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Select item 108350481.

Computational inference of eIF4F complex function and structure in human cancers

Su Wu, Gerhard Wagner

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2313589121. Published online 2024 Jan 24. doi: 10.1073/pnas.2313589121

PMCID:: PMC10835048

Abstract Article PDF–7.7M

Select item 106415242.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 104846823.

Paralogous translation factors target distinct mRNAs to differentially regulate tolerance to oxidative stress in yeast

Joanne Cunningham, Aristeidis P Sfakianos, Paraskevi Kritsiligkou, Christopher J Kershaw, Alan J Whitmarsh, Simon J Hubbard, Mark P Ashe, Chris M Grant

Nucleic Acids Res. 2023 Sep 8; 51(16): 8820–8835. Published online 2023 Jul 14. doi: 10.1093/nar/gkad568

PMCID:: PMC10484682

Abstract Article PDF–1.8M

Select item 102841174.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101586246.

The RNA‐binding protein Snd1/Tudor‐SN regulates hypoxia‐responsive gene expression

Juha Saarikettu, Saara Lehmusvaara, Marko Pesu, Ilkka Junttila, Juha Partanen, Petra Sipilä, Matti Poutanen, Jie Yang, Teemu Haikarainen, Olli Silvennoinen

FASEB Bioadv. 2023 May; 5(5): 183–198. Published online 2023 Feb 21. doi: 10.1096/fba.2022-00115

PMCID:: PMC10158624

Abstract Article PDF–7.2M

Select item 101516157.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 101488438.

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun

Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y

PMCID:: PMC10148843

Abstract Article PDF–11M

Select item 101106809.

Prognostic and functional roles of EIF4G1 in lung squamous cell carcinoma

Baoxin Bai, Lin Dong, Minghao Feng, Zhiwen Zhang, Ying Lu, Zengguang Xu, Yali Liu

Hum Cell. 2023; 36(3): 1099–1107. Published online 2023 Mar 10. doi: 10.1007/s13577-023-00884-9

PMCID:: PMC10110680

Abstract Article PDF–9.3M

Select item 1007290610.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 1006093911.

SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions

Nadejda Korneeva, Md Imtiaz Khalil, Ishita Ghosh, Ruping Fan, Thomas Arnold, Arrigo De Benedetti

Virol J. 2023; 20: 55. Published online 2023 Mar 30. doi: 10.1186/s12985-023-02021-2

PMCID:: PMC10060939

Abstract Article PDF–2.7M

Select item 995044712.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 977601113.

EIF4G1 Is a Potential Prognostic Biomarker of Breast Cancer

Kun Li, Guangqing Tan, Xin Zhang, Weiyu Lu, Jingyi Ren, Yuewen Si, Enoch Appiah Adu-Gyamfi, Fangfang Li, Yingxiong Wang, Biao Xie, Meijiao Wang

Biomolecules. 2022 Dec; 12(12): 1756. Published online 2022 Nov 26. doi: 10.3390/biom12121756

PMCID:: PMC9776011

Abstract Article PDF–3.2M

Select item 977255814.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 976969815.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 970808616.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 962912117.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 956995518.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 953348619.

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop

Yongzhen Mo, Yumin Wang, Yian Wang, Xiangying Deng, Qijia Yan, Chunmei Fan, Shuai Zhang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Qianjin Liao, Can Guo, Yong Li, Guiyuan Li, Zhaoyang Zeng, Weihong Jiang, Wei Xiong, Bo Xiang

Mol Cancer. 2022; 21: 192. Published online 2022 Oct 5. doi: 10.1186/s12943-022-01659-w