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Select item 101772181.

The Role of Eosinophil-Derived Neurotoxin and Vascular Endothelial Growth Factor in the Pathogenesis of Eosinophilic Asthma

Maciej Tota, Julia Łacwik, Julia Laska, Łukasz Sędek, Krzysztof Gomułka

Cells. 2023 May; 12(9): 1326. Published online 2023 May 6. doi: 10.3390/cells12091326

PMCID:: PMC10177218

Abstract Article PDF–1.3M

Select item 101312842.

RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication

Eugenia Z. Ong, Clara W.T. Koh, Danny J.H. Tng, Justin S.G. Ooi, Jia Xin Yee, Valerie S.Y. Chew, Yan Shan Leong, Kurugulasigamoney Gunasegaran, Chin Pin Yeo, Lynette L.E. Oon, Jean X.Y. Sim, Kuan Rong Chan, Jenny G. Low, Eng Eong Ooi

Med. 2023 Jun 9; 4(6): 353–360.e2. Published online 2023 Apr 26. doi: 10.1016/j.medj.2023.04.001

PMCID:: PMC10131284

Abstract Article PDF–3.0M

Select item 100339373.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 88996634.

RNASE2 Mediates Age-Associated B Cell Expansion Through Monocyte Derived IL-10 in Patients With Systemic Lupus Erythematosus

Yantong Zhu, Xiaojun Tang, Yang Xu, Si Wu, Weilin Liu, Linyu Geng, Xiaolei Ma, Betty P. Tsao, Xuebing Feng, Lingyun Sun

Front Immunol. 2022; 13: 752189. Published online 2022 Feb 21. doi: 10.3389/fimmu.2022.752189

PMCID:: PMC8899663

Abstract Article PDF–6.5M

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 64821076.

Integrative approach identifies corticosteroid response variant in diverse populations with asthma

Albert M. Levin, Hongsheng Gui, Natalia Hernandez-Pacheco, Mao Yang, Shujie Xiao, James J. Yang, Samantha Hochstadt, Andrea J. Barczak, Walter L. Eckalbar, Dean Rynkowski, Lesly-Anne Samedy, Pui-Yan Kwok, Maria Pino-Yanes, David J. Erle, David E. Lanfear, Esteban G. Burchard, L. Keoki Williams

J Allergy Clin Immunol. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: J Allergy Clin Immunol. 2019 May; 143(5): 1791–1802. Published online 2018 Oct 24. doi: 10.1016/j.jaci.2018.09.034

PMCID:: PMC6482107

Abstract Article PDF–1.2M

Select item 58410867.

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Samuel A. Hasson, Lesley A. Kane, Koji Yamano, Chiu-Hui Huang, Danielle A. Sliter, Eugen Buehler, Chunxin Wang, Sabrina M. Heman-Ackah, Tara Hessa, Rajarshi Guha, Scott E. Martin, Richard J. Youle

Nature. Author manuscript; available in PMC 2018 Mar 7.

Published in final edited form as: Nature. 2013 Dec 12; 504(7479): 291–295. Published online 2013 Nov 24. doi: 10.1038/nature12748

PMCID:: PMC5841086

Abstract Article PDF–5.3M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 37735059.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 359075610.

Eosinophil-Derived Neurotoxin Is Elevated in Patients with Amyotrophic Lateral Sclerosis

Guan-Ting Liu, Chi-Shin Hwang, Chia-Hung Hsieh, Chih-Hao Lu, Sunny Li-Yun Chang, Jin-Ching Lee, Chien-Fu Huang, Hao-Teng Chang

Mediators Inflamm. 2013; 2013: 421389. Published online 2013 Feb 20. doi: 10.1155/2013/421389

PMCID:: PMC3590756

Abstract Article PDF–674K

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311016512.

Effects of Chronic Ascariasis and Trichuriasis on Cytokine Production and Gene Expression in Human Blood: A Cross-Sectional Study

Miguel Reina Ortiz, Fernanda Schreiber, Susana Benitez, Nely Broncano, Martha E. Chico, Maritza Vaca, Neal Alexander, David J. Lewis, Gordon Dougan, Philip J. Cooper

PLoS Negl Trop Dis. 2011 Jun; 5(6): e1157. Published online 2011 Jun 7. doi: 10.1371/journal.pntd.0001157

PMCID:: PMC3110165

Abstract Article PDF–366K

Select item 291670613.

