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Select item 104707911.

Association among VKORC1 rs9923231, CYP4F2 rs2108622, GGCX rs11676382 polymorphisms and acute ischemic stroke

Silvina Iluţ, Ştefan Cristian Vesa, Vitalie Văcăraş, Diana Şipoş-Lascu, Cristina Bârsan, Raluca Maria Pop, Sorin Crişan, Antonia Eugenia Macarie, Camelia Alexandra Coadă, Lăcrămioara Perju-Dumbravă, Dafin Fior Muresanu, Anca Dana Buzoianu

Medicine (Baltimore) 2023 Aug 25; 102(34): e34836. Published online 2023 Aug 25. doi: 10.1097/MD.0000000000034836

PMCID:: PMC10470791

Abstract Article PDF–661K

Select item 103789782.

Frequency of polymorphisms in the CYP2C9, VKORC1, and CYP4F2 genes related to the metabolism of Warfarin in healthy donors from Cali, Colombia

Sebastian Giraldo-Ocampo, Lorena Diaz-Ordoñez, Yisther Katherine Silva-Cuero, Juan David Gutierrez-Medina, Estephania Candelo, Javier A. Diaz, Harry Pachajoa

Medicine (Baltimore) 2023 Jul 28; 102(30): e34204. Published online 2023 Jul 28. doi: 10.1097/MD.0000000000034204

PMCID:: PMC10378978

Abstract Article PDF–630K

Select item 103184523.

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels

Julia T. Tanzo, Veronica L. Li, Amanda L. Wiggenhorn, Maria Dolores Moya-Garzon, Wei Wei, Xuchao Lyu, Wentao Dong, Usman A. Tahir, Zsu-Zsu Chen, Daniel E. Cruz, Shuliang Deng, Xu Shi, Shuning Zheng, Yan Guo, Mario Sims, Monther Abu-Remaileh, James G. Wilson, Robert E. Gerszten, Jonathan Z. Long, Mark D. Benson

J Biol Chem. 2023 Jun; 299(6): 104764. Published online 2023 Apr 28. doi: 10.1016/j.jbc.2023.104764

PMCID:: PMC10318452

Abstract Article PDF–2.6M

Select item 101706974.

Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact

Mahvash Farajzadeh-Dehkordi, Ladan Mafakher, Fatemeh Samiee-Rad, Babak Rahmani

BMC Mol Cell Biol. 2023; 24: 17. Published online 2023 May 9. doi: 10.1186/s12860-023-00479-0

PMCID:: PMC10170697

Abstract Article PDF–2.2M

Select item 98362955.

Suggestive evidence of CYP4F2 gene polymorphisms with HAPE susceptibility in the Chinese Han population

Lining Si, Haiyuan Wang, Rong Wang, Lhachen Tsering, Qifu Long, Yahui Jiang, Yun Yi, Yanli Zhao

PLoS One. 2023; 18(1): e0280136. Published online 2023 Jan 12. doi: 10.1371/journal.pone.0280136

PMCID:: PMC9836295

Abstract Article PDF–1.1M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77975497.

Influence of CYP4F2, ApoE, and CYP2A6 gene polymorphisms on the variability of Warfarin dosage requirements and susceptibility to cardiovascular disease in Jordan

Laith N. AL-Eitan, Ayah Y. Almasri, Adan H. Alnaamneh, Hatem A. Aman, Nasr N. Alrabadi, Rame H Khasawneh, Mansour A. Alghamdi

Int J Med Sci. 2021; 18(3): 826–834. Published online 2021 Jan 1. doi: 10.7150/ijms.51546

PMCID:: PMC7797549

Abstract Article PDF–408K

Select item 76750008.

A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos

Elena V. Feofanova, Han Chen, Yulin Dai, Peilin Jia, Megan L. Grove, Alanna C. Morrison, Qibin Qi, Martha Daviglus, Jianwen Cai, Kari E. North, Cathy C. Laurie, Robert C. Kaplan, Eric Boerwinkle, Bing Yu

Am J Hum Genet. 2020 Nov 5; 107(5): 849–863. Published online 2020 Oct 7. doi: 10.1016/j.ajhg.2020.09.003

PMCID:: PMC7675000

Abstract Article PDF–1.8M

Select item 75073649.

Association of genetic variants at CETP, AGER, and CYP4F2 locus with the risk of atrophic age‐related macular degeneration

Rasa Liutkeviciene, Alvita Vilkeviciute, Loresa Kriauciuniene, Mantas Banevicius, Brigita Budiene, Daiva Stanislovaitiene, Reda Zemaitiene, Vytenis P. Deltuva

Mol Genet Genomic Med. 2020 Sep; 8(9): e1357. Published online 2020 Jul 14. doi: 10.1002/mgg3.1357

PMCID:: PMC7507364

Abstract Article PDF–607K

Select item 739697710.

CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation

Stefan Cristian Vesa, Sonia Irina Vlaicu, Vitalie Vacaras, Sorin Crisan, Octavia Sabin, Sergiu Pasca, Adrian Pavel Trifa, Tamas Rusz-Fogarasi, Madalina Sava, Anca Dana Buzoianu

Genes (Basel) 2020 Jul; 11(7): 822. Published online 2020 Jul 20. doi: 10.3390/genes11070822

PMCID:: PMC7396977

Abstract Article PDF–671K

Select item 736661011.

CYP4F2 and CYP3A5 gene polymorphisms and lung cancer in Chinese Han population

Ruiqing He, Meng Li, Anqi Li, Wenhui Dang, Tian Yang, Jing Li, Ning Zhang, Tianbo Jin, Mingwei Chen

Clin Exp Med. 2020; 20(3): 461–468. Published online 2020 Apr 30. doi: 10.1007/s10238-020-00631-6

PMCID:: PMC7366610

Abstract Article PDF–697K

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 716125413.

