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Select item 112139331.

Prognostic potential of CUL3 ligase with differential roles in luminal A and basal type breast cancer tumors

Vasiliki Pantazi, Vanda Miklós, Paul Smith, Orsolya Oláh-Németh, Gabriella Pankotai-Bodó, Divya Teja Dondapati, Ferhan Ayaydin, Vincenzo D’Angiolella, Tibor Pankotai

Sci Rep. 2024; 14: 14912. Published online 2024 Jun 28. doi: 10.1038/s41598-024-65692-z

PMCID:: PMC11213933

Abstract Article PDF–9.8M

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 109210663.

Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex

Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt M Kessler

Life Sci Alliance. 2024 May; 7(5): e202302245. Published online 2024 Mar 7. doi: 10.26508/lsa.202302245

PMCID:: PMC10921066

Abstract Article PDF–3.2M

Select item 108832804.

Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation

Chop Yan Lee, Dalmira Hubrich, Julia K Varga, Christian Schäfer, Mareen Welzel, Eric Schumbera, Milena Djokic, Joelle M Strom, Jonas Schönfeld, Johanna L Geist, Feyza Polat, Toby J Gibson, Claudia Isabelle Keller Valsecchi, Manjeet Kumar, Ora Schueler-Furman, Katja Luck

Mol Syst Biol. 2024 Feb; 20(2): 75–97. Published online 2024 Jan 15. doi: 10.1038/s44320-023-00005-6

PMCID:: PMC10883280

Abstract Article PDF–3.4M

Select item 107002185.

BCLAF1-induced HIF-1α accumulation under normoxia enhances PD-L1 treatment resistances via BCLAF1-CUL3 complex

Bowen Yao, Ye Lu, Yazhao Li, Yixue Bai, Xinyu Wei, Yuanyuan Yang, Demao Yao

Cancer Immunol Immunother. 2023 Dec; 72(12): 4279–4292. Published online 2023 Oct 31. doi: 10.1007/s00262-023-03563-8

PMCID:: PMC10700218

Abstract Article PDF–7.4M

Select item 105646226.

Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly

Roslin J. Adamson, N Connor Payne, Sergio G. Bartual, Ralph Mazitschek, Alex N. Bullock

Free Radic Biol Med. 2023 Aug 1; 204: 215–225. doi: 10.1016/j.freeradbiomed.2023.04.021

PMCID:: PMC10564622

Abstract Article PDF–5.7M

Select item 104139337.

Structure and Function of RhoBTB1 Required for Substrate Specificity and Cullin-3 Ubiquitination

Gaurav Kumar, Shi Fang, Daria Golosova, Ko-Ting Lu, Daniel T Brozoski, Ibrahim Vazirabad, Curt D Sigmund

Function (Oxf) 2023; 4(5): zqad034. Published online 2023 Jul 3. doi: 10.1093/function/zqad034

PMCID:: PMC10413933

Abstract Article PDF–1.4M

Select item 103300588.

Renal effects of Cullin 3 mutations causing Familial Hyperkalemic Hypertension

Ryan J. Cornelius, Yujiro Maeoka, James A. McCormick

Curr Opin Nephrol Hypertens. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Curr Opin Nephrol Hypertens. 2023 Jul 1; 32(4): 335–343. Published online 2023 Apr 12. doi: 10.1097/MNH.0000000000000891

PMCID:: PMC10330058

Abstract Article PDF–902K

Select item 102841179.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 1024019910.

UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis

Lucile Guerber, Aurore Vuidel, Yongrong Liao, Charlotte Kleiss, Erwan Grandgirard, Izabela Sumara, Evanthia Pangou

EMBO Rep. 2023 Jun; 24(6): e56241. Published online 2023 Apr 11. doi: 10.15252/embr.202256241

PMCID:: PMC10240199

Abstract Article PDF–4.9M

Select item 1023742211.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1019062112.

DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1‐Mediated NRF2 Ubiquitination

Xin Wang, Tangjun Zhou, Xiao Yang, Xiankun Cao, Gu Jin, Pu Zhang, Jiadong Guo, Kewei Rong, Baixing Li, Yibin Hu, Kexin Liu, Peixiang Ma, An Qin, Jie Zhao

Adv Sci (Weinh) 2023 May; 10(14): 2204438. Published online 2023 Mar 25. doi: 10.1002/advs.202204438

PMCID:: PMC10190621

Abstract Article PDF–7.3M

Select item 1018949513.

