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Select item 111601631.

Up‐regulation of DNA‐dependent protein kinase correlates with radiation resistance in oral squamous cell carcinoma

Satoru Shintani, Mariko Mihara, Chunnan Li, Yuuji Nakahara, Satoshi Hino, Koh‐ichi Nakashiro, Hiroyuki Hamakawa

Cancer Sci. 2003 Oct; 94(10): 894–900. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01372.x

PMCID:: PMC11160163

Abstract Article PDF–1.8M

Select item 111099642.

DNA-PKcs suppresses illegitimate chromosome rearrangements

Jinglong Wang, Cheyenne A Sadeghi, Richard L Frock

Nucleic Acids Res. 2024 May 22; 52(9): 5048–5066. Published online 2024 Feb 27. doi: 10.1093/nar/gkae140

PMCID:: PMC11109964

Abstract Article PDF–2.9M

Select item 111053863.

IGFBP-3 interacts with NONO and SFPQ in PARP-dependent DNA damage repair in triple-negative breast cancer

Hasanthi C. de Silva, Mike Z. Lin, Leo Phillips, Janet L. Martin, Robert C. Baxter

Cell Mol Life Sci. 2019 May; 76(10): 2015–2030. Published online 2019 Feb 6. doi: 10.1007/s00018-019-03033-4

PMCID:: PMC11105386

Abstract Article PDF–7.3M

Select item 110844404.

PRKDC-Mediated NHEJ May Play a Crucial Role in Aneuploidy of Chromosome 8-Driven Progression of Ovarian Cancer

Wenqing Luan, Hongyan Cheng, Haoling Xie, Huiping Liu, Yicheng Wang, Shang Wang, Xue Ye, Honglan Zhu, Fuchou Tang, Yi Li, Xiaohong Chang

Int J Mol Sci. 2024 May; 25(9): 4825. Published online 2024 Apr 28. doi: 10.3390/ijms25094825

PMCID:: PMC11084440

Abstract Article PDF–12M

Select item 110770715.

DNA-PK controls Apollo’s access to leading-end telomeres

Ceylan Sonmez, Beatrice Toia, Patrik Eickhoff, Andreea Medeea Matei, Michael El Beyrouthy, Björn Wallner, Max E Douglas, Titia de Lange, Francisca Lottersberger

Nucleic Acids Res. 2024 May 8; 52(8): 4313–4327. Published online 2024 Feb 26. doi: 10.1093/nar/gkae105

PMCID:: PMC11077071

Abstract Article PDF–2.6M

Select item 109193296.

DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis

Zhengping Shao, Ryan A. Flynn, Jennifer L. Crowe, Yimeng Zhu, Jialiang Liang, Wenxia Jiang, Fardin Aryan, Patrick Aoude, Carolyn R. Bertozzi, Verna M. Estes, Brian J. Lee, Govind Bhagat, Shan Zha, Eliezer Calo

Nature. Author manuscript; available in PMC 2024 Mar 7.

Published in final edited form as: Nature. 2020 Mar; 579(7798): 291–296. Published online 2020 Feb 26. doi: 10.1038/s41586-020-2041-2

PMCID:: PMC10919329

Abstract Article PDF–5.4M

Select item 105274937.

Chemical inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4⁺ helper and CD8⁺ effector T cells

Ana C Azevedo-Pouly, Lauren E Appell, Lyle Burdine, Lora J Rogers, Lauren C Morehead, Daniel Fil, Melanie Barker, Randall R Rainwater, Zachary J Waldrip, Brian Koss, Marie Schluterman Burdine

Immunol Cell Biol. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Immunol Cell Biol. 2023 Aug; 101(7): 663–671. Published online 2023 May 6. doi: 10.1111/imcb.12651

PMCID:: PMC10527493

Abstract Article PDF–1006K

Select item 104984368.

FAP is critical for ovarian cancer cell survival by sustaining NF-κB activation through recruitment of PRKDC in lipid rafts

Bin Li, Zuo Ding, Ozlem Calbay, Yue Li, Tao Li, Lingtao Jin, Shuang Huang

Cancer Gene Ther. Author manuscript; available in PMC 2023 Sep 13.

Published in final edited form as: Cancer Gene Ther. 2023 Apr; 30(4): 608–621. Published online 2022 Dec 9. doi: 10.1038/s41417-022-00575-x

PMCID:: PMC10498436

Abstract Article PDF–3.1M

Select item 104805359.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1023742210.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1018370211.

Up‐regulation of PRKDC was associated with poor renal dysfunction after renal transplantation: A multi‐centre analysis

Zhijun Cao, Hao Jiang, Chunchun Zhao, Huifeng Zhou, Zheng Ma, Chen Xu, Jianglei Zhang, Minjun Jiang, Zhenfan Wang

J Cell Mol Med. 2023 May; 27(10): 1362–1372. Published online 2023 Apr 1. doi: 10.1111/jcmm.17737

PMCID:: PMC10183702

Abstract Article PDF–4.0M

Select item 1016456412.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 1015161513.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1014884314.

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun

Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y

PMCID:: PMC10148843

Abstract Article PDF–11M

Select item 1013893115.

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage

Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter

Int J Mol Sci. 2023 Apr; 24(8): 7041. Published online 2023 Apr 11. doi: 10.3390/ijms24087041

PMCID:: PMC10138931

Abstract Article PDF–4.0M

Select item 1006833416.

DNA damage repair kinase DNA‐PK and cGAS synergize to induce cancer‐related inflammation in glioblastoma

Clara Taffoni, Johanna Marines, Hanane Chamma, Soumyabrata Guha, Mathilde Saccas, Amel Bouzid, Ana‐Luiza Chaves Valadao, Clément Maghe, Jane Jardine, Mi Kyung Park, Katarzyna Polak, Mara De Martino, Claire Vanpouille‐Box, Maguy Del Rio, Celine Gongora, Julie Gavard, Nicolas Bidère, Min Sup Song, Donovan Pineau, Jean‐Philippe Hugnot, Karima Kissa, Laura Fontenille, Fabien P Blanchet, Isabelle K Vila, Nadine Laguette

EMBO J. 2023 Apr; 42(7): e111961. Published online 2022 Dec 27. doi: 10.15252/embj.2022111961

PMCID:: PMC10068334

Abstract Article PDF–4.7M

Select item 1003750917.

Topoisomerase I Inhibition Radiosensitizing Hepatocellular Carcinoma by RNF144A-mediated DNA-PKcs Ubiquitination and Natural Killer Cell Cytotoxicity

Chiao-Ling Tsai, Po-Sheng Yang, Feng-Ming Hsu, Ann-Lii Cheng, Wan-Ni Yu, Jason Chia-Hsien Cheng

J Clin Transl Hepatol. 2023 Jun 28; 11(3): 614–625. Published online 2023 Jan 4. doi: 10.14218/JCTH.2022.00271

PMCID:: PMC10037509

Abstract Article PDF–10M

Select item 1001537918.

DNA‐PKcs and ATM modulate mitochondrial ADP‐ATP exchange as an oxidative stress checkpoint mechanism

Wei‐Min Chen, Jui‐Chung Chiang, Zengfu Shang, Guillermo Palchik, Ciara Newman, Yuanyuan Zhang, Anthony J Davis, Hsinyu Lee, Benjamin PC Chen

EMBO J. 2023 Mar; 42(6): e112094. Published online 2023 Feb 2. doi: 10.15252/embj.2022112094

PMCID:: PMC10015379

Abstract Article PDF–3.3M

Select item 998681719.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762