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

Dermot P.B. McGovern, Michelle R. Jones, Kent D. Taylor, Kristin Marciante, Xiaofei Yan, Marla Dubinsky, Andy Ippoliti, Eric Vasiliauskas, Dror Berel, Carrie Derkowski, Deb Dutridge, International IBD Genetics Consortium, Phil Fleshner, David Q. Shih, Gil Melmed, Emebet Mengesha, Lily King, Sheila Pressman, Talin Haritunians, Xiuqing Guo, Stephan R. Targan, Jerome I. Rotter

Hum Mol Genet. 2010 Sep 1; 19(17): 3468–3476. Published online 2010 Jun 22. doi: 10.1093/hmg/ddq248

PMCID:: PMC2916706

Abstract Article PDF–196K

Select item 285225314.

Eosinophil Ribonucleases and Their Cutaneous Lesion-Forming Activity

Douglas A. Plager, Mark D. P. Davis, Amy G. Andrews, Michael J. Coenen, Terry J. George, Gerald J. Gleich, Kristin M. Leiferman

J Immunol. Author manuscript; available in PMC 2010 Sep 15.

Published in final edited form as: J Immunol. 2009 Sep 15; 183(6): 4013–4020. Published online 2009 Aug 28. doi: 10.4049/jimmunol.0900055

PMCID:: PMC2852253

Abstract Article PDF–2.2M

Select item 284748215.

Human Ribonuclease A Superfamily Members, Eosinophil-Derived Neurotoxin and Pancreatic Ribonuclease, Induce Dendritic Cell Maturation and Activation

De Yang, Qian Chen, Helene F. Rosenberg, Susanna M. Rybak, Dianne L. Newton, Zhao Yuan Wang, Qin Fu, Velizar T. Tchernev, Minjuan Wang, Barry Schweitzer, Stephen F. Kingsmore, Dhavalkumar D. Patel, Joost J. Oppenheim, O. M. Zack Howard

J Immunol. Author manuscript; available in PMC 2010 Mar 30.

Published in final edited form as: J Immunol. 2004 Nov 15; 173(10): 6134–6142. doi: 10.4049/jimmunol.173.10.6134

PMCID:: PMC2847482

Abstract Article PDF–1.5M

Select item 259607916.

Variation in genes encoding eosinophil granule proteins in atopic dermatitis patients from Germany

Qumar Parwez, Susanne Stemmler, Jörg T Epplen, Sabine Hoffjan

J Negat Results Biomed. 2008; 7: 9. Published online 2008 Nov 13. doi: 10.1186/1477-5751-7-9

PMCID:: PMC2596079

Abstract Article PDF–224K

Select item 223435717.

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses

De Yang, Qian Chen, Shao Bo Su, Ping Zhang, Kahori Kurosaka, Rachel R. Caspi, Suzanne M. Michalek, Helene F. Rosenberg, Ning Zhang, Joost J. Oppenheim

J Exp Med. 2008 Jan 21; 205(1): 79–90. doi: 10.1084/jem.20062027

PMCID:: PMC2234357

Abstract Article PDF–2.0M

Select item 217494718.

Transcriptional regulation of human eosinophil RNases by an evolutionary- conserved sequence motif in primate genome

Hsiu-Yu Wang, Hao-Teng Chang, Tun-Wen Pai, Chung-I Wu, Yuan-Hung Lee, Yen-Hsin Chang, Hsiu-Ling Tai, Chuan-Yi Tang, Wei-Yao Chou, Margaret Dah-Tsyr Chang

BMC Mol Biol. 2007; 8: 89. Published online 2007 Oct 11. doi: 10.1186/1471-2199-8-89

PMCID:: PMC2174947

Abstract Article PDF–2.1M

Select item 196836519.

Characterisation of UGP and its relationship with beta-core fragment.

A. Kardana, K. D. Bagshawe, B. Coles, D. Read, M. Taylor

Br J Cancer. 1993 Apr; 67(4): 686–692. doi: 10.1038/bjc.1993.127

PMCID:: PMC1968365

Summary Page Browse PDF–1.1M

Select item 190671020.

Urinary Eosinophil Protein X in Children with Atopic Asthma

M. Nuijsink, W. C. J. Hop, P. J. Sterk, E. J. Duiverman, P. S. Hiemstra, J. C. de Jongste

Mediators Inflamm. 2007; 2007: 49240. Published online 2007 Jun 13. doi: 10.1155/2007/49240

PMCID:: PMC1906710

Abstract Article PDF–517K

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