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia

Yu-Han H. Hsu, Greta Pintacuda, Ruize Liu, Eugeniu Nacu, April Kim, Kalliopi Tsafou, Natalie Petrossian, William Crotty, Jung Min Suh, Jackson Riseman, Jacqueline M. Martin, Julia C. Biagini, Daya Mena, Joshua K.T. Ching, Edyta Malolepsza, Taibo Li, Tarjinder Singh, Tian Ge, Shawn B. Egri, Benjamin Tanenbaum, Caroline R. Stanclift, Annie M. Apffel, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Steven A. Carr, Monica Schenone, Jake Jaffe, Nadine Fornelos, Hailiang Huang, Kevin C. Eggan, Kasper Lage

iScience. 2023 May 19; 26(5): 106701. Published online 2023 Apr 18. doi: 10.1016/j.isci.2023.106701

PMCID:: PMC10189495

Abstract Article PDF–5.3M

Select item 1014884714.

Prenatal phthalate exposure and cord blood DNA methylation

Jooah Lee, Jeeyoung Kim, Sabrina Shafi Zinia, Jaehyun Park, Sungho Won, Woo Jin Kim

Sci Rep. 2023; 13: 7046. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33002-8

PMCID:: PMC10148847

Abstract Article PDF–1.1M

Select item 1011960215.

Latent CSN-CRL complexes are crucial for curcumin-induced apoptosis and recruited during adipogenesis to lipid droplets via small GTPase RAB18

Dawadschargal Dubiel, Jing Wang, Roland Hartig, Supattra Chaithongyot, Wolfgang Dubiel, Michael Naumann

iScience. 2023 Apr 21; 26(4): 106468. Published online 2023 Mar 22. doi: 10.1016/j.isci.2023.106468

PMCID:: PMC10119602

Abstract Article PDF–6.6M

Select item 1009264316.

BAG6 supports stress fiber formation by preventing the ubiquitin-mediated degradation of RhoA

Maho Miyauchi, Reina Matsumura, Hiroyuki Kawahara

Mol Biol Cell. 2023 Apr 1; 34(4): ar34. Published online 2023 Mar 17. doi: 10.1091/mbc.E22-08-0355

PMCID:: PMC10092643

Abstract Article PDF–23M

Select item 1003899217.

Calpain activity is negatively regulated by a KCTD7–Cullin-3 complex via non-degradative ubiquitination

Jaiprakash Sharma, Shalaka Mulherkar, Uan-I Chen, Yan Xiong, Lakshya Bajaj, Byoung-Kyu Cho, Young Ah Goo, Hon-Chiu Eastwood Leung, Kimberley F. Tolias, Marco Sardiello

Cell Discov. 2023; 9: 32. Published online 2023 Mar 24. doi: 10.1038/s41421-023-00533-3

PMCID:: PMC10038992

Abstract Article PDF–15M

Select item 1001989218.

BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation

Jingfei Li, Haotian Lin, Tinghui Fan, Linfei Huang, Xinyong Zhang, Yanhong Tai, Yi Fang, Qihong Li, Ruzhou Zhao, Penghao Wang, Li Zhou, Luming Wan, Yuhua Wu, Hui Zhong, Congwen Wei, Xiaopan Yang

Front Cell Infect Microbiol. 2023; 13: 1134511. Published online 2023 Mar 2. doi: 10.3389/fcimb.2023.1134511

PMCID:: PMC10019892

Abstract Article PDF–9.6M

Select item 1001172319.

KLHL12 can form large COPII structures in the absence of CUL3 neddylation

Tamara Moretti, Kyungho Kim, Astha Tuladhar, Jinoh Kim

Mol Biol Cell. 2023 Mar 1; 34(3): br4. Published online 2023 Feb 21. doi: 10.1091/mbc.E22-08-0383

PMCID:: PMC10011723

Abstract Article PDF–1.2M

Select item 995044720.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

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