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Select item 111510921.

Sec18 binds the tethering/SM complex HOPS to engage the Qc-SNARE for membrane fusion

Amy Orr, William Wickner

Mol Biol Cell. 2024 May 1; 35(5): ar71. Published online 2024 Apr 16. doi: 10.1091/mbc.E24-02-0060

PMCID:: PMC11151092

Abstract Article PDF–2.6M

Select item 109784972.

The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes

Nadia Füllbrunn, Raffaele Nicastro, Muriel Mari, Janice Griffith, Eric Herrmann, René Rasche, Ann-Christin Borchers, Kathrin Auffarth, Daniel Kümmel, Fulvio Reggiori, Claudio De Virgilio, Lars Langemeyer, Christian Ungermann

J Cell Biol. 2024 Jun 3; 223(6): e202305038. Published online 2024 Mar 27. doi: 10.1083/jcb.202305038

PMCID:: PMC10978497

Abstract Article PDF–7.4M

Select item 108724773.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001384.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102977005.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102922106.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 102350867.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 102333688.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 98363489.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 959208210.

Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery

Dmitry Shvarev, Jannis Schoppe, Caroline König, Angela Perz, Nadia Füllbrunn, Stephan Kiontke, Lars Langemeyer, Dovile Januliene, Kilian Schnelle, Daniel Kümmel, Florian Fröhlich, Arne Moeller, Christian Ungermann

eLife. 2022; 11: e80901. Published online 2022 Sep 13. doi: 10.7554/eLife.80901

PMCID:: PMC9592082

Abstract Article PDF–7.4M

Select item 928602311.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 920981112.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 880492913.

Oxidative stress protein Oxr1 promotes V‐ATPase holoenzyme disassembly in catalytic activity‐independent manner

Md. Murad Khan, Seowon Lee, Sergio Couoh‐Cardel, Rebecca A Oot, Hyunmin Kim, Stephan Wilkens, Soung‐Hun Roh

EMBO J. 2022 Feb 1; 41(3): e109360. Published online 2021 Dec 17. doi: 10.15252/embj.2021109360

PMCID:: PMC8804929

Abstract Article PDF–5.5M

Select item 876255414.

Molecular species selectivity of lipid transport creates a mitochondrial sink for di‐unsaturated phospholipids

Mike F Renne, Xue Bao, Margriet WJ Hokken, Adolf S Bierhuizen, Martin Hermansson, Richard R Sprenger, Tom A Ewing, Xiao Ma, Ruud C Cox, Jos F Brouwers, Cedric H De Smet, Christer S Ejsing, Anton IPM de Kroon

EMBO J. 2022 Jan 17; 41(2): e106837. Published online 2021 Dec 7. doi: 10.15252/embj.2020106837

PMCID:: PMC8762554

Abstract Article PDF–1.0M

Select item 869397215.

Phosphatidylinositol and phosphatidylinositol-3-phosphate activate HOPS to catalyze SNARE assembly, allowing small headgroup lipids to support the terminal steps of membrane fusion

Thomas Torng, William Wickner

Mol Biol Cell. 2021 Nov 1; 32(21): ar19. doi: 10.1091/mbc.E21-07-0373

PMCID:: PMC8693972

Abstract Article PDF–4.2M

Select item 868475816.

Yeast Nst1 is a novel component of P-bodies and is a specific suppressor of proteasome base assembly defects

Chin Leng Cheng, Michael K. Wong, Mark Hochstrasser

Mol Biol Cell. 2021 Oct 1; 32(20): ar6. doi: 10.1091/mbc.E21-04-0178

PMCID:: PMC8684758

Abstract Article PDF–2.7M

Select item 861656017.

Golgi membrane protein Erd1 Is essential for recycling a subset of Golgi glycosyltransferases

Richa Sardana, Carolyn M Highland, Beth E Straight, Christopher F Chavez, J Christopher Fromme, Scott D Emr

eLife. 2021; 10: e70774. Published online 2021 Nov 25. doi: 10.7554/eLife.70774

PMCID:: PMC8616560

Abstract Article PDF–3.2M

Select item 851348518.

Tombusviruses Target a Major Crossroad in the Endocytic and Recycling Pathways via Co-opting Rab7 Small GTPase

Zhike Feng, Jun-ichi Inaba, Peter D. Nagy

J Virol. 2021 Nov; 95(21): e01076-21. Prepublished online 2021 Aug 18. Published online 2021 Oct 13. doi: 10.1128/JVI.01076-21

PMCID:: PMC8513485

Abstract Article PDF–4.2M

Select item 838662819.

PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes

Hongjun Zhang, Jiao Zhou, Peng Xiao, Yong Lin, Xin Gong, Shiyan Liu, Qingjia Xu, Minjin Wang, Haiyan Ren, Mengji Lu, Yuan Wang, Jing Zhu, Zhiping Xie, Huihui Li, Kefeng Lu

Autophagy. 2021; 17(8): 1907–1917. Published online 2020 Jul 30. doi: 10.1080/15548627.2020.1796321