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Items: 1 to 20 of 76

1.
Dorsal visual stream and LIMK1: hemideletion, haplotype, and enduring effects in children with Williams syndrome
J. Shane Kippenhan, Michael D. Gregory, Tiffany Nash, Philip Kohn, Carolyn B. Mervis, Daniel P. Eisenberg, Madeline H. Garvey, Katherine Roe, Colleen A. Morris, Bhaskar Kolachana, Ariel M. Pani, Leah Sorcher, Karen F. Berman
J Neurodev Disord. 2023; 15: 29. Published online 2023 Aug 26. doi: 10.1186/s11689-023-09493-x
PMCID:
PMC10464045
AbstractArticlePDF–2.5M
2.
The Activation of the LIMK/Cofilin Signaling Pathway via Extracellular Matrix–Integrin Interactions Is Critical for the Generation of Mature and Vascularized Cardiac Organoids
Ji-Min Noh, Seung-Cheol Choi, Myeong-Hwa Song, Kyung Seob Kim, Seongmin Jun, Jae Hyoung Park, Ju Hyeon Kim, Kyoungmi Kim, Tae Hee Ko, Jong-Il Choi, Jeong-An Gim, Jong-Hoon Kim, Yongjun Jang, Yongdoo Park, Ji Eun Na, Im Joo Rhyu, Do-Sun Lim
Cells. 2023 Aug; 12(16): 2029. Published online 2023 Aug 9. doi: 10.3390/cells12162029
PMCID:
PMC10453200
AbstractArticlePDF–6.8M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
5.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
6.
Cleavage and activation of LIM kinase 1 as a novel mechanism for calpain 2-mediated regulation of nuclear dynamics
L. Rodríguez-Fernández, S. Company, R. Zaragozá, J. R. Viña, E. R. García-Trevijano
Sci Rep. 2021; 11: 16339. Published online 2021 Aug 11. doi: 10.1038/s41598-021-95797-8
PMCID:
PMC8358030
AbstractArticlePDF–2.5M
7.
Long non-coding RNA Lnc-408 promotes invasion and metastasis of breast cancer cell by regulating LIMK1
Yina Qiao, Ting Jin, Shengdong Guan, Shaojie Cheng, Siyang Wen, Huan Zeng, Maojia Zhao, Liping Yang, Xueying Wan, Yuxiang Qiu, Qiao Li, Manran Liu, Yixuan Hou
Oncogene. 2021; 40(24): 4198–4213. Published online 2021 Jun 2. doi: 10.1038/s41388-021-01845-y
PMCID:
PMC8211561
AbstractArticlePDF–7.7M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
LIMK1 promotes peritoneal metastasis of gastric cancer and is a therapeutic target
Xi Kang, Weilin Li, Weixin Liu, Han Liang, Jingyu Deng, Chi Chun Wong, Sinan Zhao, Wei Kang, Ka Fai To, Philip Wai Yan Chiu, Guiying Wang, Jun Yu, Enders Kwok Wai Ng
Oncogene. 2021; 40(19): 3422–3433. Published online 2021 Apr 21. doi: 10.1038/s41388-021-01656-1
PMCID:
PMC8116207
AbstractArticlePDF–4.9M
10.
FOXD3-AS1/miR-128-3p/LIMK1 axis regulates cervical cancer progression
Xiufang Yang, Huilan Du, Wenhui Bian, Qingxue Li, Hairu Sun
Oncol Rep. 2021 May; 45(5): 62. Published online 2021 Mar 16. doi: 10.3892/or.2021.8013
PMCID:
PMC8020211
AbstractArticlePDF–2.7M
11.
Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G-actin signaling cascade
Xun Wang, Shuang Zou, Tong Ren, Li-Jun Zhao, Li-Fei Yu, Xiang-Yu Li, Xin Yan, Li-Jun Zhang
Int J Mol Med. 2021 May; 47(5): 68. Published online 2021 Mar 1. doi: 10.3892/ijmm.2021.4901
PMCID:
PMC7952248
AbstractArticlePDF–1.2M
12.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
13.
Effects of PAK4/LIMK1/Cofilin‐1 signaling pathway on proliferation, invasion, and migration of human osteosarcoma cells
Zhi‐Feng Li, Yin‐Di Yao, Yin‐Yin Zhao, Yan Liu, Zhen‐Hua Liu, Pei Hu, Zhuo‐Ran Zhu
J Clin Lab Anal. 2020 Sep; 34(9): e23362. Published online 2020 May 28. doi: 10.1002/jcla.23362
PMCID:
PMC7521293
AbstractArticlePDF–1.2M
14.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
15.
Human Natural Killer Cell Cytoskeletal Dynamics and Cytotoxicity are Regulated by LIM Kinase
Melody G. Duvall, Mary E. Fuhlbrigge, Roisin B. Reilly, Katherine H. Walker, Ayşe Kılıç, Bruce D. Levy
J Immunol. Author manuscript; available in PMC 2021 Aug 1.
Published in final edited form as: J Immunol. 2020 Aug 1; 205(3): 801–810. Published online 2020 Jul 8. doi: 10.4049/jimmunol.2000186
PMCID:
PMC7391245
AbstractArticlePDF–1.8M
16.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
17.
ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly
Rochelle Tixeira, Thanh Kha Phan, Sarah Caruso, Bo Shi, Georgia K. Atkin-Smith, Christina Nedeva, Jenny D. Y. Chow, Hamsa Puthalakath, Mark D. Hulett, Marco J. Herold, Ivan K. H. Poon
Cell Death Differ. 2020 Jan; 27(1): 102–116. Published online 2019 May 1. doi: 10.1038/s41418-019-0342-5
PMCID:
PMC7206021
AbstractArticlePDF–2.9M
18.
Up‐regulation of LIMK1 expression in prostate cancer is correlated with poor pathological features, lymph node metastases and biochemical recurrence
Jin‐Bei Huang, Yu‐Peng Wu, Yun‐Zhi Lin, Hai Cai, Shao‐Hao Chen, Xiong‐Lin Sun, Xiao‐Dong Li, Yong Wei, Qing‐Shui Zheng, Ning Xu, Xue‐Yi Xue
J Cell Mol Med. 2020 Apr; 24(8): 4698–4706. Published online 2020 Mar 13. doi: 10.1111/jcmm.15138
PMCID:
PMC7176864
AbstractArticlePDF–1.2M
19.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
20.
Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion
Joseph Chen, Badriprasad Ananthanarayanan, Kelsey S. Springer, Kayla J. Wolf, Sharon M. Sheyman, Vivien D. Tran, Sanjay Kumar
Cancer Res. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Cancer Res. 2020 Jan 1; 80(1): 69–78. Published online 2019 Oct 22. doi: 10.1158/0008-5472.CAN-19-1237
PMCID:
PMC6942638
AbstractArticlePDF–1.8M

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