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Items: 1 to 20 of 50

1.
Multifaceted investigation underlies diverse mechanisms contributing to the downregulation of Hedgehog pathway-associated genes INTU and IFT88 in lung adenocarcinoma and uterine corpus endometrial carcinoma
Ho Yin Edwin Chan, Zhefan Stephen Chen
Aging (Albany NY) 2022 Oct 15; 14(19): 7794–7823. Published online 2022 Sep 7. doi: 10.18632/aging.204262
PMCID:
PMC9596204
AbstractArticlePDF–4.8M
2.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
3.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
4.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
5.
Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening
Antonella Falconieri, Giovanni Minervini, Federica Quaglia, Geppo Sartori, Silvio C. E. Tosatto
Cancers (Basel) 2022 Feb; 14(4): 1009. Published online 2022 Feb 17. doi: 10.3390/cancers14041009
PMCID:
PMC8869832
AbstractArticlePDF–1.1M
6.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
Association of IFT88 gene variants with nonsyndromic cleft lip with or without cleft palate
Amanda Barba, Christian Urbina, Lorena Maili, Brett Chiquet, Susan H. Blanton, Jacqueline T. Hecht, Ariadne Letra
Birth Defects Res. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Birth Defects Res. 2019 Jul 1; 111(11): 659–665. Published online 2019 Apr 5. doi: 10.1002/bdr2.1504
PMCID:
PMC7227388
AbstractArticlePDF–83K
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
IFT88 controls NuMA enrichment at k-fibers minus-ends to facilitate their re-anchoring into mitotic spindles
Nicolas Taulet, Audrey Douanier, Benjamin Vitre, Christelle Anguille, Justine Maurin, Yann Dromard, Virginie Georget, Benedicte Delaval
Sci Rep. 2019; 9: 10311. Published online 2019 Jul 16. doi: 10.1038/s41598-019-46605-x
PMCID:
PMC6635507
AbstractArticlePDF–1.7M
11.
Biallelic Mutations in LRRC56, Encoding a Protein Associated with Intraflagellar Transport, Cause Mucociliary Clearance and Laterality Defects
Serge Bonnefoy, Christopher M. Watson, Kristin D. Kernohan, Moara Lemos, Sebastian Hutchinson, James A. Poulter, Laura A. Crinnion, Ian Berry, Jennifer Simmonds, Pradeep Vasudevan, Chris O’Callaghan, Robert A. Hirst, Andrew Rutman, Lijia Huang, Taila Hartley, David Grynspan, Eduardo Moya, Chunmei Li, Ian M. Carr, David T. Bonthron, Michel Leroux, Care4Rare Canada Consortium, Kym M. Boycott, Philippe Bastin, Eamonn G. Sheridan
Am J Hum Genet. 2018 Nov 1; 103(5): 727–739. Published online 2018 Nov 1. doi: 10.1016/j.ajhg.2018.10.003
PMCID:
PMC6218757
AbstractArticlePDF–2.1M
12.
IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis.
Anil Chekuri, Aditya A. Guru, Pooja Biswas, Kari Branham, Shyamanga Borooah, Angel Soto-Hermida, Michael Hicks, Naheed W. Khan, Hiroko Matsui, Akhila Alapati, Pongali B Raghavendra, Susanne Roosing, Sripriya Srivatsan, Sinnakaruppan Mathavan, Amalio Telenti, John R. Heckenlively, S. Amer Riazuddin, Kelly A. Frazer, Paul A. Sieving, Radha Ayyagari
Hum Genet. Author manuscript; available in PMC 2019 Jul 5.
Published in final edited form as: Hum Genet. 2018 Jul; 137(6-7): 447–458. Published online 2018 Jul 5. doi: 10.1007/s00439-018-1897-9
PMCID:
PMC6150774
AbstractArticlePDF–496K
13.
Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate
Hua Tian, Jifan Feng, Jingyuan Li, Thach-Vu Ho, Yuan Yuan, Yang Liu, Frederick Brindopke, Jane C. Figueiredo, William Magee, III, Pedro A. Sanchez-Lara, Yang Chai
Hum Mol Genet. 2017 Mar 1; 26(5): 860–872. Published online 2017 Jan 9. doi: 10.1093/hmg/ddx002
PMCID:
PMC6075526
AbstractArticlePDF–1.5M
14.
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening
Rueyhung Roc Weng, T. Tony Yang, Chia-En Huang, Chih-Wei Chang, Won-Jing Wang, Jung-Chi Liao
Biophys J. 2018 Jul 17; 115(2): 263–275. Published online 2018 Jun 1. doi: 10.1016/j.bpj.2018.04.051
PMCID:
PMC6050714
AbstractArticlePDF–5.7M
15.
CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement
Tina Beyer, Sylvia Bolz, Katrin Junger, Nicola Horn, Muhammad Moniruzzaman, Yasmin Wissinger, Marius Ueffing, Karsten Boldt
Mol Cell Proteomics. 2018 Jul; 17(7): 1285–1294. Published online 2018 Apr 3. doi: 10.1074/mcp.RA117.000487
PMCID:
PMC6030719
AbstractArticlePDF–2.7M
16.
Basic fibroblast growth factor increases IFT88 expression in chondrocytes
Daolu Zhan, Wei Xiang, Fengjing Guo, Yuanzheng Ma
Mol Med Rep. 2017 Nov; 16(5): 6590–6599. Published online 2017 Sep 8. doi: 10.3892/mmr.2017.7449
PMCID:
PMC5865803
AbstractArticlePDF–2.4M
17.
Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair
Huiming Lu, Raghavendra A. Shamanna, Jessica K. de Freitas, Mustafa Okur, Prabhat Khadka, Tomasz Kulikowicz, Priscella P. Holland, Jane Tian, Deborah L. Croteau, Anthony J. Davis, Vilhelm A. Bohr
Nat Commun. 2017; 8: 2039. Published online 2017 Dec 11. doi: 10.1038/s41467-017-02146-3
PMCID:
PMC5725494
AbstractArticlePDF–4.0M
18.
The CEP19-RABL2 GTPase complex binds IFT-B to initiate intraflagellar transport at the ciliary base
Tomoharu Kanie, Keene Louis Abbott, Nancie Ann Mooney, Edward Douglas Plowey, Janos Demeter, Peter Kent Jackson
Dev Cell. Author manuscript; available in PMC 2018 Jul 10.
Published in final edited form as: Dev Cell. 2017 Jul 10; 42(1): 22–36.e12. Published online 2017 Jun 15. doi: 10.1016/j.devcel.2017.05.016
PMCID:
PMC5556974
AbstractArticlePDF–2.2M
19.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
20.
Transcriptome profiling identifies a recurrent CRYL1-IFT88 chimeric transcript in hepatocellular carcinoma
Yi Huang, Jiaying Zheng, Dunyan Chen, Feng Li, Wenbing Wu, Xiaoli Huang, Yanan Wu, Yangyang Deng, Funan Qiu
Oncotarget. 2017 Jun 20; 8(25): 40693–40704. Published online 2017 Apr 19. doi: 10.18632/oncotarget.17244
PMCID:
PMC5522265
AbstractArticlePDF–2.2M

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