: 10.1002/mc.22705

PMCID:: PMC6084318

Abstract Article PDF–2.0M

Select item 558980013.

SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms

Carissa Pilling, Jonathan A. Cooper

Sci Rep. 2017; 7: 10838. Published online 2017 Sep 7. doi: 10.1038/s41598-017-11040-3

PMCID:: PMC5589800

Abstract Article PDF–5.5M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 540059115.

miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6

Sebastiano Rontauroli, Ruggiero Norfo, Valentina Pennucci, Roberta Zini, Samantha Ruberti, Elisa Bianchi, Simona Salati, Zelia Prudente, Chiara Rossi, Vittorio Rosti, Paola Guglielmelli, Giovanni Barosi, Alessandro Vannucchi, Enrico Tagliafico, Rossella Manfredini

Oncotarget. 2017 Mar 28; 8(13): 21380–21397. Published online 2017 Feb 9. doi: 10.18632/oncotarget.15226

PMCID:: PMC5400591

Abstract Article PDF–9.0M

Select item 461721116.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 438092817.

Phospho-tyrosine dependent protein–protein interaction network

Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl

Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968

PMCID:: PMC4380928

Abstract Article PDF–1.9M

Select item 428340418.

Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

Xin Hong, Hung Thanh Nguyen, Qingfeng Chen, Rui Zhang, Zandra Hagman, P Mathijs Voorhoeve, Stephen M Cohen

EMBO J. 2014 Nov 3; 33(21): 2447–2457. Published online 2014 Sep 1. doi: 10.15252/embj.201489385

PMCID:: PMC4283404

Abstract Article PDF–1.6M

Select item 413450619.

Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer

E Letellier, M Schmitz, K Baig, N Beaume, C Schwartz, S Frasquilho, L Antunes, N Marcon, P V Nazarov, L Vallar, J Even, S Haan

Br J Cancer. 2014 Aug 12; 111(4): 726–735. Published online 2014 Jul 15. doi: 10.1038/bjc.2014.377

PMCID:: PMC4134506

Abstract Article PDF–1.7M

Select item 408311020.

Enhanced Prediction of Src Homology 2 (SH2) Domain Binding Potentials Using a Fluorescence Polarization-derived c-Met, c-Kit, ErbB, and Androgen Receptor Interactome

Kin K. Leung, Ronald J. Hause, Jr., John L. Barkinge, Mark F. Ciaccio, Chih-Pin Chuu, Richard B. Jones

Mol Cell Proteomics. 2014 Jul; 13(7): 1705–1723. Published online 2014 Apr 12. doi: 10.1074/mcp.M113.034876

PMCID:: PMC4083110

Abstract Article PDF–6.6M

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