The correlation between CYP4F2 variants and chronic obstructive pulmonary disease risk in Hainan Han population

Yipeng Ding, Yixiu Yang, Quanni Li, Qiong Feng, Dongchuan Xu, Cibing Wu, Jie Zhao, Xiaoli Zhou, Huan Niu, Ping He, Jianfang Liu, Hongxia Yao

Respir Res. 2020; 21: 86. Published online 2020 Apr 15. doi: 10.1186/s12931-020-01348-6

PMCID:: PMC7161254

Abstract Article PDF–641K

Select item 679711614.

Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation

Sonia Mota-Zamorano, Luz M. González, Enrique Luna, José J. Fernández, Áurea Gómez, Alberto Nieto-Fernández, Nicolás R. Robles, Guillermo Gervasini

PLoS One. 2019; 14(10): e0224129. Published online 2019 Oct 17. doi: 10.1371/journal.pone.0224129

PMCID:: PMC6797116

Abstract Article PDF–773K

Select item 673758915.

Genetic variants in CYP4F2 were significantly correlated with susceptibility to ischemic stroke

Yuan Wu, Junjie Zhao, Yonglin Zhao, Tingqin Huang, Xudong Ma, Honggang Pang, Ming Zhang

BMC Med Genet. 2019; 20: 155. Published online 2019 Sep 11. doi: 10.1186/s12881-019-0888-6

PMCID:: PMC6737589

Abstract Article PDF–710K

Select item 654246116.

Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals

Elisa Danese, Sara Raimondi, Martina Montagnana, Angela Tagetti, Taimour Langaee, Paola Borgiani, Cinzia Ciccacci, Antonio J. Carcas, Alberto M. Borobia, Hoi Y. Tong, Cristina Dávila-Fajardo, Mariana Rodrigues Botton, Stephane Bourgeois, Panos Deloukas, Michael D. Caldwell, Jim K. Burmester, Richard L. Berg, Larisa H. Cavallari, Katarzyna Drozda, Min Huang, Li-Zi Zhao, Han-Jing Cen, Rocio Gonzalez-Conejero, Vanessa Roldan, Yusuke Nakamura, Taisei Mushiroda, Inna Y. Gong, Richard B. Kim, Keita Hirai, Kunihiko Itoh, Carlos Isaza, Leonardo Beltrán, Enrique Jiménez-Varo, Marisa Cañadas-Garre, Alice Giontella, Marianne K. Kringen, Kari Bente Foss Haug, Hye Sun Gwak, Kyung Eun Lee, Pietro Minuz, Ming Ta Michael Lee, Steven A. Lubitz, Stuart Scott, Cristina Mazzaccara, Lucia Sacchetti, Ece Genç, Mahmut Özer, Anil Pathare, Rajagopal Krishnamoorthy, Andras Paldi, Virginie Siguret, Marie-Anne Loriot, Vijay Kumar Kutala, Guilherme Suarez-Kurtz, Jamila Perini, Josh C. Denny, Andrea H. Ramirez, Balraj Mittal, Saurabh Singh Rathore, Hersh Sagreiya, Russ Altman, Mohamed Hossam A. Shahin, Sherief I. Khalifa, Nita A. Limdi, Charles Rivers, Aditi Shendre, Chrisly Dillon, Ivet M. Suriapranata, Hong-Hao Zhou, Sheng-Lan Tan, Vacis Tatarunas, Vaiva Lesauskaite, Yumao Zhang, Anke H. Maitland-van der Zee, Talitha I. Verhoef, Anthonius de Boer, Monica Taljaard, Carlo Federico Zambon, Vittorio Pengo, Jieying Eunice Zhang, Munir Pirmohamed, Julie A. Johnson, Cristiano Fava

Clin Pharmacol Ther. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Clin Pharmacol Ther. 2019 Jun; 105(6): 1477–1491. Published online 2019 Feb 17. doi: 10.1002/cpt.1323

Correction in:: Clin Pharmacol Ther. 2024 Jul 22

PMCID:: PMC6542461

Abstract Article PDF–613K

Select item 596018717.

Impact of VKORC1, CYP4F2 and NQO1 gene variants on warfarin dose requirement in Han Chinese patients with catheter ablation for atrial fibrillation

Jiao Li, Wenlong Yang, Zhonghui Xie, Kun Yu, Yuhua Chen, Kaijun Cui

BMC Cardiovasc Disord. 2018; 18: 96. Published online 2018 May 18. doi: 10.1186/s12872-018-0837-x

PMCID:: PMC5960187

Abstract Article PDF–700K

Select item 581686118.

A Novel Polymorphism in the Promoter of the CYP4A11 Gene Is Associated with Susceptibility to Coronary Artery Disease

Svetlana Sirotina, Irina Ponomarenko, Alexander Kharchenko, Marina Bykanova, Anna Bocharova, Kseniya Vagaytseva, Vadim Stepanov, Mikhail Churnosov, Maria Solodilova, Alexey Polonikov

Dis Markers. 2018; 2018: 5812802. Published online 2018 Feb 1. doi: 10.1155/2018/5812802

PMCID:: PMC5816861

Abstract Article PDF–879K

Select item 580775519.

Cytochrome P450 family 4 subfamily F member 2 (CYP4F2) rs1558139, rs2108622 polymorphisms and susceptibility to several cardiovascular and cerebrovascular diseases

Tao Zhang, Kuiying Yu, Xuhua Li

BMC Cardiovasc Disord. 2018; 18: 29. Published online 2018 Feb 9. doi: 10.1186/s12872-018-0763-y

PMCID:: PMC5807755

Abstract Article PDF–1.0M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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